Buzon Oral 1mg/ml Liquid 30 ml

Description

About

Buzon Oral 1mg/ml Liquid 30 ml belongs to a class of drugs called “atypical antipsychotics” (benzisoxazole derivative) used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder, irritability associated with autistic disorder).

Atypical antipsychotics (AAP) are also known as second-generation antipsychotics (SGAs) and serotonin-dopamine antagonists (SDAs) are a group of drugs (in general also known as major tranquilizers and neuroleptics) are used to treat psychiatric conditions.

It is available on prescription, as tablets, dispersible tablets, liquid, and long-acting injections. Buzon Oral 1mg/ml Liquid 30 ml works by altering the activity of chemical substances in the brain thereby reducing the symptoms of psychosis. Buzon Oral 1mg/ml Liquid 30 ml helps in shortening the recovery time and prevents relapses. 

Common side effects of this medication are nausea, vomiting, diarrhea, stomach ache, wind or loss of appetite, dizziness, headaches, and mild rash.

Dosage of Buzon Oral 1mg/ml Liquid 30 ml depends on age, the severity of the condition, patients’ response to the medicine, and their comorbidities. In children, it is also based on their weight. 

Indications

It is used in the treatment of:

• Symptoms of schizophrenia (a mental illness characterized by disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and teenagers 13 years of age and older.
• Episodes of mania (frenzied, abnormally excited, or irritated mood) or mixed episodes (symptoms of mania and depression that happen together) in adults and teenagers. 
• Bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods) in adults and children above 10 years of age. 
• Behavior problems such as aggression, self-injury, and sudden mood changes in teenagers and children between 5 to 16 years of age who have autism (a developmental disorder causing repetitive behavior, difficulty interacting with others, and communication problems)

How does Buzon Oral 1mg/ml Liquid 30 ml work

It is an atypical antipsychotic that works by altering the activity of chemical substances in the brain thereby reducing the symptoms of psychosis. Buzon Oral 1mg/ml Liquid 30 ml also helps in shortening the recovery time and prevents relapses. 

How to use Buzon Oral 1mg/ml Liquid 30 ml

• Buzon Oral 1mg/ml Liquid 30 ml is available as tablets, dispersible tablets/orally disintegrating tablets (tablets that dissolve quickly in the mouth), liquid, and long-acting injection. 
• Buzon Oral 1mg/ml Liquid 30 ml is usually prescribed to be taken once or twice a day with or without food at around the same time(s) every day. 
• Take Buzon Oral 1mg/ml Liquid 30 ml as prescribed by your doctor. 
• Use the dropper provided to measure your dose for oral solution. It can be taken with water, orange juice, coffee, or low-fat milk. Do not take the solution with tea or cola.
• Avoid pushing the orally disintegrating tablet through the foil. Instead, peel back the foil packaging using dry hands. Place the tablet on your tongue and it will quickly dissolve and can be swallowed with or without liquid. 
• Do not chew or crush the tablet.
• To allow your body to adjust to the medication, your doctor will probably start you on a low dose of risperidone and then gradually increase it with time. 

Dosage

Schizophrenia:

Adults 

• Initial dose: 2 mg       
• Titrations (increments): 1 to 2 mg     
• Target dose: 4 to 8 mg           
• Effective dose range: 4 to 16 mg

Adolescents    

• Initial dose: 0.5 mg
• Titration (increments):0.5 to 1 mg    
• Target dose: 3 mg      
• Effective dose range: 1 to 6 mg

Bipolar mania: 

Adults 

• Initial dose: 2 to 3 mg
• Titration (increments):  1 mg
• Target dose:  1 to 6 mg

Effective dose range: 1 to 6 mg

Children and adolescents

• Initial Dose: 0.5 mg    
• Titration (increments): 0.5 to 1 mg   
• Target dose:  1 to 2.5 mg       
• Effective dose range: 1 to 6 mg

Irritability in autistic disorder:

• Initial dose:  

       0.25 mg can increase to 0.5 mg by Day 4: (body weight less than 20 kg) 

       0.5 mg Can increase to 1 mg by Day 4: (body weight greater than or equal to 20 kg)   

• Titration (increments): After Day 4, at intervals of > 2 weeks: 

       0.25 mg (body weight less than 20 kg) 

       0.5 mg (body weight greater than or equal to 20 kg)     

• Target dose: 

        0.5 mg: (body weight less than 20 kg) 

        1 mg: (body weight greater than or equal to 20 kg)

• Effective dose range: 0.5 to 3 mg

Doses are modified accordingly if a patient has renal or hepatic impairment.

Pregnancy use and lactation

If you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor before using Buzon Oral 1mg/ml Liquid 30 ml as it is contraindicated.

If you are breastfeeding, please consult your doctor before taking Buzon Oral 1mg/ml Liquid 30 ml as it is contraindicated.

