Tromit 30mg/ml Injection 1 ml

Categories: ,
Type

Injection

Feature

30mg/1ml

Unit

amp

Formula

Ketorolac Tromethamine

Composition

Ketorolac Tromethamine 30 mg / 1 ml

Brand

Standpharm Pakistan Pvt Ltd

Prescription Required

Yes

How to use, Side effects, Uses, Formula & Composition

About

Tromit 30mg/ml Injection 1 ml belongs to a class of drugs called NSAIDs, more commonly known as analgesics. Tromit 30mg/ml Injection 1 ml is used to manage moderate to severe pain or pain associated with chronic conditions or after a surgical procedure. Tromit 30mg/ml Injection 1 ml is used for short-term management of pain with therapy not exceeding 5 days. Tromit 30mg/ml Injection 1 ml is chemically composed of Ketorolac Tromethamine. 

Tromit 30mg/ml Injection 1 ml works by decreasing the chemical mediators involved in inflammation. Ketorolac, contained in the  Tromit 30mg/ml Injection 1 ml exerts its anti-inflammatory, antipyretic, and analgesic effect by blocking Cyclooxygenase (COX) enzyme involved in inflammatory pathways. 

Tromit 30mg/ml Injection 1 ml is prescribed for a short-term period only, usually not more than 5 days. Given via an Intravenous or intramuscular injection by a health care provider, the dosage must not exceed more than recommended. Tromit 30mg/ml Injection 1 ml can be safely given to adolescents and adults above 17 years of age. The most common side effects of this medication are nausea, vomiting, headache, bloating, heartburn, etc.

Indications

Tromit 30mg/ml Injection 1 ml is prescribed to adults 17 years and above and it is used for the management of pain:

  • Moderate to severe acute pain
  • Post-surgical pain management 
  • Pain associated with chronic conditions

How does Tromit 30mg/ml Injection 1 ml work?

Tromit 30mg/ml Injection 1 ml works by decreasing the chemical mediators involved in inflammation. Ketorolac, contained in the  Tromit 30mg/ml Injection 1 ml exerts its anti-inflammatory, antipyretic, and analgesic effect by nonselective inhibition of the Cyclooxygenase (COX) enzyme involved in inflammatory pathways. 

How to use Tromit 30mg/ml Injection 1 ml?

Tromit 30mg/ml Injection 1 ml is available in form of an injection which can be safely administered both Intravenous and intramuscular by a healthcare professional usually at 6-8 hourly intervals. Dosage recommendations by the doctor must be strictly followed to avoid taking excess. Tromit 30mg/ml Injection 1 ml is only prescribed for short-term relief of pain which should be stopped after 5 days or less. Your doctor may transition you to an oral tablet form for further pain relief. 

Dosage

Adult Dose

Single-dose

Tromit 30mg/ml Injection 1 ml may be administered as an IV or IM injection as a one-time injection of 30 mg/ml.

Divided doses

Alternatively, Tromit 30mg/ml Injection 1 ml may be administered as an IV or IM injection in divided doses every 6-8 hours depending on the pain

Acute moderate to severe pain

  • 30 mg/ml every,  6 hours (IV) OR, 
  • 30 mg/ml every,  6 hours (IM)

Maximum daily safe dose: 120 mg/day

Pediatric Dose

Tromit 30mg/ml Injection 1 ml is not safe to use in children or adolescents below 17 years of age

Elderly dose 

Tromit 30mg/ml Injection 1 ml must be used with caution in patients aged 60 and above. Dose adjustment may be required in case of impaired renal or liver function. Your physician will set the dose most appropriate for your health status. 

Single Dose

Elderly patients should start with a single dose of 15 mg/ml (Intravenous)

Or single-dose- 30 mg/ml (Intramuscular)

Divided doses every 6 hours 

 Intravenous Injection: 15 mg/ml – 6 hourly

Intramuscular Injection: 15 mg/ml – 6 hourly

Maximum Safe dose: 60 mg/day

Pregnancy use and lactation

Tromit 30mg/ml Injection 1 ml is FDA pregnancy risk category C (may be harmful to the fetus causing anomalies), therefore if you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor. Also Tromit 30mg/ml Injection 1 ml is secreted into human milk, if you are breastfeeding Tromit 30mg/ml Injection 1 ml is not recommended, please consult your doctor before taking it.

