Lamisil 125mg Tablet 10 ‘S

Description

About

Lamisil 125mg Tablet 10 ‘S belongs to a group of chemicals known as azoles which aid in treating fungal infections such as nail infection, athlete’s foot, ringworm infections, groin infection, and similar fungal conditions. Lamisil 125mg Tablet 10 ‘S is chemically composed of Terbinafine, effective against a number of yeast infections. 

Lamisil 125mg Tablet 10 ‘S is classified as an Azoles antifungal which acts by blocking an important enzyme involved in the synthesis of key components for the fungal cell wall, indirectly targeting it and causing fungal cell death due to altered permeability of the fungal cell walls.

Lamisil 125mg Tablet 10 ‘S is available in the form of oral tablets, meant to be taken by mouth in doses prescribed by the doctor. Lamisil 125mg Tablet 10 ‘S is commonly prescribed as one tablet daily and the treatment may continue for 4 – 12 weeks depending on the infection. It may take up to weeks before clinical improvements in fungal infection are seen. Not considered safe in pregnancy, Lamisil 125mg Tablet 10 ‘S is safely prescribed to adults and children above 4 years of age. Some common side effects of Lamisil 125mg Tablet 10 ‘S include nausea, vomiting, rash, metallic taste, etc. 

Indications

Lamisil 125mg Tablet 10 ‘S can be used to treat:

• Nail infection (onychomycosis)
• Skin infection
• Athlete’s foot
• Fungal infection in the groin area
• Ringworm infections

How Does Lamisil 125mg Tablet 10 ‘S Work

Lamisil 125mg Tablet 10 ‘S shows its antifungal effects by blocking an important enzyme, Squalene epoxidase involved in the synthesis of key components for the fungal cell wall, indirectly targeting it and causing fungal cell death due to accumulation of toxic substances within the cell and altered permeability of the fungal cell walls.

How To Use Lamisil 125mg Tablet 10 ‘S

Lamisil 125mg Tablet 10 ‘S is available as oral tablets to be taken orally with or without food. Do not take more than recommended. The dose is usually given as a single tablet (once daily) and the treatment is commonly continued for 4-12 weeks or as per the patient’s condition. Make sure to complete your treatment till full prescription to avoid recurrence. Lamisil 125mg Tablet 10 ‘S is not advised to be given to children under the age of 4 years. For Elderly patients, a tablet per day is prescribed, kidney and liver functions must be considered before prescribing this medicine. 

Available Potency and forms of Lamisil 125mg Tablet 10 ‘S 

• Tablet – 125 mg
• Tablet – 250 mg

Adult dose

Onychomycosis – Tinea Unguium

Fingernails: 250 mg, Once a day  orally for 6 weeks

Toenails:  250 mg, Once a day  orally for 12 weeks

Athlete’s foot  – Tinea Pedis

250 mg, Once a day  orally for 2 to 6 weeks depending on improvement in the condition

Jock itch  – Tinea Cruris

250 mg, Once a day  orally for 2 to 4 weeks

Ringworm of scalp – Tinea Capitis

250 mg, Once a day  orally for 6 weeks

Pediatric Dose

Oral granules (125 mg) are more suited for children because of compliance and easy intake. However, whenever tablets are indicated in children 4 years and above, the following dose as per the child’s body weight can be used to calculate the exact dose.

Daily dose : recommended once a day for  – 5 mg/kg

< 25 mg –  62.5 mg / day

25 – 35 kg – 125 mg / day

> 40 kg – 250 mg / day

Elderly dose

In general, the dose in these patients matches those of the adults. But dose adjustment should be considered in case of kidney and liver impairment or reduced function to avoid harmful effects. In case of severe liver dysfunction, Lamisil 125mg Tablet 10 ‘S should be avoided.

Special Case

*Renal Impairment: Caution must be exercised, low doses advised

Hepatic Impairment: Drug is best avoided

Pregnancy Use And Lactation

Lamisil 125mg Tablet 10 ‘S contains Terbinafine in its formulation which is classified as pregnancy category B (No known risk to the fetus in studies conducted on animals and lack of data in pregnant humans). However, this drug should not be prescribed to expecting and lactating mothers due to unknown effects, and should only be prescribed if absolutely necessary after consulting a doctor. 

