Uristat 40mg Tablet 10 ‘S

Uristat 40mg Tablet 10 ‘S contains Febuxostat as an active ingredient.

Uristat 40mg Tablet 10 ‘S  is used to lower uric acid levels in people with Gout.

Take this medication by mouth with or without food as directed by your doctor, usually once daily.

The dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Description

Indications

Uristat 40mg Tablet 10 ‘S can be used to treat:

  • Gout 

How Does Uristat 40mg Tablet 10 ‘S Work

Uristat 40mg Tablet 10 ‘S is a xanthine oxidase inhibitor,essentially these drugs work by blocking the action of enzyme xanthine oxidase,an enzyme that breaks down purines into uric acid.Purines are found in various food items.

How To Use Uristat 40mg Tablet 10 ‘S

Uristat 40mg Tablet 10 ‘S is to be ingested orally either with or without food once daily.Preferably at the same time each day;patients are advised to set a daily alarm as a reminder to ingest Uristat 40mg Tablet 10 ‘S daily without missing a dose and at the same time each day.Patients are asked to intake at least 2 liters of water daily while undergoing treatment with Uristat 40mg Tablet 10 ‘S.

Uristat 40mg Tablet 10 ‘S is only prescribed in serious gout conditions where drugs such as allopurinol have been unsuccessful in bringing down uric acid levels.Over the counter painkillers (such as NSAIDs, eg Ibuprofen) are commonly prescribed alongside Uristat 40mg Tablet 10 ‘S as patients might experience gout flare ups for a few months or more while undergoing treatment with Uristat 40mg Tablet 10 ‘S.

Dosage

Adult Dosage

A tablet a day is most commonly prescribed to patients aged 18 years and above.Uristat 40mg Tablet 10 ‘S can be prescribed twice daily as well if need be in certain cases;the two doses are to be evenly spaced out throughout the day.

Child Dosage

Uristat 40mg Tablet 10 ‘S is not recommended to patients under the age of 18 years.

Elderly Dosage 

Patients aged 65 years and older and mostly started off at a lower dosage due to reduced kidney and liver function.

Pregnancy Use And Lactation

There isn’t enough evidence to suggest that Uristat 40mg Tablet 10 ‘S is safe to be prescribed to expectant mothers,therefore,if you are pregnant or planning to start a family while undergoing treatment with Uristat 40mg Tablet 10 ‘S,it’s best to consult a physician before ingesting any drug.Uristat 40mg Tablet 10 ‘S may pass to the infant via breastmilk and is therefore not recommended for breastfeeding mothers.

Contraindications

Please tell your doctor if you have a history of any of the following before using Uristat 40mg Tablet 10 ‘S:

  • Allergy to Uristat 40mg Tablet 10 ‘S or any other medicine or food substance 
  • Moderate to severe liver impairment/disease
  • Moderate to severe heart impairment/disease
  • Hyperuricemia due to cancer 
  • Hyperuricemia due to Lesch-Nyhan syndrome
  • Moderate to severe kidney impairment/disease
  • Patients aged 18 years or younger 

Precautions

Please tell your doctor about any of the following conditions before using Uristat 40mg Tablet 10 ‘S:

  • Mild to moderate liver impairment/disease
  • Mild to moderate heart impairment/disease
  • Skin sensitivity to drugs (especially allopurinol)
  • Mild to moderate kidney impairment/disease

Interactions With Other Medications

Please tell your doctor about the use of the following before using Uristat 40mg Tablet 10 ‘S:

  • Herbal medications 
  • Vitamins 
  • Azathioprine 
  • Mercaptopurine 
  • Theophylline 

Adverse Effects

Common Adverse Effects

Like most medicines,Uristat 40mg Tablet 10 ‘S has certain side effects which include:

  • Nausea 
  • Joint pain 
  • Gout flare-ups 
  • Skin rash 
  • Fatigue 

These effects tend to be mild and resolve in a few days of taking Uristat 40mg Tablet 10 ‘S.

Rare Adverse Effects

If any of the following adverse effects are seen or felt,the patient is advised to immediately contact their doctor.

  • Unexplained weightloss
  • Chest pain
  • Shortness of breath
  • Numbness in one side of the body

How To Cope With Some Of The Adverse Effects

  • Fatigue- Patients experiencing this adverse effect, are advised to take deep breaths,intake tea or coffee,get a good night’s rest and not to overburden themselves for a few days.
  • Nausea-Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. 
  • Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream.Apply a cold compress to the rash helps reduce itchiness and redness caused by rash.An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.

Key Facts About Uristat 40mg Tablet 10 ‘S

  • Uristat 40mg Tablet 10 ‘S is prescribed for treatment of severe gout 
  • Uristat 40mg Tablet 10 ‘S is not recommended for children under the age of 18 years 
  • Uristat 40mg Tablet 10 ‘S may cause a gout flare up in the beginning of the treatment
  • Uristat 40mg Tablet 10 ‘S is not safe to be ingested by breastfeeding women
  • Uristat 40mg Tablet 10 ‘S is commonly accompanied by painkillers at the start of the treatment

FAQs

#1.HOW TO STORE Uristat 40mg Tablet 10 ‘S?

