Risp 4mg Tablet 6 ‘S

Description

Risp 4mg Tablet 6 ‘S belongs to a class of drugs called “atypical antipsychotics” (benzisoxazole derivative) used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder, irritability associated with autistic disorder).

Atypical antipsychotics (AAP) are also known as second generation antipsychotics (SGAs) and serotonin-dopamine antagonist (SDAs) are a group of drugs (in general also known as major tranquilizers and neuroleptics) are used to treat psychiatric conditions.

It is available on prescription, as tablets, dispersible tablets, liquid and long acting injection. Risp 4mg Tablet 6 ‘S works by altering the activity of chemical substances in the brain thereby reducing the symptoms of psychosis. Risp 4mg Tablet 6 ‘S helps in shortening the recovery time and prevents relapses. 

Common side effects of this medication are nausea, vomiting, diarrhoea, stomach ache, wind or loss of appetite, dizziness, headaches and mild rash.

Dosage of Risp 4mg Tablet 6 ‘S depends on age, severity of condition, patient’s response to medicine and their comorbidities. In children it is also based on their weight. 

Indications

It is used in the treatment of:

• Symptoms of schizophrenia (a mental illness characterised by disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and teenagers 13 years of age and older.
• Episodes of mania (frenzied, abnormally excited, or irritated mood) or mixed episodes (symptoms of mania and depression that happen together) in adults and in teenagers. 
• Bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods) in adults and children above 10 years of age. 
• Behavior problems such as aggression, self-injury, and sudden mood changes in teenagers and children between 5 to 16 years of age who have autism (a developmental disorder causing repetitive behavior, difficulty interacting with others and communication problems)

How does Risp 4mg Tablet 6 ‘S work?

It is an atypical antipsychotic that works by altering the activity of chemical substances in the brain thereby reducing the symptoms of psychosis. Risp 4mg Tablet 6 ‘S also helps in shortening the recovery time and prevents relapses. 

How to use Risp 4mg Tablet 6 ‘S?

• Risp 4mg Tablet 6 ‘S is available as tablets, dispersible tablets/orally disintegrating tablets (tablets that dissolve quickly in the mouth), liquid and long acting injection. 
• Risp 4mg Tablet 6 ‘S is usually prescribed to be taken once or twice a day with or without food at around the same time(s) every day. 
• Take Risp 4mg Tablet 6 ‘S as prescribed by your doctor. 
• Use the dropper provided to measure your dose for oral solution. It can be taken with water, orange juice, coffee, or low-fat milk. Do not take the solution with tea or cola.
• Avoid pushing the orally disintegrating tablet through the foil. Instead, peel back the foil packaging using dry hands. Place the tablet on your tongue and it will quickly dissolve and can be swallowed with or without liquid. 
• Do not chew or crush the tablet.
• To allow your body to adjust to the medication, your doctor will probably start you on a low dose of risperidone and then gradually increase it with time. 

Dosage

Schizophrenia:

Adults 

• Initial dose: 2 mg
• Titrations (increments): 1 to 2 mg
• Target dose: 4 to 8 mg
• Effective dose range: 4 to 16 mg

 Adolescents

• Initial dose: 0.5 mg
• Titration (increments):0.5 to 1 mg
• Target dose: 3 mg
• Effective dose range: 1 to 6 mg

Bipolar mania: 

Adults

• Initial dose: 2 to 3 mg
• Titration (increments):  1 mg
• Target dose:  1 to 6 mg
• Effective dose range: 1 to 6 mg

Children and adolescents

• Initial Dose: 0.5 mg
• Titration (increments): 0.5 to 1 mg
• Target dose:  1 to 2.5 mg
• Effective dose range: 1 to 6 mg

Irritability in autistic disorder:

• Initial dose:  
  • 0.25 mg can increase to 0.5 mg by Day 4: (body weight less than 20 kg) 
  • 0.5 mg Can increase to 1 mg by Day 4: (body weight greater than or equal to 20 kg)
• Titration (increments): After Day 4, at intervals of > 2 weeks: 
  • 0.25 mg (body weight less than 20 kg) 
  • 0.5 mg (body weight greater than or equal to 20 kg)
• Target dose: 
  • 0.5 mg: (body weight less than 20 kg) 
  • 1 mg: (body weight greater than or equal to 20 kg)
• Effective dose range: 0.5 to 3 mg

Doses are modified accordingly if a patient has renal or hepatic impairment.

Pregnancy use and lactation

If you are pregnant, think you may be pregnant or are planning to have a baby, please consult your doctor before using Risp 4mg Tablet 6 ‘S as it is contraindicated.

If you are breastfeeding, please consult your doctor before taking Risp 4mg Tablet 6 ‘S as it is contraindicated.

