Dervit-B 50mcg/0.5mg Ointment 30 gm

Description

About

Dervit-B 50mcg/0.5mg Ointment 30 gm belongs to a class of topical medicines that is a combination of synthetic steroid (Glucocorticoid) and vitamin D derivative (calcipotriol). Dervit-B 50mcg/0.5mg Ointment 30 gm is prescribed for the treatment of inflammatory skin conditions, particularly effective against skin conditions causing plaque patches, commonly seen in Psoriasis. The application of medicines in combination has proven to be more effective as compared to treatment with a single drug. Psoriasis is a skin disease that is inflammatory and causes swelling, redness, itching, and dry flaky skin. Topical medicines can be prescribed alone or combined with oral drugs.

Dervit-B 50mcg/0.5mg Ointment 30 gm contains Betamethasone dipropionate and calcipotriol which acts by reducing inflammation exhibited by swelling and redness, as well as help control the rate of skin cells showing production in excess, this increased growth is the reason why skin appears thick in patches. Therapeutic outcomes of Dervit-B 50mcg/0.5mg Ointment 30 gm have been well-received due to its dual mode of action against inflammatory skin conditions. 

Dervit-B 50mcg/0.5mg Ointment 30 gm is available in the form of ointment or gel in a tube, meant for external use only. Dervit-B 50mcg/0.5mg Ointment 30 gm can be applied in a thin coat over the affected area on the skin with clean hands, once daily. Usually, clinical improvements can be seen in a week, but the treatment may last up to 4 weeks or as advised by your doctor. Common side effects of Dervit-B 50mcg/0.5mg Ointment 30 gm include skin rash, itching, and skin dryness. 

Indications

Dervit-B 50mcg/0.5mg Ointment 30 gm is prescribed for the management of a variety of skin conditions including:

• Psoriasis Vulgaris 

How Does Dervit-B 50mcg/0.5mg Ointment 30 gm Work?

Dervit-B 50mcg/0.5mg Ointment 30 gm is more suited for inflammatory skin conditions with concurrent patches of plaque affecting it, commonly seen in Psoriasis. It works by acting on the skin via two basic mechanisms. Firstly, Betamethasone being a Glucocorticoid controls the production of proteins that lead to inflammation by binding to Glucocorticoid receptors and interacting with DNA sequence. Also, it controls the infiltration and migration of inflammatory cells like leukocytes. It also inhibits Phospholipase A2 which speeds up the process of prostaglandin formation, a key mediator in inflammatory reactions. Dervit-B 50mcg/0.5mg Ointment 30 gm helps decrease this inflammation.

Secondly, Calcipotriol helps control the rate of production of skin cells, which in excess is causing thickened skin patches. Calcipotriol brings down this overproduction of cells.

How to use Dervit-B 50mcg/0.5mg Ointment 30 gm?

Dervit-B 50mcg/0.5mg Ointment 30 gm is available in the form of ointment or gel meant for external use only to be applied with clean hands after washing the affected skin properly and gently drying afterward. Dervit-B 50mcg/0.5mg Ointment 30 gm is safe for use in adults and adolescents 18 years of age and above. In children, safety data is not yet available. 

Available Potency and forms of Dervit-B 50mcg/0.5mg Ointment 30 gm 

Ointment – 15 g

Usage

• Wash and gently pat dry your skin before applying the Dervit-B 50mcg/0.5mg Ointment 30 gm
• Uncap the tube and pinch the foil on the mouth of the tube with a projection given on the cap
• Take out a small amount of {{product} as per fingertip units and gently rub it in to form a thin, even coat over the affected area
• Wash your hands after application (unless a condition is affecting your hands), an additional amount can be reapplied if Dervit-B 50mcg/0.5mg Ointment 30 gm gets wiped off from any part.
•  Dervit-B 50mcg/0.5mg Ointment 30 gm is applied to the skin once a day, or as per the doctor’s suggestion, avoid exposure to direct sunlight
• Avoid wrapping the area with a bandage so as not to wipe it out 
• Dervit-B 50mcg/0.5mg Ointment 30 gm must not be used on or near genitals, mouth, or any broken/open skin
• Dervit-B 50mcg/0.5mg Ointment 30 gm is applied one time a day and allows it to stay on the skin for some time. It would be better if you avoid taking a bath till a few hours after application

Dosage

Dervit-B 50mcg/0.5mg Ointment 30 gm is not used for very long periods. Treatment is generally prescribed for 2 weeks but can last up to 4 weeks depending on your condition. If there’s no improvement in your symptoms after 2 weeks, consult your doctor who may consider changing the medicine for you.

Dosage for the ointment form can be estimated as per fingertip units (fingertip of forefinger till first line/crease). While applying Dervit-B 50mcg/0.5mg Ointment 30 gm make sure it does not cover more than 30% of the total treated area. Dervit-B 50mcg/0.5mg Ointment 30 gm application in larger than required doses is not advised.

Adult Dosage

A thin film of Dervit-B 50mcg/0.5mg Ointment 30 gm is to be applied once a day, as instructed by a physician.

