Lotrix 5% Lotion 60 ml

Lotrix 5% Lotion 60 ml is prescribed for treatment of scabies (a condition in which tiny mites invades the skin and causes irritation.

Lotrix 5% Lotion 60 ml contains Permethrin as an active ingredient.

Apply Lotrix 5% Lotion 60 ml from head to soles of feet immediately after it is prescribed then wash it off after 8-14hrs by taking a bath or as directed by your doctor.

Avoid getting medication into eyes, nose, mouth or vagina. Rinse your eyes with plenty of water in case of an accident.

Categories: ,

Lotion – Tube








Permethrin 5 %


GSK Consumer Healthcare

Prescription Required


How to use, Side effects, Uses, Formula & Composition


Lotrix 5% Lotion 60 ml belongs to the class of drugs known as insecticides (scabicides and pediculicides).  Lotrix 5% Lotion 60 ml is particularly used to treat infestations due to lice (insects) and mites (Arachnida) on the skin and scalp. Also, the drug is prescribed commonly as the first line of action when “Scabies” is suspected. It is safe for use in children (2 years and above) and adults alike, regarding its use in elderly patients (> 65 years), doctors’ advice must strictly be followed. 

Lotrix 5% Lotion 60 ml is a synthetic pyrethroid acting as a pesticide against a number of pests like lice, ticks, fleas and etc. It has proven to be toxic to the nervous system of lice and also potentially causes respiratory failure in mites by delaying depolarization mechanism and blockage of transmission of nerve impulses.

Lotrix 5% Lotion 60 ml is available in form of cream and lotion meant for external use only. Cream /Lotion is gently massaged over the affected area as directed by your doctor, usually, as a one-time application once or at times twice about a week apart. It may be combined with other medications as well. Common side effects of Lotrix 5% Lotion 60 ml include skin rash, itching, and skin dryness. 


Lotrix 5% Lotion 60 ml is prescribed to children (2 years and above ) and adults for the management of the following conditions:

  • Scabies (caused by Sarcoptes scabiei or itch mite)
  • Lice infestation (caused by ectoparasite- Pediculus humanus capitis)

How does Lotrix 5% Lotion 60 ml work

Lotrix 5% Lotion 60 ml works by acting on the cell membranes of these pests by deranging the positively charged sodium ions influx and subsequent depolarization of the cells. This disturbed polarization cycle leads to its neurotoxic effects in lice and respiratory collapse in mites, thereby killing the pests. 

How to use Lotrix 5% Lotion 60 ml

Lotrix 5% Lotion 60 ml is available in form of cream and lotions meant for external use only to be applied topically with clean hands after washing the area properly and drying afterward. Lotrix 5% Lotion 60 ml is safe for use in adults and children above 2 years of age. Elderly patients can also be treated with Lotrix 5% Lotion 60 ml after the doctor’s advice, due to potential side effects.

Available Potency and forms of Lotrix 5% Lotion 60 ml 
  • Cream – 5% ( 30 g) 
  • Lotion – 5%  (60 ml, 120 ml)


  • Lotrix 5% Lotion 60 ml is used externally only, start with shaking the bottle thoroughly. The lotion is applied to the scalp for lice infestation and itching associated with scabies.
  •  In order to use Lotrix 5% Lotion 60 ml wash your hair and scalp with or without shampoo (it is noteworthy,  use of conditioner must be avoided). Dry your hair with a towel (do not blow-dry).
  •  Start applying Lotrix 5% Lotion 60 ml to your head and hair while protecting your eyes and face. Make sure to cover all of your scalp, hair from the front hairline to the nape of your neck and from behind ears.
  •  Lotrix 5% Lotion 60 ml is left on your head for about 10 minutes, you may cover your head with a shower cap to protect yourself from medication. 
  • Rinse off your scalp and hair with warm water, ensuring no medication remains.
  • Pat dry your hair with a towel, a lice comb with very fine teeth must be used to remove any remaining louse or eggs in the hair. 
  • One application is usually sufficient, but Lotrix 5% Lotion 60 ml can be reapplied after 1 week if any lice remain. 


  • Lotrix 5% Lotion 60 ml is applied on the skin from head to toes in case of scabies. Wash and gently pat dry your skin afterward.
  •  One tube of Lotrix 5% Lotion 60 ml is sufficient for one-time application on the entire body. Start by gently massaging the cream from the head (including the temples, forehead, behind the ears, and neck) to feet including soles.
  • Careful attention must be given to the area between the fingers, and under nails, flexor surfaces (elbows, knees), any kind of skin fold for example under the breasts, waistline, etc.
  • Wash your hands after application, an additional amount can be reapplied if Lotrix 5% Lotion 60 ml gets wiped off from any part.
  •  Lotrix 5% Lotion 60 ml must stay on your body for a minimum of 8-14 hours. Make sure to shower after the prescribed time and change into clean clothes.
  • Previous clothing, bedding, toilet seats, and any personal use items must be washed with warm water and disinfected 
  • Scabies is a contagious condition and can affect people living in close proximity, avoiding close contact, and sharing personal items with people can stop the spread.
  • A one-time application of Lotrix 5% Lotion 60 ml yields efficient results, in case of persistent symptoms medication can be reapplied as described above after 1 week.
Adult Dose

30 grams (1 tube) of 5% cream– Sufficient to cover the entire body

Maximum Safe Dose (One application) – 60 grams of 5% cream

Pediatric Dose

2-4 years – ¼  tube of 30 grams of 5% cream

4-12 years – ½ tube of 30 grams of 5% cream

Elderly Dose

The doctor’s advice is mandatory while treating elderly patients to avoid any harmful effects. Usually,

30 grams of 5% cream (1 tube) or less – Sufficient to cover affected parts

Pregnancy use and lactation

Lotrix 5% Lotion 60 ml is FDA pregnancy risk category B (in animal trials no side effects were evident but, it may also be harmful to the human fetus- lack of clinical data available), therefore if you are pregnant, or are planning to start a family, please consult your doctor. Also, short-term topical use of Lotrix 5% Lotion 60 ml is not known to show any harmful effects. However, please make sure to consult your doctor first before using it. 


