Rotrif 40/240mg Tablet 10 ‘S

Description

About

Rotrif 40/240mg Tablet 10 ‘S is prescribed to patients suffering from an active malarial infection.Rotrif 40/240mg Tablet 10 ‘S is a combination of two drugs,both of which are from the same chemical group known as antimalarial drugs.Malaria is transmitted through mosquitoes (plasmodium falciparum) and is prevalent in many countries.The virus once transmitted can infect human blood cells or the liver.Rotrif 40/240mg Tablet 10 ‘S is prescribed to eliminate viruses from infected blood cells.Rotrif 40/240mg Tablet 10 ‘S is not used for prevention of malaria.

Two tablets daily are usually (commonly) prescribed.Rotrif 40/240mg Tablet 10 ‘S is to be taken regularly with food,preferably at the same time each day to help the patient remember their daily dose.The patient ought to discuss with their physician before ceasing intake of the medicine even if the patient is no longer suffering from common symptoms of malaria,as ceasing the intake of the medicine has reported in cases of reinfection.

Rotrif 40/240mg Tablet 10 ‘S might show mild side effects such as headaches,dizziness and stomach problems which resolve on their own in a few days’ time.Rotrif 40/240mg Tablet 10 ‘S is not safe to be prescribed to pregnant or lactating mothers.While undergoing treatment with Rotrif 40/240mg Tablet 10 ‘S,the physician may ask the patient to get certain lab work done periodically to monitor the effects of the drug on the patient’s body and monitor the patient’s blood pressure,ECG readings and potassium levels regularly.Accordingly the physician may change the dosage of the drug prescribed.

Indications

Rotrif 40/240mg Tablet 10 ‘S can be used to treat:

• Malaria 

How Does Rotrif 40/240mg Tablet 10 ‘S Work

Rotrif 40/240mg Tablet 10 ‘S works by destroying the parasite and preventing its reproduction in the human blood cells.

How To Use Rotrif 40/240mg Tablet 10 ‘S

Rotrif 40/240mg Tablet 10 ‘S is meant to be ingested orally (by mouth) with food or milk for a 3 day period.Rotrif 40/240mg Tablet 10 ‘S can be ingested whole or crushed and sprinkled on food or mixed in with water or infant formula.

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next day, do not double the dose and take your medication as per schedule as that will lead to serious adverse effects. If this happens very often, try setting an alarm as a reminder.

Dosage

Adult Dosage

2-4 tablets a day are commonly prescribed to be spaced out evenly throughout the day for a 3 day period.

Child Dosage

Rotrif 40/240mg Tablet 10 ‘S is safe to be prescribed to patients aged 2 months and older.The dosage for each individual is based on their weight and age.Commonly a tablet a day is prescribed to children weighing between 5 to 15kgs for a period of 3 days.The dosage may be increased with the weight and age of child.

Elderly Dosage 

Sufficient research has not been done on the effects of Rotrif 40/240mg Tablet 10 ‘S on elderly patients and thus Rotrif 40/240mg Tablet 10 ‘S is not currently prescribed to patients aged 65 years and above.

Pregnancy Use And Lactation

This drug is not to be taken or prescribed to expecting and lactating mothers as it may have fatal consequences for the unborn child.If you are taking the drug and become pregnant,inform your doctor immediately.Small amounts of this drug can be transferred to the child through breast milk and therefore Rotrif 40/240mg Tablet 10 ‘S isn’t recommended to lactating mothers.If you are planning to conceive and are taking Rotrif 40/240mg Tablet 10 ‘S as treatment, then refer to the doctor.The physician is likely to change your medicine and dosage.

Contraindications

Please tell your doctor if you have a history of any of the following before using Rotrif 40/240mg Tablet 10 ‘S:

• Allergy to Rotrif 40/240mg Tablet 10 ‘S or any other medicine or food substance 
• Arrhythmias (irregular heart rhythm)
• Clinical relevant bradycardia (slow heart rate)
• Congestive heart failure accompanied by reduced ventricular ejection fraction (measurement of blood pumped out of heart with each contraction)
• Family history of sudden death or of congenital QT interval prolongation (electrical disturbance in heart since birth)
• Severe malaria
• Other plasmodium infections.

Precautions

Please tell your doctor about any of the following conditions before using Rotrif 40/240mg Tablet 10 ‘S:

• Electrolyte disturbances
• Concomitant use with other drugs known to cause QT-interval prolongation (electrical disturbance in heart) 
• Severe cardiac (heart) impairment
• Renal (kidney) impairment
• Hepatic (liver) impairment

Interactions With Other Medications

Please tell your doctor about the use of the following before using Rotrif 40/240mg Tablet 10 ‘S:

• Inhibitors of CYP3A4
• Substrates of CYP2D6
• Grapefruit juice
• Class Ia and III antiarrhythmics
• Drugs prolonging QT interval
• Fluoroquinolones
• Azole antifungals
• Cisapride
• Other antimalarials
• Hormonal contraceptives
• Macrolides
• Antipsychotics
• Antidepressants.

Adverse Effects

Common Adverse Effects

Like most medicines,Rotrif 40/240mg Tablet 10 ‘S has certain side effects which include:

• Headaches
• Dizziness
• Weakness 
• Muscle pain 
• Loss of appetite 
• Stomach problems (vomiting)

These effects tend to be mild and resolve in a few days of taking Rotrif 40/240mg Tablet 10 ‘S.