Small area: 1- 2 fingertip units

Large area: 4 – 5 fingertip units

Maximum daily safe dose: 15 g (equal to one tube of the same weight)

Maximum weekly safe dose: 100 g

Child Dosage

Dervit-B 50mcg/0.5mg Ointment 30 gm is not considered safe to be prescribed to patients aged below 18 years

Elderly Dosage 

For elderly patients the dosage of the drug may be lower than normal due to decreased kidney function, Dervit-B 50mcg/0.5mg Ointment 30 gm is although absorbed through the skin in insignificant amounts may pose a problem in elderly patients so, in such cases the doctor may prescribe an altered dose of the Dervit-B 50mcg/0.5mg Ointment 30 gm.

Pregnancy use and lactation

 Dervit-B 50mcg/0.5mg Ointment 30 gm should not be applied during pregnancy, therefore if you are pregnant, or are planning to conceive a baby, please do discuss Dervit-B 50mcg/0.5mg Ointment 30 gm with your doctor before using it, who will only prescribe if deemed necessary.

If you are breastfeeding an infant ask your doctor first for medicine may be secreted into breast milk in minute quantity, although topical use of Dervit-B 50mcg/0.5mg Ointment 30 gm is not known to show any harmful effects, avoid application of Dervit-B 50mcg/0.5mg Ointment 30 gm on the chest or where the baby might ingest it. With regards to safety please make sure to consult your doctor first before using it. 

Contraindications

Please inform your doctor if you have a history of any before using Dervit-B 50mcg/0.5mg Ointment 30 gm:

• Allergy to Dervit-B 50mcg/0.5mg Ointment 30 gm 
• Hypercalcemia 
• Hypervitaminosis D
• If you’re taking calcium/vitamin D supplements 
• Bacterial infection 
• Viral infection (example herpes)
• Fungal infection (for example athlete’s foot)
• Tuberculosis/syphilis
• Perioral skin rashes
• Broken/ damaged or thin skin 
• Dry scaly skin 
• Rosacea (flushed appearance of skin)
• Children and adolescents under 18 years 
• Pregnancy 
• Liver impairment 
• Inadequate Kidney function

Precautions‌ ‌

Please‌ ‌tell‌ ‌your‌ ‌doctor‌ ‌about‌ ‌any‌ ‌of‌ ‌the‌ ‌following‌ ‌conditions‌ before starting or during the treatment with ‌Dervit-B 50mcg/0.5mg Ointment 30 gm:‌ 

• If there is a history of allergy to the medicine.
• Make sure to wash your hands thoroughly before and after application, and avoid getting ‌Dervit-B 50mcg/0.5mg Ointment 30 gm in your eyes.
• Do not use ‌Dervit-B 50mcg/0.5mg Ointment 30 gm for long durations, if there is no noticeable difference in your condition after a week contact your doctor.
• If ‌Dervit-B 50mcg/0.5mg Ointment 30 gm was prescribed for prolonged use by the doctor, it may put you at risk of infections or slow wound healing due to immunosuppression, take precautions accordingly.
• Avoid applying to open wounds or cracked skin except if advised by the doctor.
• Betamethasone in ‌Dervit-B 50mcg/0.5mg Ointment 30 gm is a steroid that when used for a longer duration can cause suppression of adrenal function.
• Avoid applying to sensitive parts like inside the nose, mouth or around the mouth, and genitals. 
• Dervit-B 50mcg/0.5mg Ointment 30 gm may initially cause itching, redness, or irritation of the skin. It is suggested to contact your doctor if these symptoms persist.
• Careful application is advised, do not apply larger than required doses.
• Dervit-B 50mcg/0.5mg Ointment 30 gm is best applied on naked skin without any bandages except if advised to loosely cover it by your doctor.
• Avoid going near fire or open flames to avoid risking burns.

Interaction with other medications

Certain medications could interact with Dervit-B 50mcg/0.5mg Ointment 30 gm and may increase or decrease its absorption. Make sure to inform your doctor about all the drugs you’re currently taking, in which case, your doctor might alter the treatment. 

• Steroids (like prednisone, hydrocortisone)
• Other skin medications (you can apply such drugs at different timings)
• Cosmetics (may decrease the efficacy)
• Skin products that might irritate the skin

Adverse effects

Like most medicines, Dervit-B 50mcg/0.5mg Ointment 30 gm has some side effects which include:

Common Side effects

• Itching/ pruritus
• Redness
• Dryness of skin 
• Flaky skin
• Tingling/ burning sensation at the site of application

Rare side effects

• Anaphylactic reaction
• Worsening of symptoms
• Headache 
• Blurred vision
• Pustules on skin
• Dizziness 
• Blistering
• Temporary exacerbation of symptoms
• High intraocular pressure in eyes (if used in large amounts / near the eyes) 

List Of How to Deal with Adverse Effects

• Allergic Reactions – Allergic reactions to the drug may be mild to severe or potentially could be life-threatening. If allergy is suspected immediately take anti-allergy (antihistamine) medicine which will stop the mild reaction. If a serious allergic reaction is suspected rush to the nearby hospital and avoid Dervit-B 50mcg/0.5mg Ointment 30 gm and drugs with similar compounds in the future.
• Skin Rash/ Blisters – can be eased by applying soothing and healing lotions or creams such as calamine or organic aloe vera lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Dryness – apply a moisturizer to the skin and wait for 10-15 minutes after which apply Dervit-B 50mcg/0.5mg Ointment 30 gm onto the skin. This will prevent skin from getting dry and flaky.
• Headaches – In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
• Feeling or being sick (nausea or vomiting) or diarrhea – Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. 
• Feeling dizzy (lightheaded) or weak – If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Blurred vision- This side effect tends to go away on its own in a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.