Please inform your doctor if you have a history of any before using Lotrix 5% Lotion 60 ml:

  • Allergic reaction to Lotrix 5% Lotion 60 ml 
  • Bronchospasm
  • Infants under 2 years of age

Precautions‌ ‌

Please‌ ‌tell‌ ‌your‌ ‌doctor‌ ‌about‌ ‌any‌ ‌of‌ ‌the‌ ‌following‌ ‌conditions‌ before starting or during the treatment with ‌Lotrix 5% Lotion 60 ml:‌ 

  • If there is a history of allergy to medicines
  • Lotrix 5% Lotion 60 ml may initially cause itching, redness or dryness of skin which can exacerbate pre-existing itching which is temporary
  • Lotrix 5% Lotion 60 ml must no applied over any open wound, mucus membranes, or cuts on the skin
  • Avoid getting Lotrix 5% Lotion 60 ml in your eyes or ingesting it. Thoroughly wash your hands after applying the product
  • Over the counter use of Lotrix 5% Lotion 60 ml in case of lice infestation other than scalp for example in eyelashes, pubic hair is not advised without consulting a doctor first
  • Lotrix 5% Lotion 60 ml contain permethrin which is an insecticide, it may cause asthma attack/ bronchospasm in susceptible individuals
  • In pregnant and lactating women, precaution is advised. Consult your doctor regarding its safety first

Interaction with other medications

Certain medications could interact with Lotrix 5% Lotion 60 ml and may increase or decrease its absorption, in which case, your doctor might alter the treatment. There are no known serious interactions documented in the data, however, it is always best to provide a complete list of drugs you are currently taking to your doctor to avoid any side effects

Adverse effects

Like most medicines, Lotrix 5% Lotion 60 ml has some side effects which include:

Common Side effects:

  • Itching
  • Redness
  • Dryness of skin 
  • Tingling sensation at the site of application 

Rare side effects:

  • Anaphylactic reaction
  • Headache 
  • Dizziness 
  • Irritation in eyes 
  • Abdominal pain
  • nausea/ vomiting 
  • Temporary exacerbation of scabies associated pruritis
  • Difficulty in breathing/ bronchospasm 


  • Allergic Reactions – Allergic reactions to the drug may be mild to severe or potentially could be life-threatening. If allergy is suspected immediately take anti-allergy (anti-histamine) medicine which will stop the mild reaction. If a serious allergic reaction is suspected rush to the nearby hospital and avoid Lotrix 5% Lotion 60 ml and drugs with similar compounds in the future.
  • Headaches- In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
  • Feeling or being sick (nausea or vomiting) or diarrhea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. 
  • Feeling dizzy (lightheaded) or weak –If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
  • Dryness- apply a moisturizer to the skin and wait for 10-15 minutes after which apply Lotrix 5% Lotion 60 ml onto the skin. This will prevent skin from getting dry and flaky.


# 1. HOW TO STORE Lotrix 5% Lotion 60 ml?

Lotrix 5% Lotion 60 ml is to be kept away from the reach of children, in a cool dry place above 25°C,  away from direct sunlight and humidity as that tends to change the chemical nature of certain drugs.

# 2. WHAT IF I USE TOO MUCH OF Lotrix 5% Lotion 60 ml?

In case of too much usage or accidental ingestion, kindly contact your doctor or nearby hospital right away. The amount of medication that can result in severe side effects varies from person to person. Toxicity results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

# 3. HOW IS Lotrix 5% Lotion 60 ml SUPPOSED TO BE TAKEN?

Lotrix 5% Lotion 60 ml  is available in cream and lotion forms to be applied topically.

# 4. WILL Lotrix 5% Lotion 60 ml AFFECT MY SEXUAL ACTIVITY?

Lotrix 5% Lotion 60 ml is prescribed to treat scabies mostly which is contagious. Sexual/physical contact should be avoided. However, the drug does not cause a decrease in libido.

# 5. CAN I TAKE Lotrix 5% Lotion 60 ml DURING MY PREGNANCY?

No, Lotrix 5% Lotion 60 ml should only be used after the doctor’s advice. Topical form may be taken if advised by the doctor for brief periods if absolutely necessary. Consult your doctor regarding the safety of Lotrix 5% Lotion 60 ml first

#6. WILL Lotrix 5% Lotion 60 ml AFFECT MY FERTILITY??

No, there isn’t sufficient evidence to suggest that patients experience a decrease in fertility.


Yes, painkillers are safe to be ingested along with Lotrix 5% Lotion 60 ml 


No, in general Lotrix 5% Lotion 60 ml does not cause dizziness but may occur as a rare side effect. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during the course of your treatment, as it may worsen the dizziness.


It may be used as a single application or multiple (two or three times) at weekly intervals depending on your condition and response under the doctor’s supervision.

# 10 . IS Lotrix 5% Lotion 60 ml SAFE TO GIVE TO ELDERLY PATIENTS?

Lotrix 5% Lotion 60 ml may cause side effects in older people extreme caution is advised when treating elderly patients


No, in general Lotrix 5% Lotion 60 ml does not cause dizziness but may occur as a rare side effect. If this happens, avoid driving till it subsides