Rare Adverse Effects

If any of the following adverse effects are seen or felt,the patient is advised to immediately contact their doctor

• Arrhythmias
• Rash
• Fainting 
• Cough 
• Swelling of hands,feet and ankles 

How To Cope With Some Of The Adverse Effects

• Feeling dizzy (lightheaded) or weak –If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Muscular Aches And Pains- A hot or cold compress can be placed at the area of discomfort to bring relief;an over the counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease aswell. Avoid high intensity exercise while suffering from muscular pain.
• Headaches- In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe.
• Dry Cough – Can be eased by adding honey to warm drinks and having oral lozenges,to provide soothing relief to an irritated throat.Ginger tea has been known to decrease inflammation of an irritated throat thus,providing relief.

Key Facts About Rotrif 40/240mg Tablet 10 ‘S

• Rotrif 40/240mg Tablet 10 ‘S is used to treat malaria 
• Rotrif 40/240mg Tablet 10 ‘S may cause weakness,headaches and fatigue 
• Rotrif 40/240mg Tablet 10 ‘S is not prescribed to patients suffering from severe heart impairment 
• Rotrif 40/240mg Tablet 10 ‘S is said to interact negatively with certain hormonal contraceptives
• Rotrif 40/240mg Tablet 10 ‘S is not safe to be prescribed to pregnant and lactating women
• Rotrif 40/240mg Tablet 10 ‘S may be prescribed to children aged two months and above

FAQs

#1.IS IT SAFE TO HAVE Rotrif 40/240mg Tablet 10 ‘S ALONG WITH ORAL CONTRACEPTIVES?

Not all oral contraceptives are safe to be taken while undergoing treatment with Rotrif 40/240mg Tablet 10 ‘S as certain oral contraceptives (birth control pills) may negatively interact with Rotrif 40/240mg Tablet 10 ‘S.Please consult your doctor before taking any medication while ingesting Rotrif 40/240mg Tablet 10 ‘S.

#2.HOW TO STORE Rotrif 40/240mg Tablet 10 ‘S?

Rotrif 40/240mg Tablet 10 ‘S is to be kept away from the reach of children,in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.

#3.WHAT IF I TAKE TOO MUCH OF Rotrif 40/240mg Tablet 10 ‘S?

 An extra dose or two of Rotrif 40/240mg Tablet 10 ‘S is not known to cause any harm but an excess ingestion of Rotrif 40/240mg Tablet 10 ‘S is a cause for concern and should be avoided and immediately reported to the doctor as it may lead to serious side effects such as fainting,breathlessness and irregular heartbeats.

#4.WHAT IF I MISS A DOSE OF Rotrif 40/240mg Tablet 10 ‘S?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next dosage time or next day, do not double the dose and take your medication as per schedule.

#5.WILL Rotrif 40/240mg Tablet 10 ‘S AFFECT MY SEXUAL ACTIVITY?

No,there isn’t sufficient evidence to suggest that patients experience a decrease in libido.

#6.CAN I TAKE Rotrif 40/240mg Tablet 10 ‘S DURING MY PREGNANCY?

No,Rotrif 40/240mg Tablet 10 ‘S is deemed unsafe to be ingested during pregnancy.

#7.WHAT ARE COMMON SIDE EFFECTS CAUSED BY Rotrif 40/240mg Tablet 10 ‘S?

• Headaches
• Dizziness
• Weakness 
• Muscle pain 
• Loss of appetite 
• Stomach problems (vomiting)

#8.WHAT LAB TESTS WILL BE PRESCRIBED WHILE TREATMENT WITH Rotrif 40/240mg Tablet 10 ‘S AND HOW OFTEN?

Kidney and liver function tests along with blood tests to keep check on serum potassium levels are advised to be done periodically along with an occasional ECG test to monitor the OT intervals of a beating heart.

#9.CAN Rotrif 40/240mg Tablet 10 ‘S CAUSE DIZZINESS? IF SO, HOW SHOULD I MANAGE IT?

Yes. It can cause dizziness as one of the most common side effects. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during the course of your treatment, as it may worsen the dizziness.

#10.DOES Rotrif 40/240mg Tablet 10 ‘S CAUSE ADDICTION?

No.This drug has shown no evidence to prove addiction of any kind in any patient.

#11.WHAT IF I FORGET TO TAKE THE Rotrif 40/240mg Tablet 10 ‘S?

It is advised that the drug is taken at the same time each day,an alarm can be placed to remind patients to take Rotrif 40/240mg Tablet 10 ‘S at the proper time and at least an hour before having any meal.If patient misses a dose of Rotrif 40/240mg Tablet 10 ‘S,they should take it immediately but if the time for the next dose of the drug is near then its beneficial for patients to skip the missed dose and take the tablets as per schedule,doubling of doses has proven to cause severe side effects.

#12.IS Rotrif 40/240mg Tablet 10 ‘S SAFE TO GIVE TO ELDERLY PATIENTS?

Sufficient research has not been done on the effects of Rotrif 40/240mg Tablet 10 ‘S on elderly patients and thus Rotrif 40/240mg Tablet 10 ‘S is not currently prescribed to patients aged 65 years and above.