Articure Injection 2 ml

Articure Injection 2 ml is a pain relieving medication for treating postoperative pain from orthopaedic, dental procedures, lower back pain, pain from Injury or swelling.

Articure Injection 2 ml is chemically composed of Diclofenac Sodium and Lidocaine.

Articure Injection 2 ml is injected intramuscular injection in dosage prescribed by doctor usually once a day. 

It is not recommended during pregnancy, especially  during the last trimester of pregnancy.

Drug category: Analgesic

Description

About

Articure Injection 2 ml is available as a combination of a nonsteroidal anti-inflammatory (NSAID) drug (Diclofenac sodium) and a local anesthetic agent (lidocaine). Articure Injection 2 ml is used to relieve all levels of pain and inflammation In a wide range of illnesses such as osteoarthritis, rheumatoid arthritis, periarthritis (frozen shoulder), acute gout, fracture, low back pain, etc. Lidocaine in the Articure Injection 2 ml helps to alleviate discomfort in the injection site which could be a side effect of diclofenac sodium in the medicine.

Articure Injection 2 ml is available in liquid form that is injected into the patient’s vein (intravenously) by a trained health care professional or a nurse in a medically equipped facility.  A low dosage of this medicine is usually recommended for elderly and debilitated patients In proportion to one’s age and physical condition.

Dosage is largely determined by the patient’s reaction to the product as well as any side effects seen during therapy. Dosage should not be raised or decreased without consulting a physician, and the product should only be used for the period prescribed.

Articure Injection 2 ml may produce certain side effects such as soreness on the injection site, nausea, vomiting, gastrointestinal discomfort, bleeding, local necrosis, and abscesses (in isolated cases).

Indications

Articure Injection 2 ml is used to relieve pain and inflammation in:

  1. Arthritic conditions: such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile chronic arthritis, acute gout.
  2. Acute musculoskeletal disorders: such as tendinitis, frozen shoulder (periarthritis, tenosynovitis, and bursitis.
  3. Other traumatic conditions that cause discomfort or pain: such as fractures, low back pain, sprains, and strains, renal colic and postoperative pain, and relieve pain and inflammation related to orthopedic, dental, and other minor surgeries.

How Does Articure Injection 2 ml Work

Diclofenac’s action seems to be linked to the suppression of prostaglandin production. By inhibiting cyclooxygenase, an enzyme that catalyzes the generation of prostaglandin precursors from arachidonic acid, diclofenac may limit prostaglandin synthesis. Lidocaine works faster and lasts longer than most other local anesthetics by inhibiting nerve impulse production and conduction by delaying depolarization.

How To Use Articure Injection 2 ml: 

Articure Injection 2 ml is available in liquid/injectable form, the anesthetic is administered into a patient’s vein (intravenously) by a trained healthcare professional or nurse usually 1-2 times a day.

  • Diclofenac sodium is a strong analgesic and antipyretic nonsteroidal anti-inflammatory medication (NSAID) which possesses uricosuric properties as well. 
  •  Within half an hour of injection with Diclofenac acid, the plasma concentration reaches its peak. 
  • Lidocaine Hydrochloride has a faster onset of anesthesia and a shorter duration of 1-2 hours. 

Dosage

Articure Injection 2 ml is available in solution form.

Form and strength:

75mg/2ml

20mg/2ml

Adult dosage:

Intramuscular injection of one ampoule once a day (or twice a day in severe instances). 

Child Dosage:

Articure Injection 2 ml containing 1-3 mg diclofenac/kg body weight daily in split doses in children with juvenile chronic arthritis.

Elderly Dosage:

A low dosage of this medicine is usually recommended for elderly and debilitated patients In proportion to one’s age and physical condition.

Renal Colic Patients:

Once a day, inject one ampoule intramuscularly. If necessary, a second ampoule might be given after 30 minutes. 

Pregnancy and Lactation

Unless there are strong reasons, it should not be administered during pregnancy. It’s best to utilize the smallest dose that works. These medications are not advised during the third trimester of pregnancy. 

Although very minute amounts of Articure Injection 2 ml may be found in breast milk, no adverse effects on the newborn are envisaged. 

Contraindications

Before using Articure Injection 2 ml, consult your doctor if you have a medical history of any of the following:

  • Allergic to Articure Injection 2 ml and its contents, or any food product (such as pork, beef, etc)
  • Gastrointestinal bleeding
  • Peptic ulcer
  • Patients whose attacks of asthma, urticaria, or acute rhinitis are precipitated by aspirin or any other NSAIDs.
  • Patients who are hypersensitive to amide-type local anesthetics, though this is a relatively uncommon occurrence. 
  • Patients with Adams stokes syndrome
  • Patients with severe degrees of AV, SA, or intraventricular heart block in absence of an artificial pacemaker.