Uristat 40mg Tablet 10 ‘S is to be kept away from the reach of children,in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.

#2.WHAT IF I TAKE TOO MUCH OF Uristat 40mg Tablet 10 ‘S?

In case of too much consumption by accident, kindly contact your doctor or nearby hospital straight away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

#3.WHAT IF I MISS A DOSE OF Uristat 40mg Tablet 10 ‘S?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next dosage time or next day, do not double the dose and take your medication as per schedule.

#4.HOW IS Uristat 40mg Tablet 10 ‘S SUPPOSED TO BE TAKEN?

Uristat 40mg Tablet 10 ‘S is to be ingested orally either with or without food once daily.Preferably at the same time each day;patients are advised to set a daily alarm as a reminder to ingest Uristat 40mg Tablet 10 ‘S daily without missing a dose and at the same time each day.Patients are asked to intake at least 2 liters of water daily while undergoing treatment with Uristat 40mg Tablet 10 ‘S.

#5.HOW DOES Uristat 40mg Tablet 10 ‘S WORK?

Uristat 40mg Tablet 10 ‘S is a xanthine oxidase inhibitor,essentially these drugs work by blocking the action of enzyme xanthine oxidase,an enzyme that breaks down purines into uric acid.Purines are found in various food items.

#6.WILL Uristat 40mg Tablet 10 ‘S AFFECT MY SEXUAL ACTIVITY?

No,there isn’t sufficient evidence to suggest that patients experience a decrease in libido.

#7.CAN I TAKE Uristat 40mg Tablet 10 ‘S DURING MY PREGNANCY?

No,Uristat 40mg Tablet 10 ‘S is deemed unsafe to be ingested during pregnancy.

#8.WHAT ARE COMMON SIDE EFFECTS CAUSED BY Uristat 40mg Tablet 10 ‘S?

  • Nausea 
  • Joint pain 
  • Gout flare-ups 
  • Skin rash 
  • Fatigue 

#9.WILL Uristat 40mg Tablet 10 ‘S AFFECT MY FERTILITY??

No,there isn’t sufficient evidence to suggest that patients experience a decrease in fertility.

#10.WHAT LAB TESTS WILL BE PRESCRIBED WHILE TREATMENT WITH Uristat 40mg Tablet 10 ‘S AND HOW OFTEN?

Liver function tests are prescribed prior to the commencement of treatment and uric acid levels are monitored periodically (especially after 2 weeks of undergoing treatment) during the course of treatment.

#11.IS IT SAFE TO HAVE PAINKILLERS WHILE TAKING Uristat 40mg Tablet 10 ‘S?

Yes.Over the counter painkillers such as paracetamol are safe to be ingested along with Uristat 40mg Tablet 10 ‘S under the supervision of a doctor.

#12.IS IT SAFE TO HAVE Uristat 40mg Tablet 10 ‘S ALONG WITH ORAL CONTRACEPTIVES?

Yes.There is no evidence to suggest that Uristat 40mg Tablet 10 ‘S interacts with oral contraceptives.

#13.WHY MUST I PROTECT MY SKIN FROM THE SUN WHILE TAKING Uristat 40mg Tablet 10 ‘S?

Treatment with Uristat 40mg Tablet 10 ‘S may lead to the skin becoming sensitive to sun damage and it is therefore recommended to patients to wear sunscreen at all times,along with hats and gloves whenever possible to protect themselves from sun damage.

#14.DOES Uristat 40mg Tablet 10 ‘S CAUSE ADDICTION?

No.This drug has shown no evidence to prove addiction of any kind in any patient.

#15.WHAT IF I FORGET TO TAKE THE Uristat 40mg Tablet 10 ‘S?

It is advised that the drug is taken at the same time each day,an alarm can be placed to remind patients to take Uristat 40mg Tablet 10 ‘S at the proper time and at least an hour before having any meal.If patient misses a dose of Uristat 40mg Tablet 10 ‘S,they should take it immediately but if the time for the next dose of the drug is near then its beneficial for patients to skip the missed dose and take the tablets as per schedule,doubling of doses has proven to cause severe side effects.

#16.IS Uristat 40mg Tablet 10 ‘S SAFE TO GIVE TO ELDERLY PATIENTS?

Yes.This drug can be easily and safely prescribed to patients above 18 years of age.For eldery patients the dosage of the drug may be lower than normal due to decreased kidney function,Uristat 40mg Tablet 10 ‘S may not be effectively removed from the body and so,in such cases the doctor may prescribe an altered dose of the Uristat 40mg Tablet 10 ‘S.

#17.CAN LIFESTYLE CHANGES HELP ME WITH MY CONDITION?

Yes.You can adopt certain healthy lifestyle changes in order to help with gout.These include quitting smoking, avoiding alcohol,eating a wholesome diet consisting of fresh vegetables and fruits with the cut down of salt, and incorporating physical activity in your daily routine.

Additional information

Type

Tablet

Feature

40mg

Unit

'S

Formula

Febuxostat

Composition

Febuxostat 40 mg

Brand

Cell Laboratories (Pvt) Ltd

Prescription Required

Yes