Hitica 90mg Tablet 10 ‘S

Description

About

Hitica 90mg Tablet 10 ‘S belongs to a class of drugs called “antiplatelet agents”, commonly referred to as blood thinners used for the prevention of heart attacks and strokes. It helps decrease the chances of having another heart attack or stroke in patients who have a history of chronic heart disease or heart surgery by easing out the blood flow and circulation through blood vessels. Conditions benefiting from Hitica 90mg Tablet 10 ‘S include venous thrombocytosis, rheumatic disease, post-coronary artery bypass grafting surgery, stents, or used in combination with other agents such as aspirin for mechanical heart valves and high-risk patients.

Hitica 90mg Tablet 10 ‘S is chemically composed of Ticagrelor, which works by acting on a particular receptor on platelets involved in clotting and blocking its effects thereby preventing platelets from sticking together into a clot form. This lowers the chance of heart attack or stroke. According to the clinical situation {{product} may be prescribed in combination therapy with aspirin or another anticoagulant.

It is available on prescription as tablets to be taken orally with water usually twice a day or as prescribed. Dosage of Hitica 90mg Tablet 10 ‘S depends on age, the severity of the condition, patients’ response to the medicine, and their comorbidities. It is not recommended for children below 18 years of age. Common side effects of this medication are an increased tendency to bleed (you may have nosebleeds, unusually heavy periods, bleeding gums, or bruising), shortness of breath, and an upset stomach.

Indications

It can be used for the prevention of atherothrombotic episodes in patients suffering from:

• Myocardial infarction – heart attack (history of a previous attack),

• Acute ischemic – a blood clot that blocks the vessel in the brain 

• Established peripheral artery disease (narrowed arteries reducing blood flow to arms/legs)

• Primary prevention of coronary artery disease

• Device closure of an atrial septal defect (ASD) for at least six months

• Combination therapy with aspirin or warfarin for mechanical heart valves

• Unstable angina

• After percutaneous intervention with stents

• Rheumatic heart disease

How does Hitica 90mg Tablet 10 ‘S work?

Hitica 90mg Tablet 10 ‘S acts on receptors called “P2Y12” located on platelets and works by antagonizing its effects, decreasing the formation of blood clots by preventing platelets from sticking together into a clot form known as the “aggregation” phenomena. Thereby, lowering the chances of heart attack or stroke. 

How to use Hitica 90mg Tablet 10 ‘S ?

Hitica 90mg Tablet 10 ‘S is available as tablets. Hitica 90mg Tablet 10 ‘S is usually prescribed to be taken twice a day around the same time every day, with or without food. Take Hitica 90mg Tablet 10 ‘S as prescribed by your doctor. Do not chew or crush the tablet. The dose may initially be started on high potency and then reduced as clinical improvement is noticed.

Dosage

Adult Dose

 Acute Coronary Syndrome such as a sudden heart attack:

It is important to take blood thinners at least up to one year after a major episode of attack, stroke, or any other acute heart condition to avoid recurrence.

Loading dose: 180 mg orally, once

Maintenance dose: up to 1 year 90 mg orally, twice a day

Maintenance dose: (after 1 year of maintenance): 60 mg orally, twice a day

Coronary Artery Disease:

When there is no previous history of an attack or stroke, the patient is considered to be at high risk such as patients with Diabetes.

60 mg orally, twice a day (morning and evening)

In combination with aspirin 75-100 mg once daily

Transient ischemic attack (ischemic stroke):

To decrease the chances of stroke in high-risk patients. 

Loading dose: 180 mg Hitica 90mg Tablet 10 ‘S orally in combination with 300-325 mg aspirin 

Maintenance dose of Hitica 90mg Tablet 10 ‘S: up to 1 month 90 mg orally, twice a day

Maintenance dose of aspirin:  75-100 mg once daily

Pediatric Dose

Hitica 90mg Tablet 10 ‘S is not prescribed to children younger than 18 years of age due to safety concerns.

Elderly Dose

Caution is advised while using Hitica 90mg Tablet 10 ‘S in the elderly population. Strictly follow your doctor’s prescription.

Special Dose: 

• Caution is advised in case of severe liver impairment and renal dose. Consult your physician regarding dose adjustment

• Taking aspirin more than 100 mg alongside Hitica 90mg Tablet 10 ‘S can reduce the therapeutic effects of Hitica 90mg Tablet 10 ‘S, large doses of aspirin should be avoided when used concurrently

Pregnancy use and lactation

Hitica 90mg Tablet 10 ‘S contains Ticagrelor in its formulation which is classified as pregnancy category C (A known risk and malformations observed in the fetus during studies conducted on animals and lack of data in pregnant humans). Therefore, this drug should not be prescribed to expecting mothers due to unknown effects. Hitica 90mg Tablet 10 ‘S is secreted in human milk in small quantities but consult a doctor first regarding its safety in lactation. It should only be prescribed if considered necessary after consulting a doctor. 

