Pladex-5 D5W 5% Injection 1000 ml

Description

About

Low blood sugar levels can have fatal consequences if not treated on time. Dextrose is a carbohydrate that is similar to glucose. Pladex-5 D5W 5% Injection 1000 ml is an intravenous drug that belongs to a class of medicines known as “Hyperglycemic” used to treat low blood sugar levels, especially diabetic patients on insulin, dehydration, and maintenance of electrolyte levels in patients without nutritional intake via mouths such as comatose patients or bowel obstruction (in which case to ensure adequate caloric intake it is combined with proteins or fats – “Total parenteral intake”), and other conditions. Pladex-5 D5W 5% Injection 1000 ml is strictly administered under doctor’s supervision after careful assessment of blood sugar levels, symptoms of hypoglycemia and treatment needs of the patient. 

Pladex-5 D5W 5% Injection 1000 ml contains Dextrose as its constituent, which is an IV caloric supplement that works with immediate effect after administration. It is processed into water and carbon dioxide to restore the caloric balance and water needs in the body. Besides it also helps in reducing the consumption of stored glucose in the form of glycogen and utilizes sources other than protein for energy derivation.  Frequent monitoring of blood glucose is required to avoid hyperglycemia and other possible adverse effects.

Pladex-5 D5W 5% Injection 1000 ml is available in a sterile plastic container to be administered via slow IV infusion at a predetermined infusion rate of mL per hour. It is to be administered by a healthcare professional and can also be diluted with other injectable solutions matching the compatibility with Pladex-5 D5W 5% Injection 1000 ml. The rate of infusion (ml/hr) of Pladex-5 D5W 5% Injection 1000 ml is dependent on the patient’s age, weight, blood sugar levels, medical condition, and concurrent treatment. The safety of Pladex-5 D5W 5% Injection 1000 ml in pregnant and lactating females is to be established by a doctor who will only prescribe it if considered necessary. Most common side effects observed with Pladex-5 D5W 5% Injection 1000 ml include phlebitis, shivering, fever, polydipsia, hyperglycemia, etc. 

Indications

Pladex-5 D5W 5% Injection 1000 ml is prescribed for the management of :

• Hypoglycemia 
• Hyperkalemia 
• Acute alcohol intoxication 
• Insulin-induced hypoglycemia 

How Does Pladex-5 D5W 5% Injection 1000 ml Work

Pladex-5 D5W 5% Injection 1000 ml is chemically composed of Dextrose, a carbohydrate that is similar to glucose. It is processed into water and carbon dioxide to restore the caloric balance and water needs in the body. It also helps in reducing the consumption of stored glucose in the form of glycogen and utilizes sources other than protein for energy derivation. 

How To Use {{Product}}

• Pladex-5 D5W 5% Injection 1000 ml is injected into the patient’s vein by a trained healthcare professional in a hospital. The area where the needle is to pierce the skin is first disinfected with an alcohol swab or any other disinfectant that the hospital has.
• Then the needle is uncapped and inserted into the vein and attached with sterile taping to keep it in place
• Carefully inspect the container of Pladex-5 D5W 5% Injection 1000 ml to ensure sterility of solution, intact seal, and clarity of the solution. 
• Once ensured, open the IV infusion kit with aseptic measures and remove the rubber stopper at the bottom part of the container, insert the device needle into the port. 
• Flush out some fluid to remove any air bubbles in the pipes. Connect the pipe with the patient’s cannula and suspend the container from a stand. 
• Rate of infusion is adjusted through a valve attached to the infusion pipes to increase or decrease the amount of solution being injected.  The solution is injected slowly in mL per hour.
• Pladex-5 D5W 5% Injection 1000 ml can also be diluted with other injectable solutions matching the compatibility which should be done before starting the infusion process.
• The area of the skin where the needle enters, may become slightly bruised or remain sore for 24 hours. After the injection the needle prick is pressed down (by hand) for 20 seconds, to make sure there is no bleeding and then a band-aid is placed on top. 

Dosage

Pladex-5 D5W 5% Injection 1000 ml dosage, frequency, and rate are determined by the doctor in charge. Pre administration blood samples are collected to assess the blood glucose to calculate the actual amount of infusion required. Dosage and rate of infusion are calculated for each individual, by health care professionals, depending upon the patient’s medical condition, the reason for administering Pladex-5 D5W 5% Injection 1000 ml as well as the patient’s weight and age.

In case of acute symptoms of a hypoglycemia IV bolus of Pladex-5 D5W 5% Injection 1000 ml may be injected to be followed by maintenance via slow infusion where needed. Precaution needs to be taken before administering Pladex-5 D5W 5% Injection 1000 ml to patients aged above 60 years and also to infants as due to slow kidney functions, sodium may be retained for a longer time than needed in the body.

