Mabil 500mcg/1ml Injection 1’S

Description

  • Mabil 500mcg/1ml Injection 1’S is a supplementary drug used to treat Vitamin B12 deficiency in conditions such as pernicious anemia, diabetic or alcoholic neuropathy, multiple sclerosis
  • Mabil 500mcg/1ml Injection 1’S is injected intramuscularly or intravenously 1-3 times per week depending on your condition, usually in the morning.
  • Consult your physician regarding dosage

Description

About

Vitamin B12 is vital for the body to keep working efficiently and effectively. It plays an important role in the production of the body’s red blood cells and neurological components of our brain. Mabil 500mcg/1ml Injection 1’S is a supplementary drug used to treat Vitamin B12 deficiency in conditions such as pernicious anemia, diabetic or alcoholic neuropathy, multiple sclerosis, and other conditions. Mabil 500mcg/1ml Injection 1’S is chemically composed of Mecobalamin which is a Vitamin B12 analog, crucial to the synthesis of healthy and normal red blood cells.

Mabil 500mcg/1ml Injection 1’S is available in injection form to be given intravenously or intramuscularly 1-3 times per week depending on your bodily requirements, usually in the morning. Consult your physician regarding dosage. Injections are particularly useful for those suffering from gastric or absorption problems. Common side effects such as headaches and stomach problems tend to resolve on their own in a few days. Patients are advised to refrain from consuming alcohol as it disrupts the absorption of the drug by the body.

Indications

Mabil 500mcg/1ml Injection 1’S can be used to treat:

  • Peripheral neuropathies 
  • Megaloblastic anemia
  • Pernicious anemia
  • Alcoholic neuropathy 
  • Diabetic neuropathy
  • Multiple sclerosis 
  • Malabsorption disorder
  • Gastrectomy (Surgical removal part of your intestine)
  • Gastric bypass producing mineral deficiency
  • A strict vegan diet which causes mineral deficiency 

How Does Mabil 500mcg/1ml Injection 1’S Work

Vitamin B12 is an essential mineral that helps in the production of the myelin sheath (the protective layer that wraps around the neurons) which helps in the conduction of nerve impulses. Methylcobalamin aids in the restoring and rejuvenation of the damaged neurons. When there is B12 deficiency there is also irreversible nerve damage, leading to neurological deficit. Moreover, it is involved in the synthesis of red blood cells (RBCs), deficiency of folate or vitamin B12 inhibits this production, and impairs DNA synthesis, resulting in anemia from ineffective or insufficient red cell production. 

How To Use Mabil 500mcg/1ml Injection 1’S

Mabil 500mcg/1ml Injection 1’S is available as a solution in ampoule form injected intravenously, as an infusion, or intramuscularly 1-3 times per week usually in the morning. depending on your condition, as advised by the doctor. Mabil 500mcg/1ml Injection 1’S is administered by a health care professional in a hospital setup. Alternatively, a healthcare provider can also inject it intramuscularly at home where indicated. The slow IV infusion can also be given which causes relatively less discomfort. Consult your physician regarding dosage since it varies from person to person. Patients are advised to inform their doctor of their daily alcohol intake as excessive amounts of alcohol in the body reduce the absorption rate of Mabil 500mcg/1ml Injection 1’S by the body.

Dosage

Adult Dose

For Peripheral neuropathy, Megaloblastic anemia, Pernicious anemia, and a few other ailments, an ampoule is commonly administered three times a week or as a maintenance dose on a weekly/ monthly basis.  Dosage can be altered on the advice of a doctor after a few weeks depending on the patient’s response to treatment and the patient’s vitamin B12 levels. Your doctor will decide about the exact amount you need after checking your vitamin levels, nutritional requirements you meet on daily basis and the number of days in a week Mabil 500mcg/1ml Injection 1’S must be administered. 

Child Dose 

Mabil 500mcg/1ml Injection 1’S can be safely administered to infants and children by a health professional in the dosage prescribed by the doctor. 

Following are the doses required as nutritional booster, according to age:

  • 6 months-1 year: 0.4 – 0.5 mcg
  • 1-3 years: 0.9 mcg
  • 5 – 8 years: 1.2 mcg
  • 9 – 12 years: 1.8 mcg
  • > 14 years: 2.4 mcg

Elderly Dose 

The dose is set by your doctor. Malabsorption conditions and nutritional deficiencies are common in the elderly population (65 years and above). Caution is advised with this age group while administering Mabil 500mcg/1ml Injection 1’S

Pregnancy Use and Lactation

There isn’t sufficient evidence to suggest that Mabil 500mcg/1ml Injection 1’S isn’t safe to be administered to pregnant or lactating women; regardless Mabil 500mcg/1ml Injection 1’S is to be taken after consulting a doctor. Dosage is altered for pregnant and lactating women to meet their needs. Before using Mabil 500mcg/1ml Injection 1’S discuss the dosage and safety with your physician.