Contraindications

Please inform your doctor if you have a history of any before using Risp 4mg Tablet 6 ‘S:

• Allergic reaction to Risp 4mg Tablet 6 ‘S – indicated by skin rash, swelling around face area, wheezing, chest tightness and breathing difficulty

Precautions

Please tell your doctor about any of the following conditions while using Risp 4mg Tablet 6 ‘S:

• Elderly
• Renal impairment
• Hepatic impairment
• Cardiovascular Disease
• Epilepsy
• Parkinsonism
• Dementia
• Hyperprolactinaemia
• Diabetes
• Bradycardia
• Hypokalaemia 
• Hypomagnesaemia
• Family history of QT prolongation. 
• Driving/Operating Machinery.
• Monitor for signs of tardive dyskinesia, withdraw if these occur. 
• Monitor for hyperglycaemia and weight gain. 
• Risk factors for stroke 
• Monitor patients with a history of low wbc count or drug-induced leukopenia/neutropenia.
• Monitor endocrinological status, sedative effects and for the development of extrapyramidal symptoms and other movement disorders in children. Withdraw gradually.

Interaction with other medications

Certain medications could interact with Risp 4mg Tablet 6 ‘S, hence, in that case your doctor might alter your dosage and make sure to monitor blood sugar levels more closely.

Please inform your doctor about the use of the following before taking Risp 4mg Tablet 6 ‘S:

• Centrally acting drugs like levodopa 
• Dopamine agonists
• Drugs that prolong QT interval
• Alcohol
• Antihistamines 
• Benzodiazepines 
• Antihypertensives
• Paliperidone
• Psychostimulants
• Paroxetine, fluoxetine and other CYP2D6 inhibitors
• Itraconazole, ketoconazole, verapamil and other CYP3A4 and/or P-gp inhibitors and inducers
• Carbamazepine
• Rifampicin  
• Furosemide
• Anticholinergics

Adverse effects

Like most medicines, Risp 4mg Tablet 6 ‘S has some side effects which include:

Common:

• Nausea 
• Vomiting 
• Diarrhoea 
• Indigestion (stomach ache)
• Loss of appetite 
• Dizziness
• Headaches
• Mild rash

Serious:

• Hypersensitivity/allergic skin reactions; in this case discontinue 
• Orthostatic hypotension
• Reflex tachycardia
• Extrapyramidal symptoms
• Menstrual disturbance
• Sexual dysfunction
• Insomnia
• Anxiety
• Agitation
• Impaired concentration
• Weight Gain
• Rhinitis
• Blurred Vision
• Depression
• Somnolence 
• Ear Infection 
• Dyspnoea 
• Epistaxis
• Cough 
• Nasal Congestion 
• Pharyngolaryngeal Pain 
• Dry Mouth
• Toothache 
• Priapism
• Urinary Incontinence, Uti
• Tachycardia 
• Gynaecomastia
• Altered Lfts
• Hyperglycaemia
• Hyperprolactinaemia
• Anaemia
• Conjunctivitis
• Asthenia
• Fatigue
• Muscle Spasm
• Musculoskeletal Pain
• Pain In Extremities
• Pyrexia
• Oedema
• Chest Pain
• Flu-like Illness
• Rarely, Neuroleptic Malignant Syndrome
• Water Intoxication With Hyponatremia
• Seizures
• Tardive Dyskinesia
• Intraoperative Floppy Iris Syndrome

How to cope with some of the adverse effects

• Nausea (feeling sick) – Take Risp 4mg Tablet 6 ‘S with meals to avoid feeling sick.

• Vomiting/Diarrhoea – Keep yourself hydrated by having lots of fluids and if the problem persists, consult your doctor before taking any medication for vomiting and diarrhoea

• Loss of appetite – Continue having your meals at times that you would usually have them. If it helps, decrease the portion of your meals and have them more frequently. Snack on high protein food items like fruits and nuts. 

• Indigestion – Avoid food items that cause wind. Try having smaller and more frequent meals.

• Headache – Take a painkiller, rest and keep yourself hydrated at all times. Contact your doctor if your headaches last more than a week and/or become severe.

• Dizziness – Try and rest until you feel better and refrain from driving or using any tools or machinery

• Mild rash – Use a cream or ointment to moisturise, soothe and hydrate the affected area. If it doesn’t get better in a week contact your doctor.

Inform your doctor immediately if you experience any of the serious side effects.