Contraindications

Please tell your doctor if you have a history of any of the following before using Hitica 90mg Tablet 10 ‘S:

• Allergy to Hitica 90mg Tablet 10 ‘S or similar drugs

• Recent traumatic injury, currently bleeding or at risk to bleed

• History of intracranial bleeding (bleeding in the brain) 

• Bleeding stomach ulceration/ perforation

• Breathing problems such as asthma, chronic lung disease like COPD

• Bradycardia 

• Blood disorders such as hemophilia 

• Hyperuricemia or conditions such as gout

• Pregnancy 

• Children younger than 18 years of age

• Severe liver dysfunction

• Scheduled for surgery major or minor including dental treatment (within a week)

Precautions

Please tell your doctor about any of the following conditions before using Hitica 90mg Tablet 10 ‘S:

• Hitica 90mg Tablet 10 ‘S must be used with caution if you have a history of drug-related allergies

• In case of decreased liver function, Hitica 90mg Tablet 10 ‘S must not be used since it is taken up and processed in the liver. It can cause increased bleeding.

• If you suffer from blood disorders, make sure to discuss with your doctor first

• Avoid activities that are likely to cause injury or provoke bleeding while using Hitica 90mg Tablet 10 ‘S

• Hitica 90mg Tablet 10 ‘S can result in abnormal bleeding. Report to your doctor if you notice abnormal bleeding such as in stool, cough, vomit, nose, etc.

• Do not stop taking Hitica 90mg Tablet 10 ‘S without consulting a doctor

• In case you are scheduled for surgery (major or minor including dental treatment), after discussing with your doctor Hitica 90mg Tablet 10 ‘S should be stopped 5-7 days before surgery

• Alcohol intake should be restricted

• Do not take other blood thinners unless advised by your doctor

• Analgesics like aspirin, NSAIDs like ibuprofen, naproxen, etc. should be avoided with Hitica 90mg Tablet 10 ‘S, for it can evoke bleeding

• Hitica 90mg Tablet 10 ‘S is not considered safe for pregnant and lactating mothers. If it is advised during breastfeeding due to your condition, monitor your baby carefully for side effects

• Hitica 90mg Tablet 10 ‘S must be used with caution in patients with a history of blood uric acid 

• While undergoing tests, provide a list to your lab personnel

Interaction with other medications

Certain medications could interact with Hitica 90mg Tablet 10 ‘S some of which are enlisted below, hence, inform your doctor about the use of the CYP3A inhibitors or the following before taking Hitica 90mg Tablet 10 ‘S:

• Other P2Y12 antagonist anticoagulants

• Phenytoin

• Aspirin (more than 100 mg)

• Anti convulsant such as phenobarbital, Carbamazepine 

• Rifampicin 

• Digoxin 

• Cyclosporine

• Clarithromycin 

• Ketoconazole

• Quinidine 

• Calcium channel blockers like Diltiazem/verapamil

• Cholesterol controlling drugs like simvastatin, lovastatin 

• Antivirals like HIV drugs atazanavir, ritonavir etc

• Morphine, oxy/hydrocodone, and other opioids

• NSAIDs like naproxen, ibuprofen

• SSRI antidepressants like citalopram

Adverse effects

Like most medicines, Hitica 90mg Tablet 10 ‘S has some side effects which include:

Common side effects

• Prolonged /easy bleeding (you may have nosebleeds, heavier menses, bleeding gums) 

• Diarrhea

• Indigestion or heartburn

• Stomachache

• Shortness of breath 

• Easy bruising 

Less common side effects

• Hypersensitivity/allergic skin reactions; in this case, discontinue 

• Excessive bleeding episodes such as epistaxis, hemarthrosis

• Subcutaneous bleeding 

• Gastrointestinal (stomach and bowel) bleeding

• Hematoma (localized bleeding outside a blood vessel)

• Nervous system disorder

• Hepatic (liver) impairment

• Urinary tract bleeding

• Biliary disorder 

• Hematological (blood-related) disorders

• Rarely, thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels) and Stevens-Johnson syndrome (serious skin disorder of the skin or mucous membranes in reaction to medication).

How to cope with some of the adverse effects?

• Bleeding more easily than normal – Be cautious of taking part in activities that could result in an injury or a deep cut. Always wear a helmet while cycling, gloves while using sharp objects like scissors and knives, use an electric razor instead of wet shaving, a soft toothbrush while brushing, and waxed dental floss. Contact your doctor if more than normal bleeding occurs. 

• Diarrhea – Keep yourself hydrated by having lots of fluids and if the problem persists, consult your doctor before taking any medication for vomiting and diarrhea

• Indigestion/heartburn – Avoid food items that cause wind. Try having smaller and more frequent meals.

• Stomachache – Try to rest as much as possible and have smaller and more frequent meals. Using a heat pack or hot water bottle over the area in pain might help in giving some relief. If the pain persists and is severe, speak to your doctor.