Contraindications

Please tell your doctor if you have a history of any of the following before using Mabil 500mcg/1ml Injection 1’S:

  • Allergic to Mabil 500mcg/1ml Injection 1’S or any of its constituents

Precautions

Please tell your doctor about any of the following conditions before using Mabil 500mcg/1ml Injection 1’S

  •  Low serum potassium levels
  • History of serious allergic reactions to similar drugs
  • Optic neuropathy
  • Vitamin C supplements if taken simultaneously can decrease the amount of vitamin B12 absorption by your body. Avoid taking large doses of vitamin C within one hour before or after taking this product.
  • Avoid heavy alcohol consumption

Interactions With Other Medications

Please tell your doctor about the use of the following before using Mabil 500mcg/1ml Injection 1’S:

  • Chloramphenicol (antibiotic)
  • Colchicine (used for the treatment of gout)
  • Antidiabetic medicine (metformin)
  • Cimetidine (treatment for acid reflux and heartburn)
  • Omeprazole and other proton pump inhibitors (treatment for acid reflux and heartburn)
  • Alcohol
  • Lansoprazole
  • Potassium chloride
  • Pyrimethamine

Adverse effects

Mabil 500mcg/1ml Injection 1’S is unlikely to cause any serious side effects when used properly, but some side effects may include:

Common Side effects

  • Headache
  • Nausea and vomiting
  • Abdominal pain
  • Diarrhea 

Rare side effects

  • Anaphylactic reaction
  • Headache
  • Difficulty in breathing
  • Discolored stool
  • Change in taste
  • Hypervitaminosis (upon overdosage)

How To Cope with Some Of The Adverse Effects

  • Headaches – In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
  • Nausea or vomiting or diarrhea – Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. If you have diarrhea, replenish with plenty of water or other fluids. 
  • Feeling dizzy (lightheaded) or weak – If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Muscular Aches and Pains – A hot or cold compress can be placed at the area of discomfort to bring relief; an over-the-counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.
  • Constipation – Can be combated by adding more fibers to the patient’s diet, asking the patient to drink plenty of fluids, and increasing their physical activity to trigger contractions in the intestines.
  • Change in taste – This tends to go away as soon as the patient stops taking the medicine but while treatment; saltwater with baking soda (half a teaspoon of salt and baking soda in water) rinses and chewing on sugar-free gum can help dissipate the change in taste.
  • Blurred vision – This side effect tends to go away on its own in a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.
  • Soreness at the site of injection – A cold compress can be used for 5 minutes to ease out the soreness.

FAQS

#1. How To Store Mabil 500mcg/1ml Injection 1’S?

Mabil 500mcg/1ml Injection 1’S is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity as that tends to alter certain drugs.

#2. Can Mabil 500mcg/1ml Injection 1’S Cause Dizziness? If So, How Should I Manage It?

Yes. It can cause dizziness as one of the most common side effects. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during your treatment, as it may worsen the dizziness.

#3. Can I Drive After Taking This Medication?

This medication can make you dizzy hence if that happens kindly avoid driving or operating any heavy machinery.

#4. What If I Forget to Take Mabil 500mcg/1ml Injection 1’S?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next day, do not double the dose and take your medication as per schedule as that will lead to serious adverse effects. If this happens very often, try setting an alarm as a reminder.

#5. How Is Mabil 500mcg/1ml Injection 1’S Supposed to Be Taken?

The medicine can be administered intravenously and intramuscularly by a physician or nurse.

#6. Is It Safe to Take Mabil 500mcg/1ml Injection 1’S With Birth Control Pills?

Yes, it is safe as there is no evidence of Mabil 500mcg/1ml Injection 1’S interfering with any prescribed birth control drugs.

#7. Can I Have Alcohol While Taking Mabil 500mcg/1ml Injection 1’S?

Alcohol intake is discouraged in patients taking Mabil 500mcg/1ml Injection 1’S as excessive amounts of alcohol decrease the amount of Mabil 500mcg/1ml Injection 1’S absorbed by the body.

#8. What Foods Are A Good Source Of Vitamin B12?

  • Beef
  • Chicken
  • Fish
  • Eggs
  • Yogurt
  • Cheese
  • Milk.

# 9. How Should I Know That I Have Vitamin B12 Deficiency?

There are certain signs which may indicate your minerals are running low or are insufficient to keep up the function. Watch for the following signs:

  • Weakness
  • Easy fatigue
  • Pale skin
  • Constipation
  • Paresthesia of hands and feet
  • Disturbed motor function
  • Altered neurological function
  • Oral ulcers
  • Swollen tongue
  • Shortness of breath
  • Blurred vision
  • Mood changes
  • Weight loss

Additional information

Type

Injection

Feature

500mcg/1ml

Unit

amp

Formula

Mecobalamin

Composition

Mecobalamin 500 mcg / 1 ml

Brand

Sami Pharma

Prescription Required

Yes