Contraindications

Please tell your doctor if you have a history of any of the following before using Lamisil 125mg Tablet 10 ‘S:

• Allergy to Lamisil 125mg Tablet 10 ‘S or similar drugs
• Pregnancy
• Breastfeeding 
• History of depression or other mental health disorders
• Patients less than 4 years old
• Hepatic failure / or reduced liver function
• Autoimmune disorders such as SLE, Psoriasis
• Neutropenia 

Precautions

Please tell your doctor about any of the following conditions before using Lamisil 125mg Tablet 10 ‘S

• Lamisil 125mg Tablet 10 ‘S must be used with caution if you have a history of drug-related allergies
• In case of decreased liver function, Lamisil 125mg Tablet 10 ‘S must not be used due to a high risk of liver complications
• Lamisil 125mg Tablet 10 ‘S should be used in low doses in compromised kidneys or  disease, as adjusted by your doctor
• Lamisil 125mg Tablet 10 ‘S may put you at risk of more infections because it can cause neutropenia (decreased neutrophils). It is more common in women and a reversible condition
• Photosensitivity has also been reported while taking Lamisil 125mg Tablet 10 ‘S, a good quality sunblock and full coverage with clothing is recommended when going outside
• Autoimmune disorders like SLE or Lupus tend to worsen with Lamisil 125mg Tablet 10 ‘S, avoid this medicine in this case
• Alcohol intake should be restricted
• Lamisil 125mg Tablet 10 ‘S is known to potentiate the effects of Caffeine, these caffeinated products (including tea, coffee, soft/ or energy drinks, chocolate, etc) should therefore be avoided or limited 
• Lamisil 125mg Tablet 10 ‘S is not considered safe for pregnant and lactating mothers
• Lamisil 125mg Tablet 10 ‘S is associated with a change in taste and smell, if you notice this symptom consult your physician 
• It is beneficial to get blood tests done a few weeks after starting Lamisil 125mg Tablet 10 ‘S to check Liver function test and blood cell count

Interactions With Other Medications

Please tell your doctor about the use of the following before using Lamisil 125mg Tablet 10 ‘S, few of the interacting drugs are:

• Cimetidine 
• Rifampin 
• Certain Antidepressants belonging to SSRIs, TCAs, MAO Inhibitors
• Amiodarone 
• Tamoxifen 
• Beta-blockers 
• Warfarin 
• Triazolam
• Toulbatine 
• Fluconazole
• Ciclosporin 
• Oral Contraceptives

Adverse Effects

Common Side Effects

• Nausea, vomiting, diarrhea
• Drowsiness
• Fatigue 
• Abdominal pain
• Lightheadedness 
• Pruritus 
• Dysgeusia (change in taste) 

Less Common Side Effects

• Hypersensitivity Reaction 
• Liver disease (appetite loss, pale skin, discolored stool/urine, weight loss)
• Anosmia (loss of smell)
• Photosensitivity 
• Skin rash 
• Worsening or newly developed Lupus 
• Visual disturbances 
• Depression 
• Mood changes 
• Abnormal Liver function tests
• Neutropenia 

How To Deal With Some Side Effects

• Feeling or being sick (nausea or vomiting) or diarrhea -Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water.
• Feeling drowsy – If the medication makes you feel drowsy or sleepy, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Headaches– In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
• Feeling dizzy (lightheaded) or weak – If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from sitting or lying down to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Flatulence– This can be eased by consuming smaller, more frequent meals that don’t trigger your flatulence.Getting a minimum of 30 minutes of daily exercise has shown great results in combating flatulence. 
• Heartburn – can be dealt with by chewing on mint-flavored gum that’ll help neutralize the acid in the body. Standing up straighter, adding ginger to the daily diet, elevating the patient’s upper body, and having licorice supplements has shown to provide relief.
• Skin Rash– can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. Antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Change in taste– this tends to go away as soon as the patient stops taking the medicine but while treatment; saltwater with baking soda (half a teaspoon of salt and baking soda in water) rinses and chewing on sugar-free gum can help dissipate the change in taste.
• Blurred vision – This side effect tends to go away on its own if a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime.If blurred vision persists, please contact your doctor.
• Photosensitivity – Minimize exposure to the sun most importantly. Patients are asked to wear sun-protective clothes when going outside including gloves and hats, to apply generous amounts of broad-spectrum sunblock along with wearing sunglasses. Patients are advised to do all necessary work after sunset so as to reduce or eliminate sun exposure while undergoing treatment with Lamisil 125mg Tablet 10 ‘S.