As a general rule, the safe amount of dextrose that can be infused without hyperglycemia/glycosuria is 0.5 g/kg of body weight /hr. Too rapid infusion can create serious problems 

Pregnancy Use And Lactation

Pladex-5 D5W 5% Injection 1000 ml falls under FDA pregnancy category C which means it should not be taken during pregnancy due to unestablished effects on unborn babies. Therefore, if you are pregnant, or are planning to conceive a baby, consult a doctor who will only prescribe it if necessary. 

If you are breastfeeding an infant tell your doctor first, the amount of medicine secreted into breast milk is unclear. With regards to safety please make sure to consult your doctor first before using it. 

Contraindications

Please tell your doctor if you have a history of any of the following before using Pladex-5 D5W 5% Injection 1000 ml:

• Allergy to corn or corn products
• Intracranial hemorrhage 
• Blood sugar greater than 60 mg/dl 
• Hyperglycemia 
• Hyperosmolar coma
• Severe dehydration (avoid hypertonic dextrose)
• Anuria 
• Hypokalemia 

Precautions‌ ‌

Please‌ ‌tell‌ ‌your‌ ‌doctor‌ ‌about‌ ‌any‌ ‌of‌ ‌the‌ ‌following‌ ‌conditions‌ before starting or during the treatment with ‌Pladex-5 D5W 5% Injection 1000 ml:‌ 

• If there is a history of allergy to medicines or products that are corn or its derivatives. Carefully read the contents of this product to avoid any future inconvenience 
• Carefully inspect the container of Pladex-5 D5W 5% Injection 1000 ml to ensure sterility of solution and intact seal and clarity of the solution 
• ‌Pladex-5 D5W 5% Injection 1000 ml is preferably administered via slow IV infusion to avoid hyperosmolar syndrome from a very quick infusion 
• ‌Pladex-5 D5W 5% Injection 1000 ml is to be administered into the patient’s veins exclusively and not into the muscles or underneath the skin
• Patient must be informed about the possibility of phlebitis at the site of injection, healthcare professionals should try to utilize large central veins for inserting a cannula and resort to an adequate dilution method
• A new, sterile syringe/ cannula must always be used and properly discarded following universal protocol for sharps disposal
• Monitoring of blood sugar levels, blood pressure, pulse, and respiratory rate are advised 
• Ensure monitoring of ‌Pladex-5 D5W 5% Injection 1000 ml infusion as strictly prescribed. Taking more than required dextrose can cause hypokalemia and hyperglycemia
• Caution is advised while injecting in infants and newborns especially with low birth weights to avoid high serum osmolality
• Watch out for the signs of peripheral and pulmonary edema 
• Pregnant and breastfeeding mothers must not use Pladex-5 D5W 5% Injection 1000 ml without a doctor’s supervision
• Discuss with your doctor your history of heart diseases, kidney and liver function
• History of head injury should be taken into account before administering Pladex-5 D5W 5% Injection 1000 ml
• If Pladex-5 D5W 5% Injection 1000 ml is being infused into a newborn baby with a diabetic mother, caution is advised. Determine the blood glucose levels first to avoid hyperglycemia
• Newborn infants with low birth rates are also at risk of side effects due to inadequate kidney function, take precautions accordingly
• Aluminum may be present in some formulations of dextrose, check with your doctor. If ‌Pladex-5 D5W 5% Injection 1000 ml is used for a longer duration, it runs a risk of aluminum toxicity

Interaction With Other Medicines

Pladex-5 D5W 5% Injection 1000 ml is generally safe to use since it is used as an energy source. Sometimes Pladex-5 D5W 5% Injection 1000 ml is diluted by the addition of other fluids. The compatibility of these fluids must be ensured to avoid any inconvenience.

Always provide a complete list of medicines you are talking to your doctor or healthcare provider to rule out any possible interaction you might have with Pladex-5 D5W 5% Injection 1000 ml 

Adverse Effects

  Common Side Effects

• Pain at the injection site 
• Constipation/diarrhea 
• Hyperglycemia 
• Headache
• Chills 
• Phlebitis 
• Lightheadedness 
• Skin rash/itching 

Less Common Side Effects

• Anaphylactic reaction
• Breathing difficulty 
• Hyperosmolar syndrome 
• Vomiting 
• Infection at the injection site 
• Peripheral edema 
• Venous thrombosis 
• Air embolism 
• Swelling of face, throat, limbs
• Fainting 
• Hyperkalemia 
• Nontraumatic neurological changes 
• Mental confusion 