Contraindications

Please inform your doctor if you have a history of any before using Tromit 30mg/ml Injection 1 ml:

  • Allergic reaction to Tromit 30mg/ml Injection 1 ml or other NSAIDs
  • Peptic/gastric ulcer
  • History of gastric bleeding or perforation
  • history of recent head injury or brain hemorrhage
  • Pregnancy 
  • Renal failure 
  • Pre-surgical administration (may increase risk of bleeding)
  • Children under 17 years of age

Precautions‌

Please‌ ‌tell‌ ‌your‌ ‌doctor‌ ‌about‌ ‌any‌ ‌of‌ ‌the‌ ‌following‌ ‌conditions‌ before starting or during the treatment with ‌Tromit 30mg/ml Injection 1 ml:‌ 

  • Tromit 30mg/ml Injection 1 ml must be given to elderly patients with caution especially those with health conditions
  • Tromit 30mg/ml Injection 1 ml should not be used in pregnancy especially late in pregnancy for it may compromise fetal circulation or cause anomalies
  • If there is a history of gastrointestinal diseases such as colitis, or ulcers, it may put you at risk of gastric bleeding
  • If you are on anticoagulants, taking Tromit 30mg/ml Injection 1 ml may also put you at risk of bleeding since it delays clotting
  • Tromit 30mg/ml Injection 1 ml must not be administered before or during the surgery, it can cause hemorrhage
  • Patients with SLE or similar disorders may be at risk of aseptic meningitis
  • Caution is advised in patients with renal disease (if at all prescribed), liver impairment, or patients on diuretics, there’s a risk of developing dose-dependent renal failure in these patients
  • In women trying to conceive,  Tromit 30mg/ml Injection 1 ml may impair fertility hence not recommended
  • Tromit 30mg/ml Injection 1 ml can raise blood pressure, thereby regular monitoring of blood pressure is advised

Interaction with other medications

Certain medications could interact with Tromit 30mg/ml Injection 1 ml and may increase or decrease its absorption, in which case, your doctor might alter your dosage. A few of these interacting drugs are given below:

  • Anticoagulants such as clopidogrel, heparin
  • Diuretics such as furosemide 
  • ACE Inhibitors such as lisinopril, captopril
  • Corticosteroids 
  • Other NSAIDs like ibuprofen (may potentiate side effects)
  • Angiotensin receptor blockers such as candesartan

Adverse effects

Like most medicines, Tromit 30mg/ml Injection 1 ml has some side effects which include:

Common Side effects

  • Nausea 
  • Headache 
  • Vomiting 
  • Diarrhea /constipation
  • Pain at the injection site
  • Abdominal pain
  • Drowsiness 
  • Dizziness 

Rare side effects

  • Anaphylactic reaction 
  • Blurred vision
  • Fatigue 
  • fever/ chills
  • Raised blood pressure
  • Dark urine
  • Muscle or joint stiffness 
  • Bloody diarrhea
  • Arrhythmias 
  • Swelling of ankles
  • Paleness of skin
  • Palpitations 
  • Difficulty in breathing 

LIST OF HOW TO DEAL WITH ADVERSE EFFECTS

  • Fatigue- Patients experiencing this adverse effect are advised to take deep breaths, intake tea or coffee, get a good night’s rest, and not overburden themselves for a few days.
  • Feeling drowsy – If the medication makes you feel drowsy or sleepy, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Headaches- In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
  • Feeling or being sick (nausea or vomiting) or diarrhea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water.
  • Feeling dizzy (lightheaded) or weak –If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Muscular Aches and Pains- A hot or cold compress can be placed at the area of discomfort to bring relief; an over-the-counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.
  • Constipation- Can be combated by adding more fibers to the patient’s diet, asking the patient to drink plenty of fluids, and increasing their physical activity to trigger contractions in the intestines.
  • Flatulence- This can be eased by consuming smaller, more frequent meals that don’t trigger your flatulence. Getting a minimum of 30 minutes of daily exercise has shown great results in combating flatulence. 
  • Heartburn – can be dealt with by chewing on mint-flavored gum that’ll help neutralize the acid in the body. Standing up straighter, adding ginger to the daily diet, elevating the patient’s upper body, and having licorice supplements has shown to provide relief.
  • Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash
  • Blurred vision-  This side effect tends to go away on its own if a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.
  • Soreness at the site of injection- a cold compress can be used for 5 minutes to ease out the soreness.
  • Redness Of the Skin- This can be combated by applying a cold pack to the affected area.
  • Fever- patients are asked to ingest over-the-counter painkillers (such as Paracetamol), partake in plenty of fluids, and rest for a couple of days till the symptoms pass