FAQs

# 1. HOW TO STORE Dervit-B 50mcg/0.5mg Ointment 30 gm?

Dervit-B 50mcg/0.5mg Ointment 30 gm is to be kept away from the reach of children, in a cool dry place above 25°C, away from direct sunlight and humidity as that tends to change the chemical nature of certain drugs.

# 2. WHAT IF I USE TOO MUCH OF Dervit-B 50mcg/0.5mg Ointment 30 gm?

In case of excessive usage or accidental ingestion, kindly contact your doctor or nearby hospital right away. The amount of medication that can result in severe side effects varies from person to person. Toxicity in general results in severe abdominal pain, slowing down of heart rate, and difficulty in breathing accompanied by dizziness and fainting spells.

# 3. HOW IS Dervit-B 50mcg/0.5mg Ointment 30 gm SUPPOSED TO BE TAKEN?

Dervit-B 50mcg/0.5mg Ointment 30 gm is available in ointment or gel form to be applied topically only over the affected area

# 4. CAN I USE OTHER SKINCARE Dervit-B 50mcg/0.5mg Ointment 30 gm?

In case you want to use other skin creams or ointments, make sure you use those products at a different time. Tell your doctor about the items you want to use to ascertain their safety. Avoid applying make-up as well when using Dervit-B 50mcg/0.5mg Ointment 30 gm where makeup is to be applied

# 5. CAN I TAKE Dervit-B 50mcg/0.5mg Ointment 30 gm DURING PREGNANCY?

Dervit-B 50mcg/0.5mg Ointment 30 gm should not be used in pregnancy due to potentially harmful effects on the unborn baby. Breastfeeding mothers should practice caution and avoid applying cream on or near breasts. Consult your doctor regarding the safety of Dervit-B 50mcg/0.5mg Ointment 30 gm first in case of pregnancy as well as breastfeeding.

#6. WILL Dervit-B 50mcg/0.5mg Ointment 30 gm AFFECT MY FERTILITY?

No, there isn’t sufficient evidence to suggest that patients experience a decrease in fertility.

# 7. CAN I TAKE Dervit-B 50mcg/0.5mg Ointment 30 gm WHILE BREASTFEEDING?

With regards to safety please make sure to consult your doctor first before using it. Although topical use of Dervit-B 50mcg/0.5mg Ointment 30 gm is not known to show any harmful effects, avoid application of Dervit-B 50mcg/0.5mg Ointment 30 gm on the chest or from where the baby might ingest it.

# 8. CAN Dervit-B 50mcg/0.5mg Ointment 30 gm CAUSE DIZZINESS? IF SO, HOW SHOULD I MANAGE IT?

No, in general Dervit-B 50mcg/0.5mg Ointment 30 gm does not cause dizziness but may occur as a rare side effect or may experience blurred vision. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during your treatment, as it may worsen the dizziness.

# 9. FOR HOW LONG WILL I HAVE TO CONTINUE TAKING Dervit-B 50mcg/0.5mg Ointment 30 gm?

It is generally prescribed as once a day application. Treatment can last from 2 weeks up to 4 weeks depending on your condition and response to the cream. Don’t use Dervit-B 50mcg/0.5mg Ointment 30 gm for more than a week unless your doctor tells you to.

# 10. IS IT SAFE TO HAVE PAINKILLERS ALONGSIDE Dervit-B 50mcg/0.5mg Ointment 30 gm?

Yes, painkillers are safe to be ingested along with Dervit-B 50mcg/0.5mg Ointment 30 gm 

# 11. CAN I GO OUTSIDE AFTER APPLYING Dervit-B 50mcg/0.5mg Ointment 30 gm?

Commonly Dervit-B 50mcg/0.5mg Ointment 30 gm is prescribed to be applied once a day. You can apply it at bedtime to avoid sun or UV exposure. If it is necessary to step outside, make sure to protect your skin from the direct sun via shades or clothing. 

# 12. WHAT IF AFTER APPLICATION OF Dervit-B 50mcg/0.5mg Ointment 30 gm I DEVELOP ITCHING OR REDNESS?

This could be a sign of an allergic reaction. You should immediately wash off the medicine with copious amounts of water. If these symptoms do not settle down, contact your doctor at once.

# 13. WHAT IF I MISS A DOSE?

Dervit-B 50mcg/0.5mg Ointment 30 gm is generally prescribed as a one-time application per day. If you have missed a dose, apply it as soon as you remember, but in case it is nearly time (less than 12 hours) for the next dose do not try to make up for the missed one.