Ferti-M 150IU Injection 1 vial

Description

About

Reproductivity is a coordinated ability of the human body because of a balance between hormones released naturally and certain other factors. Hormones that are key to fertility include HCG and follicle-stimulating hormone (FSH) and luteinizing hormone (LH), serving an important function in conception and maintenance of pregnancy. For conditions due to a lack of these hormones resulting in fertility problems, they can be given as an exogenous source. Ferti-M 150IU Injection 1 vial is a potent hormone-based drug that belongs to a class of medicines called Menotropins used to treat various conditions causing fertility problems in both men and women or to aid the conception process such as in IVF procedures.

Ferti-M 150IU Injection 1 vial is chemically composed of Human Menopausal Gonadotropin (HMG) which offers dual action on both FSH receptors as well as LH receptors. By its action, Ferti-M 150IU Injection 1 vial helps the growth and maturation of follicles in female ovaries, crucial to fertility. Moreover, it plays a key role in the formation of steroidal hormones like estrogen and testosterone. Overall Ferti-M 150IU Injection 1 vial enhances the fertility of women struggling to conceive and in males improving sperm count and motility among other benefits. It is commonly followed by HCG therapy to stimulate the release of mature eggs for fertilization. The frequency of intake and duration depends on the condition under treatment. 

Ferti-M 150IU Injection 1 vial is available in the form of a dry powder and a liquid in a separate glass container to be combined in an appropriate ratio to form an injectable solution. An injection is to be given directly into the muscles or underneath the skin as advised by the doctor. Dosage of Ferti-M 150IU Injection 1 vial depends on the nature of the condition, the patient’s response to the medicine, age, and comorbidities. It can be safely administered to adult men and women but is not suggested for use in children. Where these hormones support pregnancy and increase the chance of conception, Ferti-M 150IU Injection 1 vial should not be taken once pregnancy starts, due to the lack of relevant data on pregnant humans. Animal studies reveal birth defects with its use. And use by lactating women without a doctor’s consult is not suggested. Common side effects of this medication are pain at the site of injection, headache, dizziness, mood changes, fatigue, abdominal pain, and others. 

Indications

Ferti-M 150IU Injection 1 vial is prescribed to adult males and females  to treat:

• Primary and secondary amenorrhea 
• Hypomenorrhea
• Anovulatory menstruation 
• Endocrinal disorders like Chiari-Frommel or Sheehan symptoms (pituitary necrosis after childbirth)
• Hypogonadotropic hypogonadism in males
• Asthenospermia/ oligospermia 

How does Ferti-M 150IU Injection 1 vial work

Ferti-M 150IU Injection 1 vial is chemically composed of Human Menopausal Gonadotropin (HMG) which offers dual action on both FSH receptors as well as LH receptors. By its action, Ferti-M 150IU Injection 1 vial helps the growth and maturation of follicles in female ovaries, crucial to fertility. Moreover, it plays a key role in the formation of steroidal hormones like estrogen and testosterone. Overall Ferti-M 150IU Injection 1 vial enhances the fertility of women struggling to conceive and in males improving sperm count and motility among other benefits. 

How to use Ferti-M 150IU Injection 1 vial

It is given as a subcutaneous injection or mostly injected into the muscles by a healthcare professional, in dosage as prescribed by your doctor. Dosage is completely dependent on age, weight, the severity of the condition, and the patient’s response to the medicine. Your doctor may vary your dosage accordingly. A new, sterile syringe must always be used and properly discarded following universal protocol for sharps disposal. Always start by cleaning your hands and the area to be injected. Carefully first check the glass vials to rule out any particulate matter in the solution. 

When Ferti-M 150IU Injection 1 vial is to be self-administered, the “at-home” SC/intramuscular injection technique can be taught to patients and healthcare providers. These hormonal shots can be given on the side of the arm, or mostly upper buttocks just below the hip bone (IM), subcutaneous injections can be given on the lower tummy below the navel or front thigh. Make sure you understand the right technique or get a healthcare provider to understand if you are unable to do it on your own.

It comes packed in two separate glass containers, one with dry powder and one containing the solution. A new sterile syringe is used to withdraw the solution from the liquid vial and carefully transferred to a vial containing powder to form an injectable solution. Read the label carefully to know the exact ratio before reassembling the contents into a solution form. It is advised not to shake the vials since it creates air bubbles in the liquid. After withdrawing the solution for injection gently tap the syringe and discard the first few drops to eliminate air bubbles.  Moreover, do not use the same site for injections, the next dose must be administered at least 1 inch away from the previous site. 