Inform your doctor immediately if you experience any of the serious side effects.

FAQs

#1. What Exactly Does Hitica 90mg Tablet 10 ‘S Do?

It is an anticlotting agent, commonly referred to as blood thinners used for the prevention of heart attacks and strokes. It helps decrease the chances of having another heart attack or stroke in patients who have a history of heart disease. Hitica 90mg Tablet 10 ‘S works by decreasing the formation of blood clots by preventing platelets from sticking together. Thereby, lowering the chances of heart attack or stroke.

#2. How Long Does It Take For Hitica 90mg Tablet 10 ‘S To Start Working?

Hitica 90mg Tablet 10 ‘S starts working within 1 hour of taking it. 

#3. How Long Will I Have to Take Hitica 90mg Tablet 10 ‘S For?

The duration for using Hitica 90mg Tablet 10 ‘S depends on the severity of your condition. It is commonly prescribed for up to one year, or you may have to take it for a longer period as prescribed by your doctor. 

#4. Can I Stop Taking Hitica 90mg Tablet 10 ‘S?

Do not just stop taking the medicine, make sure to complete your treatment even if you feel better. Stopping it will put you at a higher risk of serious problems like heart attacks or strokes. 

#5. Can I Drink Alcohol With Hitica 90mg Tablet 10 ‘S?

Yes, but taking it in excess can damage your liver and stomach. Avoid consuming alcohol in large amounts when taking Hitica 90mg Tablet 10 ‘S to prevent the risk of stomach problems.

#6. What If I Take Too Much Of Hitica 90mg Tablet 10 ‘S?

If you have accidentally taken 1 or 2 extra tablets, it is unlikely to cause serious harm to you but the amount of Hitica 90mg Tablet 10 ‘S that can lead to overdose varies from person to person. Hence, contact your doctor immediately if you have taken extra tablets and notice any sign of bleeding. 

#7. What If I Forget to Take Hitica 90mg Tablet 10 ‘S?

In case you miss a dose, take your next dose on time and do not try making up for the missed dose by doubling it up. If it helps to remind you, set an alarm so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

#8. Can I Take Hitica 90mg Tablet 10 ‘S During Pregnancy or Breastfeeding?

If you are pregnant or are planning to have a baby, please consult your doctor before using Hitica 90mg Tablet 10 ‘S as it is contraindicated unless considered necessary.

If you are breastfeeding, please consult your doctor before taking Hitica 90mg Tablet 10 ‘S as it may pose a risk to your baby.

#9. How Does Hitica 90mg Tablet 10 ‘S Compare with Other Antiplatelet Medicines Like clopidogrel?

Clopidogrel prevents blood clots and future heart attacks or stroke (if you have already had one) but Hitica 90mg Tablet 10 ‘S is not approved to prevent further strokes (if you have already had one). Hitica 90mg Tablet 10 ‘S is usually taken twice a day unlike clopidogrel which is taken once a day and Hitica 90mg Tablet 10 ‘S is known to cause more bleeding when compared to ticagrelor. 

#10. Is It Safe to Use Hitica 90mg Tablet 10 ‘S For A Long Time?

Hitica 90mg Tablet 10 ‘S is generally safe to take for a long time. It works best if you take it for many months or even years. At times it may result in a stomach ulcer, but for that, your doctor may prescribe a medicine to help prevent any ulcers from forming while taking Hitica 90mg Tablet 10 ‘S. 

#11. Will I Have to Stop Taking Hitica 90mg Tablet 10 ‘S Before Surgery Or Dental Treatment?

Do not stop taking Hitica 90mg Tablet 10 ‘S without consulting with your doctor or dentist. You will be informed if you need to stop taking it before any procedure. You might be advised to stop taking it for a short time before a procedure because of the risk of bleeding. 

#12. Can I Drive or Ride A Bike After Taking Hitica 90mg Tablet 10 ‘S?

Hitica 90mg Tablet 10 ‘S doesn’t affect your concentration, so you can drive or ride a bike while you’re taking it. If you are feeling unwell avoid such activities.

#13. How Should Hitica 90mg Tablet 10 ‘S Be Stored?

Keep the medicine at room temperature in a cool, dry place, away from direct sunlight. Make sure it is not consumed by pets, children, and other people. Dispose of unused medicine when it is expired or no longer needed. 

#14. Will It Affect My Menstrual Cycle?

There is an increased tendency to bleed. Few women may experience heavier periods or vaginal bleeding. Report to your doctor if you notice this.

#15. Can I Take Painkillers With Hitica 90mg Tablet 10 ‘S?

NSAIDs like ibuprofen, naproxen which are likely to cause bleeding should be avoided. For pain relief, Paracetamol (acetaminophen) can be taken while treatment.

#16. Is There Any Food Product I Need to Avoid With Hitica 90mg Tablet 10 ‘S?

It is recommended to avoid taking grapefruit juice or grapefruit with Hitica 90mg Tablet 10 ‘S