Maxfol 600mcg Tablet 10 ‘S

Description

About

{{Product}} contains L-methyl folate as an active agent, a form of Vitamin B, and is used to treat megaloblastic anemia, hepatic and renal impairment, depression, and manage folate deficiency.

Folate is required to produce red blood cells. Its deficiency can cause anemia, and hyperhomocysteinemia (high levels of amino acids in the blood). {{Product}} is not a medication for psychological disorders, however, it may enhance the activity of some antidepressants and antipsychotics. 

Indications

• Dietary management of impaired metabolic processes in women with nutritional requirements during high-risk recurrent pregnancy loss, Impaired folic acid absorption and metabolism, and high hyperhomocysteinemia (high levels of amino acids in the blood) during pregnancy.
• Adjunct to treatment with antidepressants.
• Hepatic and renal impairment. 
• Megaloblastic anemia (formation of large and abnormal red blood cells)

How Does Maxfol 600mcg Tablet 10 ‘S Work

{{Product}} contains l-methyl folate as an active ingredient. It is a structural analog of folic acid that is diffused in the blood, after readily transforming into its active form and producing its biological activities including anticancer activities, biosynthesis of nucleic acids on a genetic level, and acting as an adjunct to depression. L-methyl folate gives off its methyl group and inactivates the tumor-promoting genes by DNA hypomethylation. This causes a decline in the proliferation and progression of tumor cells and renders the chromosomes unstable to contribute to tumor development. 

L-methyl folate also sensitizes tumor cells to the cytotoxic effects of chemotherapeutic agents. It is also helpful in the treatment of brain tumors because of its ability to cross the blood-brain barrier, unlike folic acid. 

How To Use Maxfol 600mcg Tablet 10 ‘S

{{Product}} should be taken orally (by mouth), regardless of the meal. 

Dosage

The usual dose is one to two tablets daily. The typical dose for folic acid deficiency is 250 to 1000 mcg per day. However, the recommended dose to fulfill dietary requirements is 400mcg in adults. 

High homocysteine in the blood

• 0.5 to 5 mg per day has been used, although 0.8-1 mg per day is more effective.
• 15 mg per day has been used. Other dosage plans such as 2.5 to 5 mg thrice a week are also effective. 

Depression

7.5 to 15 mg once daily as an adjunct to antidepressant medication.

Megaloblastic Anemia

7.5 to 15 mg once daily 

Renal & Hepatic Impairment

The dose shouldn’t exceed more than 40 mg per day in cases of moderate to severe renal or hepatic impairment. 

Pregnancy And Lactation

The active agent is distributed in breast milk to fulfill the daily dietary requirement of folic acid for the infant. Intake for a prolonged period may cause a decrease in the serum levels of Vitamin B12. 

400 mcg is recommended for women of childbearing potential or should be continued through the first month of pregnancy. However, the recommended dose during pregnancy is 600mcg. 

Prevention of neural tube defects 

The dose for women with a history of pregnancy with neural tube defect is 4 mg per day before one month of conception and continued for three months after conception. 

Contraindications

• Hypersensitivity to the active agent or any of the excipients
• Known intolerance

Precautions

• {{Product}} shouldn’t be taken in doses higher than recommended. 
• {{Product}} shouldn’t be taken as monotherapy for pernicious and megaloblastic anemias, with the presence of Vitamin B12 deficiency. 
• Tell your doctor if you have a history of seizures, pernicious anemia, or bipolar disorder. 

Interactions With Other Medications

{{Product}} may show interactions with the following medications:

• Warfarin
• Birth control pills 
• Fluoxetine
• Isotretinoin
• Oral antidiabetic agents (e.g., Metformin)
• Antiepileptic agents (e.g., Valproic acid, Phenytoin)
• Isotretinoin 

Adverse Effects

• Irritability
• Disturbed sleep patterns 
• Nausea
• Abdominal distention
• Development of bitter taste 
• Flatulence

How To Cope with Some of The Adverse Effects

• Bitter Taste – Chew mint flavored or sugar-free gum. Brushing teeth after having meals, staying hydrated, and usage of non-metallic utensils are some ways to cope with a bitter or metallic taste. 
• Nausea-  Take small and frequent meals and avoid taking heavy meals. Stay in the fresh air, chew peppermint gum, or take peppermint tea. You can also take an anti-emetic if there are episodes of vomiting, after discussing it with your doctor. 
• Abdominal Distention – Your doctor may recommend you probiotics and certain enzymes that help cope with abdominal distention. Antispasmodics and low-dose laxatives are also useful. 
• Flatulence- Diet and lifestyle changes can help control flatulence such as avoiding known food that causes flatulence, taking small and frequent meals, slow drinking and swallowing, and regular exercise. 
• Disturbed Sleep Patterns – Set a bedtime and avoid taking naps during the daytime. Avoid stressful chores and drinking alcohol or caffeine before going to bed.

FAQs

1. WHAT HAPPENS IN CASE OF OVERDOSE?

The overdose of Maxfol 600mcg Tablet 10 ‘S is not likely to induce life-threatening symptoms. However, the symptoms should be reported immediately if observed. 

2. HOW LONG DOES IT TAKE FOR {PRODUCT}} TO PRODUCE THERAPEUTIC EFFECTS?

The active ingredient L-methyl folate is known to produce desired effects within 2 to 4 weeks of intake if taken in a significant dose. 

3. CAN A PREGNANT WOMAN TAKE IT?

{{Product}} is acceptable for usage in pregnancy. Also, there is no fetal risk associated with the usage of Maxfol 600mcg Tablet 10 ‘S during pregnancy. 

4. WHAT HAPPENS IF MISS THE DOSE?

{{Product}} is usually taken once daily. Take the dose any time of the day as soon as you remember. 

5. CAN I USE BLOOD PRESSURE-LOWERING MEDICATIONS ALONG WITH {{PRODUCT}}?

{{Product}} doesn’t necessarily show interactions with blood pressure lowering medicines. Monitor your blood pressure regularly and tell your doctor if you observe any changes. 

6. CAN I TAKE {{PRODUCT}} BEFORE SURGERY?

{{Product}} is safe to be taken before surgery unless not specifically prohibited.

7. IS {{PRODUCT}} SAFE TO USE IN STOMACH UPSETS?

{{Product}} is not likely to cause adverse effects on the stomach. It can be taken during stomach upsets unless not limited by your doctor.

8. WHAT ARE THE STORAGE CONDITIONS OF {{PRODUCT}}?

{{Product}} should be stored in a cool & dry place, away from direct sun exposure.