Contraindications

Please inform your doctor if you have a history of any before using Buzon Oral 1mg/ml Liquid 30 ml:

• Allergic reaction to Buzon Oral 1mg/ml Liquid 30 ml – indicated by skin rash, swelling around the face area, wheezing, chest tightness, and breathing difficulty

Precautions

Please tell your doctor about any of the following conditions while using Buzon Oral 1mg/ml Liquid 30 ml:

• Elderly
• Renal impairment
• Hepatic impairment
• Cardiovascular Disease
• Epilepsy
• Parkinsonism
• Dementia
• Hyperprolactinaemia
• Diabetes
• Bradycardia
• Hypokalaemia 
• Hypomagnesaemia
• Family history of QT prolongation. 
• Driving/Operating Machinery.
• Monitor for signs of tardive dyskinesia, withdraw if these occur. 
• Monitor for hyperglycemia and weight gain. 
• Risk factors for stroke 
• Monitor patients with a history of low WBC count or drug-induced leukopenia/neutropenia.
• Monitor endocrinological status, sedative effects, and the development of extrapyramidal symptoms and other movement disorders in children. Withdraw gradually.

Interaction with other medications

Certain medications could interact with Buzon Oral 1mg/ml Liquid 30 ml, hence, in that case, your doctor might alter your dosage and make sure to monitor blood sugar levels more closely.

Please inform your doctor about the use of the following before taking Buzon Oral 1mg/ml Liquid 30 ml:

• Centrally acting drugs like levodopa 
• Dopamine agonists
• Drugs that prolong QT interval
• Alcohol
• Antihistamines 
• Benzodiazepines 
• Antihypertensives
• Paliperidone
• Psychostimulants
• Paroxetine, fluoxetine, and other CYP2D6 inhibitors
• Itraconazole, ketoconazole, verapamil and other CYP3A4 and/or P-gp inhibitors and inducers
• Carbamazepine
• Rifampicin  
• Furosemide
• Anticholinergics

Adverse effects

Like most medicines, Buzon Oral 1mg/ml Liquid 30 ml has some side effects which include:

Common Adverse Effects

Following side effects may not require immediate medical attention until becomes troublesome:

• Nausea 

• Vomiting 
• Diarrhoea 
• Indigestion (stomach ache)
• Loss of appetite 
• Dizziness
• Headaches
• Mild rash

Rare Adverse Effects

Side effects to report to your doctor or health care provider as soon as possible include:

• Hypersensitivity/allergic skin reactions; in this case, discontinue
• Orthostatic hypotension
• Reflex tachycardia
• Extrapyramidal symptoms
• Menstrual disturbance
• Sexual dysfunction
• Insomnia
• Anxiety
• Agitation
• Impaired concentration
• Weight Gain
• Rhinitis
• Blurred Vision
• Depression
• Somnolence 
• Ear Infection 
• Dyspnoea 
• Epistaxis
• Cough 
• Nasal Congestion 
• Pharyngolaryngeal Pain 
• Dry Mouth
• Toothache 
• Priapism
• Urinary Incontinence, Urinary tract infections
• Tachycardia 
• Gynaecomastia
• Altered liver function tests
• Hyperglycaemia
• Hyperprolactinemia
• Anemia
• Conjunctivitis
• Asthenia
• Fatigue
• Muscle Spasm
• Musculoskeletal Pain
• Pain In Extremities
• Pyrexia
• Edema
• Chest Pain
• Flu-like Illness
• Rarely, Neuroleptic Malignant Syndrome
• Water Intoxication With Hyponatremia
• Seizures
• Tardive Dyskinesia
• Intraoperative Floppy Iris Syndrome

How To Cope With Some Of The Adverse Effects

• Nausea (feeling sick) – Take Buzon Oral 1mg/ml Liquid 30 ml with meals to avoid feeling sick.
• Vomiting/Diarrhoea – Keep yourself hydrated by having lots of fluids and if the problem persists, consult your doctor before taking any medication for vomiting and diarrhea
• Loss of appetite – Continue having your meals at times that you would usually have them. If it helps, decrease the portion of your meals and have them more frequently. Snack on high-protein food items like fruits and nuts. 
• Indigestion – Avoid food items that cause wind. Try having smaller and more frequent meals.
• Headache – Take a painkiller, rest, and keep yourself hydrated at all times. Contact your doctor if your headaches last more than a week and/or become severe.
• Dizziness – Try and rest until you feel better and refrain from driving or using any tools or machinery
• Mild rash – Use a cream or ointment to moisturize, soothe and hydrate the affected area. If it doesn’t get better in a week contact your doctor.

Inform your doctor immediately if you experience any of the serious side effects.

Key Facts 

• {{Product}} belongs to a class of drugs called “atypical antipsychotics” (benzisoxazole derivative) used to treat certain mental/mood disorders (such as bipolar disorder, schizophrenia, irritability associated with autistic disorder).