FAQS

#1.What If I Take Too Much Of Lamisil 125mg Tablet 10 ‘S?

In case of too much consumption by accident, kindly contact your doctor or nearby hospital straight away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

#2. How Is Lamisil 125mg Tablet 10 ‘S Supposed To Be Taken?

{{product} is to be ingested orally once daily or as per doctor’s prescription, usually up to 6-12 weeks depending on the condition being treated. Lamisil 125mg Tablet 10 ‘S is to be taken either with or without food, with water to ease the tablet’s passage to the patient’s throat.

#3. How Does Lamisil 125mg Tablet 10 ‘S Work?

 Lamisil 125mg Tablet 10 ‘S is an antifungal medication used to treat fungi infecting the human body. It acts by blocking an important enzyme involved in the synthesis of key components for the fungal cell wall, indirectly targeting it and causing fungal cell death due to altered permeability of the fungal cell walls.

#4. Can I Take Lamisil 125mg Tablet 10 ‘S During My Pregnancy?

No, although Lamisil 125mg Tablet 10 ‘S is classified as a category B by FDA meaning there are no known risks to the fetus in studies conducted on animals but due to data in pregnant humans being sparse, it is best avoided unless absolutely necessary and advised by our doctor. 

#5. Can I Take Lamisil 125mg Tablet 10 ‘S During Breastfeeding?

No,  Lamisil 125mg Tablet 10 ‘S is secreted into breast milk and due to unknown side effects on the lactating infant, it should be avoided and only be prescribed if absolutely necessary after consulting a doctor. 

#6. Are There Any Food Products Which Should Be Avoided With Lamisil 125mg Tablet 10 ‘S?

Caffeine is known to interact with Lamisil 125mg Tablet 10 ‘S, with its effects increased. Therefore, caffeinated products like energy or soft drinks, chocolate, tea, coffee should be avoided or taken in a limited amount. Also, alcohol consumption must also be limited. 

#7. What If I Forget To Take Lamisil 125mg Tablet 10 ‘S?

It is advised that the drug is taken at the same time each day, an alarm, pill organizers, or a mobile phone application can be used to remind patients to take Lamisil 125mg Tablet 10 ‘S at the proper time. If the patient misses a dose of Lamisil 125mg Tablet 10 ‘S, they should take it immediately but if the time for the next dose of the drug is near then patients should skip the missed dose and take the tablets as per schedule, doubling of doses has proven to cause severe side effects.

#8. Can Lamisil 125mg Tablet 10 ‘S Interfere With Fertility?

Lamisil 125mg Tablet 10 ‘S may cause hormonal irregularities, irregular menstrual cycles according to some studies but there isn’t sufficient evidence to suggest that Lamisil 125mg Tablet 10 ‘S interferes with female fertility otherwise.

#9. Can I Drive After Taking Lamisil 125mg Tablet 10 ‘S?

Yes, you can drive or ride a bike but if you notice that Lamisil 125mg Tablet 10 ‘S is making you dizzy, kindly avoid driving or operating any heavy machinery until this side effect subsides.

#10. Are There Any Particular Lifestyle Changes I Need To Make While Using Lamisil 125mg Tablet 10 ‘S?

Personal hygiene is of utmost importance if you are suffering from a fungal infection. Following changes may help you prevent the spread of your disease or have reinfection:

• Wash your hands thoroughly after touching the infection site
• Do not share clothes, towels, or bed sheets and wash with water. These items must be changed frequently 
• Avoid wearing full-coverage shoes for longer periods 
• Open shoes like sandals should be worn or air dry shoes properly before wearing them again
• Dri-fit socks and clothes should be worn to avoid staying in wet clothing
• Keep your skin clean, dry and cool
• Avoid using public baths and swimming pools

#11. Will I Have To Take Any Tests While Under Treatment With Lamisil 125mg Tablet 10 ‘S?

Your doctor may like to check your Liver Function by testing LFTS before prescribing you Lamisil 125mg Tablet 10 ‘S. It is beneficial to get blood tests done a few weeks after starting Lamisil 125mg Tablet 10 ‘S to check Liver function test and blood cell count, and PT, INR if you are on anticoagulants. 

#12. How To Store Lamisil 125mg Tablet 10 ‘S?

Lamisil 125mg Tablet 10 ‘S is to be kept away from the reach of children, in a cool dry place away from direct sunlight and moisture as that tends to damage certain drugs.