Key facts about Risp 4mg Tablet 6 ‘S

• Risp 4mg Tablet 6 ‘S belongs to a class of drugs called “atypical antipsychotics” (benzisoxazole derivative) used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder, irritability associated with autistic disorder).
• Atypical antipsychotics (AAP) are also known as second generation antipsychotics (SGAs) and serotonin-dopamine antagonist (SDAs) are a group of drugs (in general also known as major tranquilizers and neuroleptics) are used to treat psychiatric conditions.
• It is prescribed to adults and children.
• Risp 4mg Tablet 6 ‘S should be taken with food or milk to prevent upset stomach
• It is available as tablets, dispersible tablets/orally disintegrating tablets (tablets that dissolve quickly in the mouth), liquid and long acting injection. 
• It may take upto 4-6 weeks for the medicine to start showing significant effects. 
• Common side effects of this medication are nausea, vomiting, diarrhoea, stomach ache, wind or loss of appetite, dizziness, headaches and mild rash.
• It may cause excessive drowsiness and increase your risk of stomach problems if you consume alcohol while taking Risp 4mg Tablet 6 ‘S.
• It may cause an increase in weight, blood sugar, cholesterol, and fat. Eat healthy, exercise, and monitor your levels regularly.
• Matter of concern arises if you get a rash, itchy skin, swelling on the face and difficulty breathing, in which case you need to inform your doctor immediately. 

FAQs

1. WHAT EXACTLY DOES Risp 4mg Tablet 6 ‘S DO?

It is an atypical antipsychotic that works by altering the activity of chemical substances in the brain thereby reducing the symptoms of psychosis. Risp 4mg Tablet 6 ‘S also helps in shortening the recovery time and prevents relapses. 

2. HOW LONG DOES IT TAKE FOR Risp 4mg Tablet 6 ‘S TO START WORKING?

It may take upto 4-6 weeks for the medicine to start showing significant effects. Keep taking Risp 4mg Tablet 6 ‘S as prescribed. 

3. HOW LONG WILL I HAVE TO TAKE Risp 4mg Tablet 6 ‘S FOR?

The duration for using Risp 4mg Tablet 6 ‘S depends on the condition it is prescribed for. Young people taking it for conduct disorders, will usually only take it for around 6 weeks. WHereas, if it’s for bipolar disorder or schizophrenia, you will probably be asked to take it for a few years, otherwise your condition can relapse.

4. CAN I STOP TAKING Risp 4mg Tablet 6 ‘S?

Do not just stop taking the medicine, make sure to complete your treatment course even if you feel better. Stopping it suddenly may cause problems like difficulty sleeping, nausea, vomiting, sweating and uncontrollable muscle movements. 

5. CAN I DRINK ALCOHOL WITH Risp 4mg Tablet 6 ‘S?

Avoid consuming alcohol when taking Risp 4mg Tablet 6 ‘S to prevent drowsiness and risk of stomach problems.

6. WHAT IF I TAKE TOO MUCH OF Risp 4mg Tablet 6 ‘S?

If you have taken too much of the prescribed Risp 4mg Tablet 6 ‘S you may experience symptoms of overdose for example, fast, pounding, or irregular heartbeat, upset stomach, blurred vision, fainting, dizziness and seizures. Contact your doctor immediately if you have any of these symptoms. 

7. WHAT IF I FORGET TO TAKE Risp 4mg Tablet 6 ‘S?

Incase you miss a dose, take your next dose on time and do not try making up for the missed dose by doubling it up. If it helps to remind you, set an alarm so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

8. CAN I TAKE Risp 4mg Tablet 6 ‘S DURING PREGNANCY OR BREASTFEEDING?

If you are pregnant, think you may be pregnant or are planning to have a baby, please consult your doctor before using Risp 4mg Tablet 6 ‘S as it is contraindicated.

If you are breastfeeding, please consult your doctor before taking Risp 4mg Tablet 6 ‘S as it is contraindicated.

9. CAN THE USE OF Risp 4mg Tablet 6 ‘S CAUSE DROWSINESS?

It may cause drowsiness, dizziness, fatigue (tiredness) and visual disturbances. However, it is uncommon and is not reported by many people. If you experience any of these symptoms avoid driving or operating heavy machinery.

10. IS Risp 4mg Tablet 6 ‘S ADDICTIVE?

It is not addictive but should only be taken as prescribed. 

11. IS IT SAFE TO USE Risp 4mg Tablet 6 ‘S FOR A LONG TIME?

Risp 4mg Tablet 6 ‘S has potential long term side effects, which include dyskinesia (movement disorder), increased blood sugar levels, high triglycerides and weight gain. 

12. WILL Risp 4mg Tablet 6 ‘S AFFECT MY HEART?

It can increase your risk of irregular heartbeat if you have a history of heart diseases. Make sure to inform your doctor before use Risp 4mg Tablet 6 ‘S

13. CAN I DRIVE OR RIDE A BIKE AFTER TAKING Risp 4mg Tablet 6 ‘S?

Make sure you know how your body reacts while using Risp 4mg Tablet 6 ‘S as it is known to make you feel dizzy. Do not drive or use any machinery until you feel normal again

14. HOW SHOULD Risp 4mg Tablet 6 ‘S BE STORED?

Store it at room temperature, away from excess heat and moisture. Do not freeze the liquid form of the medication. Make sure it is not consumed by pets, children and other people. Dispose of the unused medicine.