Nomit 10mg Tablet 10’S
Nomit 10mg Tablet 10’S is prescribed to treat discomfort caused by stomach problems such as nausea and vomiting
Nomit 10mg Tablet 10’S is also prescribed to ease the after-effects of chemotherapy
Nomit 10mg Tablet 10’S contains Domperidone Maleate
Nomit 10mg Tablet 10’S is to be ingested orally (via mouth)
Domperidone Maleate 10 mg
Chas. A. Mendoza
How to use, Side effects, Uses, Formula & Composition
Dopamine is one of the most important neurotransmitters involved in several natural mechanisms. The gastric tract also releases dopamine from the stomach and influences GIT from its upper to the lower part. Nomit 10mg Tablet 10’S belongs to a class of drugs called “dopamine receptor antagonists”, commonly referred to as anti-emetics used for the prevention and management of nauseous states. It also helps relieve symptoms of gastroparesis, a health condition that affects the stomach and normal bowel movements resulting in indigestion, nausea, and vomiting. Where it helps ease the symptoms, it also carries a high risk of serious side effects on the heart, for which reason it is disapproved in some countries like the USA, so caution is advised
Nomit 10mg Tablet 10’S is chemically composed of Domperidone which works by blocking the action of dopamine (D2 and D3 receptors) and enhances the effects of acetylcholine in the gastric tract, the outcome of which is manifested in form of enhanced gastric movement and digestion as well as increased pressure in the lower part of the esophagus that helps prevent reflux of stomach contents. Through its action on the brain, it helps control vomiting too. Nomit 10mg Tablet 10’S takes about 30 minutes to 1 hour to start working.
Nomit 10mg Tablet 10’S is available in the form of oral tablets on prescription to be swallowed via mouth with a glass of water, 1 tablet usually 2 to 3 times a day or as advised by the doctor. Do not crush or chew the tablet. It works better if you take it at least 30 minutes before your meal. Nomit 10mg Tablet 10’S can be safely prescribed to adults and children above 12 years of age. In case of pregnancy and lactation, ask your doctor first due to potentially harmful effects on the unborn baby. The most common side effects observed with Nomit 10mg Tablet 10’S are drowsiness, diarrhea, loss of appetite, dry mouth, etc.
Nomit 10mg Tablet 10’S is prescribed to children (above 12 years) and adults to treat:
- Epigastric pain
- Management of nausea/vomiting in patients on palliative care
How does Nomit 10mg Tablet 10’S work
Nomit 10mg Tablet 10’S is chemically composed of Domperidone which works by blocking the action of dopamine (D2 and D3 receptors) and enhances the effects of acetylcholine in the gastric tract, the outcome of which is manifested in form of enhanced gastric movement and digestion as well as increased pressure in the lower part of the food pipe (esophagus) that helps prevent reflux of stomach contents. . Nomit 10mg Tablet 10’S influences the chemoreceptor trigger zone present in the brain that regulates vomiting.
How to use Nomit 10mg Tablet 10’S
Nomit 10mg Tablet 10’S is available in the form of oral tablets. Swallow the tablet with a glass of water without chewing 15 to 30 minutes before taking a meal. Nomit 10mg Tablet 10’S is preferably taken at the same time every day till the prescribed time to maintain equal blood levels at all times. Nomit 10mg Tablet 10’S is taken orally in tablet form as per recommended doses. It is usually taken
2 – 3 times a day at 8 to 12 hourly intervals before a meal. Nomit 10mg Tablet 10’S should be taken at a set time and for the prescribed length of time, not exceeding it. The patient in general starts to feel better in a couple of days, make sure to complete the entire course even if you feel better. Treatment must not last longer than 7 days.
Available Potency of Nomit 10mg Tablet 10’S
- 5 mg – Tablet
- 10 mg – Tablet
- 12.7 mg – Tablet
1 tablet (10 mg) taken orally 3 times per day, before meals 15 to 20 minutes earlier
Not recommended for children under 12 years of age.