• Atypical antipsychotics (AAP) are also known as second-generation antipsychotics (SGAs) and serotonin-dopamine antagonists (SDAs) are a group of drugs (in general also known as major tranquilizers and neuroleptics) are used to treat psychiatric conditions.
• It is prescribed to adults and children.
• {{Product}} should be taken with food or milk to prevent upset stomach
• It is available as tablets, dispersible tablets/orally disintegrating tablets (tablets that dissolve quickly in the mouth), liquid, and long-acting injection. 
• It may take up to 4-6 weeks for the medicine to start showing significant effects. 
• Common side effects of this medication are nausea, vomiting, diarrhea, stomach ache, wind or loss of appetite, dizziness, headaches, and mild rash.
• It may cause excessive drowsiness and increase your risk of stomach problems if you consume alcohol while taking Buzon Oral 1mg/ml Liquid 30 ml.
• It may cause an increase in weight, blood sugar, cholesterol, and fat. Eat healthy, exercise, and monitor your levels regularly.
• A matter of concern arises if you get a rash, itchy skin, swelling on the face, and difficulty breathing, in which case you need to inform your doctor immediately. 

FAQs

#1. What exactly does Buzon Oral 1mg/ml Liquid 30 ml do?

It is an atypical antipsychotic that works by altering the activity of chemical substances in the brain thereby reducing the symptoms of psychosis. Buzon Oral 1mg/ml Liquid 30 ml also helps in shortening the recovery time and prevents relapses. 

#2. How long does it take for Buzon Oral 1mg/ml Liquid 30 ml to start working?

It may take up to 4-6 weeks for the medicine to start showing significant effects. Keep taking Buzon Oral 1mg/ml Liquid 30 ml as prescribed. 

#3. How long will I have to take Buzon Oral 1mg/ml Liquid 30 ml for?

The duration for using Buzon Oral 1mg/ml Liquid 30 ml depends on the condition it is prescribed for. Young people taking it for conduct disorders, will usually only take it for around 6 weeks. Whereas, if it’s for bipolar disorder or schizophrenia, you will probably be asked to take it for a few years, otherwise, your condition can relapse. 

#4. Can I stop taking Buzon Oral 1mg/ml Liquid 30 ml?

Do not just stop taking the medicine, make sure to complete your treatment course even if you feel better. Stopping it suddenly may cause problems like difficulty sleeping, nausea, vomiting, sweating, and uncontrollable muscle movements. 

#5. Can I drink alcohol with Buzon Oral 1mg/ml Liquid 30 ml?

Avoid consuming alcohol when taking Buzon Oral 1mg/ml Liquid 30 ml to prevent drowsiness and risk of stomach problems.

#6. What if I take too much of Buzon Oral 1mg/ml Liquid 30 ml?

If you have taken too much of the prescribed Buzon Oral 1mg/ml Liquid 30 ml you may experience symptoms of overdose for example, fast, pounding, or irregular heartbeat, upset stomach, blurred vision, fainting, dizziness, and seizures. Contact your doctor immediately if you have any of these symptoms. 

#7. What if I forget to take Buzon Oral 1mg/ml Liquid 30 ml?

In case you miss a dose, take your next dose on time and do not try making up for the missed dose by doubling it up. If it helps to remind you, set an alarm so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

#8. Can I take Buzon Oral 1mg/ml Liquid 30 ml during pregnancy or breastfeeding?

If you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor before using Buzon Oral 1mg/ml Liquid 30 ml as it is contraindicated.

If you are breastfeeding, please consult your doctor before taking Buzon Oral 1mg/ml Liquid 30 ml as it is contraindicated.

#9. Can the use of Buzon Oral 1mg/ml Liquid 30 ml cause drowsiness?

It may cause drowsiness, dizziness, fatigue (tiredness), and visual disturbances. However, it is uncommon and is not reported by many people. If you experience any of these symptoms avoid driving or operating heavy machinery.

#10. Is Buzon Oral 1mg/ml Liquid 30 ml addictive?

It is not addictive but should only be taken as prescribed. 

#11. Is it safe to use Buzon Oral 1mg/ml Liquid 30 ml for a long time?

Buzon Oral 1mg/ml Liquid 30 ml has potential long-term side effects, which include dyskinesia (movement disorder), increased blood sugar levels, high triglycerides, and weight gain. 

#12. Will Buzon Oral 1mg/ml Liquid 30 ml affect my heart?

It can increase your risk of an irregular heartbeat if you have a history of heart diseases. Make sure to inform your doctor before using Buzon Oral 1mg/ml Liquid 30 ml

#13. Can I drive or ride a bike after taking Buzon Oral 1mg/ml Liquid 30 ml?

Make sure you know how your body reacts while using ‘product’ as it is known to make you feel dizzy. Do not drive or use any machinery until you feel normal again

#14. How should Buzon Oral 1mg/ml Liquid 30 ml be stored?

Store it at room temperature, away from excess heat and moisture. Do not freeze the liquid form of the medication. Make sure it is not consumed by pets, children, and other people. Dispose of the unused medicine.