Precautions

Please tell your doctor about any of the following conditions before using {{product}:

  • Patients with severe hepatic, cardiac, or renal insufficiency, as well as the elderly, should be closely monitored because NSAIDs might cause the renal function to deteriorate. 
  • Renal function should be evaluated and the lowest effective dose should be utilized. 
  • Articure Injection 2 ml should be stopped if abnormal liver function tests persist or worsen, clinical signs or symptoms suggestive of the liver disease emerge, or if additional abnormalities (eosinophilia, rash) appear. 
  • As a precaution, all patients using NSAIDs over an extended period of time should be closely followed (e.g., renal, hepatic function, and blood counts). 

Interactions With Other Medications

Consult your doctor about the use of the following medicines before using Articure Injection 2 ml:

  • Lithium
  • Digoxin
  • Anticoagulants
  • Antidiabetic agents
  • Cyclosporin
  • Methotrexate
  • Quinolone antimicrobials
  • Diuretics
  • Other NSAIDs and steroids

This document does not contain all probable drug reactions, it is advisable to keep a list of medicines in use and discuss it with your doctor ( this includes prescription/nonprescription and herbal products). 

Adverse Effects

Common Adverse Effects

Following side effects may not require immediate medical attention until becomes troublesome:

  • Gastrointestinal discomfort
  • Upper abdominal pain
  • Nausea 
  • Diarrhea
  • Drowsiness
  • Dizziness disorientation
  • Confusion
  • Lightheadedness
  • Skin rash 
  • edema

Rare Adverse Effects

Because Articure Injection 2 ml may induce serious and fatal infusion responses followed by cardiac collapse, the following side effects may require rapid attention and report to your doctor.  

  • Injection site reactions 
  • NSAIDs may raise the risk of major cardiovascular thrombotic events, myocardial infarction, and stroke, all of which are potentially fatal. With continued use, this risk may increase. 
  • Abscesses 
  • Local necrosis
  • Depressed respiratory rate
  • GastroIntestinal bleeding
  • Acute renal failure
  • Hypertension

How To Cope With Some Of The Adverse Effects

  • Feeling drowsy -If the medication makes you feel drowsy or sleepy, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Feeling or being sick (nausea or vomiting) or diarrhea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. 
  • Feeling dizzy (lightheaded) or weak –If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Soreness at the site of injection- a cold compress can be used for 5 minutes to ease out the soreness.
  • Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.

Key Facts About Articure Injection 2 ml

  • Articure Injection 2 ml is available as a combination of a nonsteroidal anti-inflammatory (NSAID) drug (Diclofenac sodium) and a local anesthetic agent (lidocaine). 
  • Articure Injection 2 ml is used to relieve all levels of pain and inflammation In a wide range of illnesses such as osteoarthritis, rheumatoid arthritis, periarthritis (frozen shoulder), acute gout, fracture, low back pain, etc. 
  • If you’re going to use this medicine on a wound or a cut, avoid using it. 
  • Talk to your doctor if you can’t tolerate any of the medicine’s adverse effects or develop any rare but serious side effects, such as seizures.

FAQs

  • What is Articure Injection 2 ml composed off?

Articure Injection 2 ml contains Diclofenac sodium and lidocaine as active ingredients.

  • How to store Articure Injection 2 ml?

Store in a dry area at a temperature of not more than 30°C. Protect Articure Injection 2 ml from the sun’s rays.

  • Can I take Articure Injection 2 ml during my pregnancy?

Articure Injection 2 ml should be avoided during pregnancy and should not be taken unless there is an extreme condition. These medications are not advised during the third trimester of pregnancy.

  • What if I take too much of Articure Injection 2 ml?

In case of too much consumption by accident, kindly contact your doctor or nearby hospital right away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

  • What if I miss a dose of Articure Injection 2 ml?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next dosage time or the next day, do not double the dose and take your medication as per schedule.

  • What lab tests will be prescribed while treatment with Articure Injection 2 ml and how often?

The physician is likely to prescribe lab tests to monitor the patient’s blood glucose levels, kidney functions, liver functions, and blood pressure levels while taking NSAID-based medications.

  • Can Articure Injection 2 ml cause dizziness? if so, how should I manage it?

Yes. It can cause dizziness as one of the most common side effects. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during the course of your treatment, as it may worsen the dizziness.

  • Can i consume alcohol with Articure Injection 2 ml?

Alcohol is known to make people dizzy, thus when combined with medication, it might cause significant dizziness. It’s recommended to stay away from alcohol while you’re getting therapy.

  • Can I drive after taking this medication?

This medication is known to make you dizzy hence, if that happens kindly avoid driving or operating any heavy machinery.

  • Is it normal to feel lightheaded after getting injected with Articure Injection 2 ml?

Yes, If Articure Injection 2 mlmakes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.

  • Will Articure Injection 2 ml affect my fertility??

No, there isn’t sufficient evidence to suggest that patients experience a decrease in fertility.

  • What dietary instructions are to be followed when using Articure Injection 2 ml?

 Continue to eat normally until your doctor tells you to switch to a specific diet.

                               

Additional information

Type

Injection

Feature

2 ml

Unit

ml

Formula

Diclofenac Sodium

Composition

Lidocaine 20 mg / 2 ml + Diclofenac Sodium 75 mg / 2 ml

Brand

Global Pharmaceuticals (Pvt) Ltd

Prescription Required

Yes