For children and adolescents above 12 years of age: 1 tablet (10 mg) taken orally 3 times per day, before meals 15 to 20 minutes earlier.
The exact dose must be determined by your doctor, ideally being the lowest effective due to serious heart side effects which may be more pronounced in elderly patients. Especially those taking any other medication concurrently. Seek a doctor’s advice.
Pregnancy Use and Lactation
Nomit 10mg Tablet 10’S is classified as a pregnancy category B drug by FDA (meaning no evidence of any risk in controlled animal trials but regarding the human fetus, insufficient data is available). It is advised if you are pregnant or are planning to conceive, please consult your doctor before using Nomit 10mg Tablet 10’S. Nomit 10mg Tablet 10’S is also secreted in human milk in little amount, if you are breastfeeding, please consult your doctor before taking Nomit 10mg Tablet 10’S.
Please inform your doctor if you have a history of any before using Nomit 10mg Tablet 10’S:
- Allergic reaction to Nomit 10mg Tablet 10’S or similar drugs
- Severe Liver disease
- History of serious heart disease
- Heart failure
- Prolonged corrected QT interval
- Hypo or hyperkalemia
- Low blood magnesium
- Unexplained Black tarry stool or blood in stool
- Bleeding from intestines
- Blocked intestines in conditions like diverticulitis, Crohn’s disease
- Underweight patients (less than 35 kgs)
- Patients under 12 years of age
Please tell your doctor about any of the following conditions before starting or during the treatment with Nomit 10mg Tablet 10’S:
- Make sure to rule out any allergies to Nomit 10mg Tablet 10’S or any similar drug
- Nomit 10mg Tablet 10’S works better if taken 15 to 30 minutes before a meal. Taking it after the meal will slow down its function
- Compromised liver function can negatively affect your body since Nomit 10mg Tablet 10’S is largely processed in it, discuss it with your doctor.
- Ensure adequate kidney function before using Nomit 10mg Tablet 10’S
- Elderly patients (65 years and above) should exercise caution if prescribed Nomit 10mg Tablet 10’S, especially if they are feeble and have a history of heart condition or taking doses of more than 30 mg per day
- Patients suffering from chronic gut disease must be careful, especially those with a history or an existing Gastrointestinal Perforation/ bleeding must avoid it
- Alcohol consumption may potentiate the side effects, it must be avoided or restricted with Nomit 10mg Tablet 10’S
- If you are taking medicines for conditions affecting heart rhythm or other, especially those that prolong the QTC interval, you should not take Nomit 10mg Tablet 10’S
- Treatment with Nomit 10mg Tablet 10’S usually proceeds with a minimal dose able to give clinical benefits, caution is advised if the dose exceeds more than 30 mg per day in adults/ adolescents or children
- If you are pregnant or lactating mother, consult a doctor first to determine if Nomit 10mg Tablet 10’S is safe for you.
- Nomit 10mg Tablet 10’S is known to cause increased levels of the hormone prolactin in the body. Rule out the presence of any tumor (such as prolactinoma or pituitary gland tumor)
Interaction With Other Medications
Following drugs can have some interactions with Nomit 10mg Tablet 10’S and can potentiate or reduce the effects when used concomitantly. Some of these drugs are:
- Azole antifungals ketoconazole, fluconazole
- Calcium channel blockers like verapamil, diltiazem
- Macrolide antibiotics like erythromycin, clarithromycin
- Antiarrhythmic drugs like quinidine, disopyramide
- Antidepressants like citalopram, escitalopram
- Antipsychosis or schizophrenia-like haloperidol, pimozide
- Gastric drugs cisapride, dolasetron
- Anti- HIV drugs
- Chemotherapeutic agents like toremifene
- Anti histamines like mequitazine
Like most medicines, Nomit 10mg Tablet 10’S has some side effects which include:
Common Side effects:
- Constipation /Diarrhea
- Dry mouth
- Skin rash
- Abdominal cramps
Rare side effects:
- Anaphylactic reaction
- Blurred vision
- Restlessness/ agitation
- Loss of appetite
- Uncontrolled eye movement
- Inability to urinate (urinary retention)
- Breast tenderness
- Milk secretion from breasts
- Disturbance in the menstrual cycle
- Low sex drive
- Changes in LFTs
HOW TO COPE-UP WITH SOME ADVERSE EFFECTS
Dry Mouth – Can be helped by sipping water throughout the day, chewing sugarless gum, using alcohol-free mouthwash, allowing ice to melt in the mouth, or using a saliva substitute.