 How To Deal With Some Adverse Effects

• Soreness at the site of injection- a cold compress can be used for 5 minutes to ease out the soreness.
• Allergic Reactions – Allergic reactions to the drug may be mild to severe or potentially could be life-threatening. If allergy is suspected immediately take anti-allergy (antihistamine) medicine which will stop the mild reaction. If a serious allergic reaction is suspected, rush to the nearby hospital and avoid Pladex-5 D5W 5% Injection 1000 ml and drugs with similar compounds in the future.
• Headaches – In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
• Constipation – Can be combated by adding more fibers to the patient’s diet, asking the patient to drink plenty of fluids, and increasing their physical activity to trigger contractions in the intestines.
• Feeling or being sick (nausea or vomiting) or diarrhea – Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. 
• Feeling dizzy (lightheaded) or weak – If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Skin Rash – Can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash helps reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash
• Muscular Aches And Pains – A hot or cold compress can be placed at the area of discomfort to bring relief; an over-the-counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.

FAQ’S

#1. WHAT EXACTLY DOES Pladex-5 D5W 5% Injection 1000 ml DO?

Pladex-5 D5W 5% Injection 1000 ml is an intravenous caloric supplement used to treat symptoms of low blood sugar. It is a carbohydrate that is similar to glucose. It helps in restoring caloric balance and water needs in the body. Besides, it also helps in reducing the consumption of stored glucose in form of glycogen and utilizes sources other than protein for energy derivation. 

#2. WHAT IF I TAKE TOO MUCH OF Pladex-5 D5W 5% Injection 1000 ml?

Pladex-5 D5W 5% Injection 1000 ml is administered via IV route in a hospital set up with monitoring of sugar levels, if there is an excess by chance your doctor will take care of it. If for some reason an IV line is being maintained at home by a healthcare provider, immediately inform the caretaker and contact your doctor or nearby hospital straight away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

#3. HOW TO USE Pladex-5 D5W 5% Injection 1000 ml?

Pladex-5 D5W 5% Injection 1000 ml is injected into the patient’s vein by a trained healthcare professional. The area where the needle of the cannula is to pierce the skin is first disinfected by an alcohol swab or any other disinfectant that the hospital has. Then the needle was uncapped and the solution was injected into the body. The solution is injected slowly via infusion over hours depending upon the amount that needs to be injected. The area of the skin where the needle enters may slightly bruise or remain sore for 24 hours. After the injection the needle prick is pressed down (by hand) for 20 seconds, to make sure there is no bleeding and then a band-aid is placed on top.

#4. CAN I TAKE Pladex-5 D5W 5% Injection 1000 ml DURING MY PREGNANCY?

This drug is not to be taken or prescribed to expecting and lactating mothers unless advised by the doctor. The safety data is not established for pregnant females, hence do not use it unless advised by your doctor.

#5. HOW TO STORE Pladex-5 D5W 5% Injection 1000 ml?

Pladex-5 D5W 5% Injection 1000 ml is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity at room temperature.

#6. WHAT LAB TESTS WILL BE PRESCRIBED WHILE TREATMENT WITH Pladex-5 D5W 5% Injection 1000 ml AND HOW OFTEN?

While Pladex-5 D5W 5% Injection 1000 ml is being administered via an IV line, regularly check Blood glucose levels to avoid hyperglycemia, as well as check serum potassium levels. Also monitor blood pressure, pulse, and respiratory rate. 

#7. WHAT IF I FORGET TO TAKE THE Pladex-5 D5W 5% Injection 1000 ml?

 Pladex-5 D5W 5% Injection 1000 ml is not self-administered in doses but is usually given as a single-use infusion throughout a specified time by a health professional so missing on a d is unlikely

#8. CAN Pladex-5 D5W 5% Injection 1000 ml CAUSE DIZZINESS? IF SO, HOW SHOULD I MANAGE IT?

Yes, It can cause dizziness as one of the most common side effects. If this happens, you should wait until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during your treatment, as it may worsen the dizziness.

#9. CAN I DRIVE AFTER TAKING THIS MEDICATION?

This medication is known to make you dizzy hence if that happens kindly avoid driving or operating any heavy machinery.

#10. IS Pladex-5 D5W 5% Injection 1000 ml SAFE TO GIVE TO CHILDREN?

Yes, Pladex-5 D5W 5% Injection 1000 ml can be given to infants and newborns but caution is advised while administering Pladex-5 D5W 5% Injection 1000 ml to infants especially with low birth weights to avoid side effects. Precautions should also be taken if the mothers of these infants are diabetic themselves.