Key facts 

  • Tromit 30mg/ml Injection 1 ml is prescribed to adults for the treatment of moderate to severe pain
  • Tromit 30mg/ml Injection 1 ml belongs to a group of medicines called NSAIDs commonly known as analgesics
  • Tromit 30mg/ml Injection 1 ml is chemically composed of ketorolac tromethamine
  • Tromit 30mg/ml Injection 1 ml is prescribed for short-term pain relief only
  • Tromit 30mg/ml Injection 1 ml is not prescribed to pregnant or lactating women or children/adolescents below 17 years
  • Tromit 30mg/ml Injection 1 ml is prescribed to be administered as an IV or IM injection
  • Tromit 30mg/ml Injection 1 ml may cause common side effects such as stomach problems, vomiting, nausea, drowsiness, and dizziness
  • Tromit 30mg/ml Injection 1 ml is not recommended for people with a history of gastric ulceration/bleeding

FAQs

#1 .HOW TO STORE Tromit 30mg/ml Injection 1 ml?

Tromit 30mg/ml Injection 1 ml is to be kept away from the reach of children, in a cool dry place, do not freeze, away from direct sunlight and humidity as that tends to ruin the chemical nature of certain drugs.

#2. WHAT IF I TAKE TOO MUCH OF Tromit 30mg/ml Injection 1 ml?

In case of too much consumption by accident, kindly contact your doctor or nearby hospital right away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing, bleeding tendencies accompanied by dizziness, and fainting spells.

#3. WHAT IF I MISS A DOSE OF Tromit 30mg/ml Injection 1 ml?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next dosage time or the next day, do not double the dose and take your medication as per schedule.

#4. HOW IS Tromit 30mg/ml Injection 1 ml SUPPOSED TO BE TAKEN?

Tromit 30mg/ml Injection 1 ml is taken orally preferably after a meal, in doses prescribed by your doctor. Usually, it is taken 2-3 times daily at a 6-8 interval OR as a single shot under the doctor’s supervision.

#5 .WILL Tromit 30mg/ml Injection 1 ml AFFECT MY SEXUAL ACTIVITY?

No, there isn’t sufficient evidence to suggest that patients experience a decrease in libido.

#6. CAN I TAKE Tromit 30mg/ml Injection 1 ml DURING MY PREGNANCY?

No, Tromit 30mg/ml Injection 1 ml is deemed unsafe to be ingested during pregnancy. Consult your doctor first. 

#7. WILL Tromit 30mg/ml Injection 1 ml AFFECT MY FERTILITY??

There are concerns that Tromit 30mg/ml Injection 1 ml may impair fertility. It is advised to consult your doctor regarding safety.

#8. IS IT SAFE TO HAVE PAINKILLERS WHILE TAKING Tromit 30mg/ml Injection 1 ml?

Tromit 30mg/ml Injection 1 ml is an analgesic itself. Painkillers are mostly NSAIDs like Tromit 30mg/ml Injection 1 ml. Concomitant use of other analgesics may potentiate the side effects, caution is advised.

#9. IS IT SAFE TO HAVE ANTACIDS FOR INDIGESTION ALONG WITH Tromit 30mg/ml Injection 1 ml?

To cure side effects like indigestion and heartburn due to  Tromit 30mg/ml Injection 1 ml you can take antacids but do consult your doctor as well.

#10. CAN Tromit 30mg/ml Injection 1 ml CAUSE DIZZINESS? IF SO, HOW SHOULD I MANAGE IT?

Yes. It can cause dizziness as one of the side effects. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. 

#11. DOES Tromit 30mg/ml Injection 1 ml CAUSE ADDICTION?

No, this drug has shown no evidence to prove addiction or dependence of any kind in any patient.

#12. HOW LONG WILL I HAVE TO CONTINUE TAKING THE MEDICATION?

It is a long-term treatment, and you might have to continue taking the medication for a few months or as advised by the doctor

#13. WHAT IF I FORGET TO TAKE THE Tromit 30mg/ml Injection 1 ml?

Tromit 30mg/ml Injection 1 ml is usually administered in a hospital setting. It is advised that the drug is taken at the same time each day, and an alarm can be placed to remind patients to take Tromit 30mg/ml Injection 1 ml at the proper time and at least an hour before having any meal. If the patient misses a dose of Tromit 30mg/ml Injection 1 ml, they should take it immediately but if the time for the next dose of the drug is near then it’s beneficial for patients to skip the missed dose and take the tablets as per schedule, doubling of doses has proven to cause severe side effects.

#14.  CAN I DRIVE AFTER TAKING THIS MEDICATION?

Tromit 30mg/ml Injection 1 ml can make you dizzy or drowsy in which case avoid driving or operating any heavy machinery

#15. WHAT IS Tromit 30mg/ml Injection 1 ml COMPOSED OF?

Tromit 30mg/ml Injection 1 ml is composed of ketorolac tromethamine (NSAIDs).