Headaches – In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
Skin Rash – Can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. Antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.
Constipation – Can be combated by adding more fibers to the patient’s diet, asking the patient to drink plenty of fluids, and increasing their physical activity to trigger contractions in the intestines.
#1. WHAT EXACTLY DOES Nomit 10mg Tablet 10’S DO?
Nomit 10mg Tablet 10’S helps relieve symptoms of nausea, vomiting, and sickness. It works by blocking the effects of specific dopamine neurotransmitters (D2, D3) resulting in enhanced gastric movement and digestion and also helps prevent gastric reflux.
#2. HOW LONG WILL I HAVE TO TAKE Nomit 10mg Tablet 10’S FOR?
Nomit 10mg Tablet 10’S is usually taken for short treatment not exceeding 1 week and not a long-term course
#3. HOW LONG DOES IT TAKE FOR Nomit 10mg Tablet 10’S TO START WORKING?
The onset of action normally starts working within 30 minutes to 1 hour of ingestion
#4. CAN I STOP TAKING Nomit 10mg Tablet 10’S?
Consult your doctor for the exact time you are supposed to take Nomit 10mg Tablet 10’S and stop it after professional advice
#5. WHAT IF I TAKE TOO MUCH OF Nomit 10mg Tablet 10’S?
If you have taken too much of the prescribed Nomit 10mg Tablet 10’S you may experience symptoms of overdose, for example, fast pounding, irregular heartbeat, upset stomach, blurred vision, fainting, dizziness, seizures, or life-threatening severe symptoms. Contact your doctor immediately and rush to a nearby hospital if you have any of these symptoms. toxicity can be fatal if left unattended.
#6. WHAT IF I FORGET TO TAKE Nomit 10mg Tablet 10’S?
Nomit 10mg Tablet 10’S is taken 3 to 4 times a day before meals so you can take the missed dose as soon as you remember unless it’s less than 8 hours until your next dose, in which case you should skip the missed dose. If it helps to remind you, set an alarm or use a pill organizer or a mobile application so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.
#7. CAN I TAKE Nomit 10mg Tablet 10’S DURING PREGNANCY OR BREASTFEEDING?
Nomit 10mg Tablet 10’S may have a safety concern for the unborn baby, hence not advised without a doctor’s consultation. If you are pregnant, think you may be pregnant, or are planning to conceive a baby, please consult your doctor before using Nomit 10mg Tablet 10’S. If you are breastfeeding, please consult your doctor before taking Nomit 10mg Tablet 10’S.
#8. HOW SHOULD Nomit 10mg Tablet 10’S BE STORED?
Store it at room temperature, away from excess heat, direct sunlight, and moisture. Make sure it is not consumed by pets, children, and other people. Dispose of the unused medicine.
#9. CAN I DRIVE OR RIDE A BIKE AFTER TAKING Nomit 10mg Tablet 10’S?
Usually Nomit 10mg Tablet 10’S is not known to cause dizziness but make sure you know how your body reacts while using Nomit 10mg Tablet 10’S’. Do not drive or use any machinery until you feel normal again.
#10. WILL Nomit 10mg Tablet 10’S AFFECT MY FERTILITY?
Although not very common but Nomit 10mg Tablet 10’S can create disturbance in the menstrual cycle which is reversible. High prolactin levels can cause problems in ovulation in women. Discuss it with your doctor.