Available Potency and form of Ferti-M 150IU Injection 1 vial 

• 75 IU   – Ampoules 
• 150 IU – Ampoules 

Dosage

Adult Dose

Ovulation in females

The course of treatment: Not more than 12 days

50 IU Intramuscular or subcutaneous injection for the first 5 days of treatment; dose adjustment may be done no sooner than 2 days in increments of 75 – 150 IU per adjustment

Maximum Safe Dose: Do not give more than 450 IU/dose

Treatment with menotropins is commonly followed by an HCG shot (in prescribed doses) as a supporting drug  with menotropins, 1 day after the last dose of Ferti-M 150IU Injection 1 vial 

Assisted Reproductive Technology (ART)/ IVF

The dose and treatment approach varies from patient to patient

The course of treatment: Not more than 20 days

Along with GnRH agonist:

Given 2 weeks after starting of GnRH agonist: 225 IU 

If Ferti-M 150IU Injection 1 vial is given as a combination drug with urofollitropin,

Starting Dose: Do not give more than 225 IU in total (combined potency of both drugs) 

Along with GnRH antagonist:

Start Ferti-M 150IU Injection 1 vial on the 2nd or 3rd day of the menstrual cycle

Starting Dose: 150 – 225 IU every day for 5 days

After 5 days adjust the dose depending on the patient’s response and monitoring follicular growth. The titration should be done  in increments of not more than 150 IU per dose

Maximum Safe Dose: Do not give more than 450 IU/dose

After evaluation of follicle development via ultrasound, clinical examination, and serum levels of estrogen/progesterone when desired follicular growth is achieved, an additional shot of HCG is given usually a day’s gap after the last dose of  Ferti-M 150IU Injection 1 vial.

Male Fertility

In men with oligozoospermia (low sperm count),

The course of treatment: 2 to 3 months

75 to 150 IU of Ferti-M 150IU Injection 1 vial, to be injected 2 to 3 times every week

Child dosage

Ferti-M 150IU Injection 1 vial is not suggested for use in children

Elderly dose

Ferti-M 150IU Injection 1 vial is a fertility-boosting medicine, consult a doctor 

Pregnancy use and lactation

Ferti-M 150IU Injection 1 vial is used to increase your chances of getting pregnant and improve fertility before conception. It has shown adverse effects on the unborn baby in studies and trials conducted on animals, therefore it is not advised for intake during pregnancy. If you are pregnant or think you may be pregnant, please consult your doctor. Also Ferti-M 150IU Injection 1 vial may be secreted into human milk, if you are breastfeeding, please consult your doctor before taking it.

Contraindications

Please inform your doctor if you have a history of any before using Ferti-M 150IU Injection 1 vial:

• Allergic reaction to Ferti-M 150IU Injection 1 vial
• Pituitary gland tumor 
• Tumor in Hypothalamus 
• Ovarian/uterine tumor
• Ovarian cysts 
• Abnormal bleeding from the vagina
• Premature menopause 
• Anatomic disorders of the reproductive system 
• Hysterectomy
• Pregnancy 
• Breastfeeding mothers 
• Children 
• Primary testicular failure 

Precautions

Please tell your doctor about any of the following conditions before using Ferti-M 150IU Injection 1 vial:

• Ferti-M 150IU Injection 1 vial must be used with caution if you have a history of drug-related allergies
• Adequacy of liver and kidney functions must be ensured. accumulation of fluid in body spaces can occur, exhibited in the form of edema/swelling. Caution is advised especially if you have a kidney condition
• Selection criteria for the patients are important. Ferti-M 150IU Injection 1 vial can lead to overly stimulated ovaries if not administered properly
• Before starting Ferti-M 150IU Injection 1 vial, FSH and LH levels in the blood should be checked first. 
• If you are suffering from conditions like adrenocortical deficiency, or hypothyroidism, tumors associated with pituitary glands, etc. will be treated first 
•  Where Ferti-M 150IU Injection 1 vial is known to support and increase the likelihood of pregnancy, it is not safe to take once pregnancy begins. Breastfeeding mothers should also consult their doctors first
• In the fertility treatment of women with menotropins, the chances are that women may conceive more than one baby (twins/triplets). Discuss with your doctor 
• Chances of ectopic pregnancy and miscarriages are also prominent with such fertility treatments. Discuss all the details with your doctor
• Alcohol intake and smoking should be restricted. Alcohol can affect the ovulation cycle and cause pregnancy-related problems 
• It is important to monitor Basal body temperature, estradiol serum levels, and ultrasound among other tests to determine the function of ovaries and ovulation. Hyperfunctioning ovaries must be intercepted by your doctor
• Make sure to inform your doctor if you suffer from bleeding disorders, heart conditions, or other reproductive issues 

Interaction with other medications

Certain medications and laboratory-based tests could interact with Ferti-M 150IU Injection 1 vial. Make sure to provide a complete list of diseases and medicines you are currently taking to your doctor.   Ferti-M 150IU Injection 1 vial can interact with:

• Ganirelix 
• Alcohol 
• Certain laboratory tests

Adverse Effects

Common Side Effects

• Soreness at the injection site
• Nausea 
• Vomiting 
• Diarrhea 
• Headache
• Weight gain 
• Abdominal pain 
• Edema 
• Pelvic pain 
• Irritability 
• Fatigue 

Less Common Side Effects

• Anaphylactic reaction
• Skin rash 
• Restlessness 
• Breast pain 
• Breast enlargement in men 
• Palpitations  
• Ovarian torsion/twisting 
• Muscular pain / joint pain 
• Skin rash 
• Chest tightness 
• Wheezing 
• Cerebral thrombosis 
• Mental confusion 
• Visual disturbances 
• Ectopic pregnancy 
• Tachypnea 

How to cope with some of the adverse effects

• Fatigue – Patients experiencing this adverse effect are advised to take deep breaths, intake tea or coffee, get a good night’s rest, and not overburden themselves for a few days.
• Soreness at the site of injection – A cold compress can be used for 5 minutes to ease out the soreness.
• Diarrhea – Keep yourself hydrated by having lots of fluids and if the problem persists, consult your doctor before taking any medication for vomiting and diarrhea
• Headaches – In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
• Feeling or being sick (nausea or vomiting) – Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water.
• Skin Rash – Can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash helps reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Blurred vision – This side effect tends to go away on its own if a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.
• Muscular Aches and Pains – A hot or cold compress can be placed at the area of discomfort to bring relief; an over-the-counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.

FAQs

#1. WHAT EXACTLY DOES Ferti-M 150IU Injection 1 vial DO?

Ferti-M 150IU Injection 1 vial is a hormone-based medicine that is used to increase your chances of getting pregnant and improve fertility before conception. It helps by releasing mature eggs from the female ovary and in males increases the sperm count. 

#2. HOW LONG WILL I HAVE TO TAKE Ferti-M 150IU Injection 1 vial FOR?

The duration for using Ferti-M 150IU Injection 1 vial depends on the nature of your condition. It is usually taken for prolonged periods or until desired results are achieved, often combined with other drugs too. The exact duration will be decided by your doctor. 

#3. CAN I STOP TAKING  Ferti-M 150IU Injection 1 vial?

Do not just stop taking the medicine unless advised to do so, make sure to complete your treatment. Stopping it will result in unresolved fertility problems or other hormonal issues.

#4. CAN I DRINK ALCOHOL WITH  Ferti-M 150IU Injection 1 vial?

Avoid consuming alcohol when taking Ferti-M 150IU Injection 1 vial to prevent the risk of adverse effects since it is known to interact with medicine. Alcohol intake and smoking should be restricted. Alcohol can affect the ovulation cycle and pregnancy-related problems.

#5. WHAT IF I TAKE TOO MUCH OF Ferti-M 150IU Injection 1 vial?

Ferti-M 150IU Injection 1 vial is mostly administered by a healthcare professional so it is unlikely to overdose unless mismanaged. At home if you take an injection by yourself and if you have accidentally taken an extra amount, contact your doctor immediately.

#6. WHAT IF I FORGET TO TAKE  Ferti-M 150IU Injection 1 vial?

Generally, it is taken a couple of times a week or on alternate days, or a daily basis depending on your condition under treatment. If you forget to take your shot on time, take it as soon as you remember unless it is almost time for the next dose, or ask your doctor about the minimum gap between doses. 

#7. CAN I TAKE  Ferti-M 150IU Injection 1 vial DURING PREGNANCY OR BREASTFEEDING?

If you are pregnant, please consult your doctor before using Ferti-M 150IU Injection 1 vial as it carries a risk of adverse effects on the unborn baby. If you are breastfeeding, please consult your doctor before taking Ferti-M 150IU Injection 1 vial as it may get secreted into the human milk.

#8. Can I RIDE OR DRIVE AFTER TAKING {{the product}}?

Generally Ferti-M 150IU Injection 1 vial doesn’t affect your concentration, so you can drive or ride a bike while you’re taking it. But if you are feeling dizzy or unwell avoid such activities. Take safety measures to avoid potential injuries.

#9. HOW SHOULD Ferti-M 150IU Injection 1 vial BE STORED?

Keep the medicine in a cool, dry place, away from direct sunlight at 20  to 25°C, do not freeze. Make sure it is not consumed by pets, children, and other people. Dispose of unused medicine.

#10. WILL I HAVE TO UNDERGO ANY TESTS?

Your doctor will prescribe several fertility tests before starting Ferti-M 150IU Injection 1 vial and during the treatment as well. These could include blood tests, semen analysis for male patients’, thyroid, prolactin levels, FSH, LH serum levels, progesterone/estrogen levels, basal body temperature in females, ultrasound, pelvic examination, and other tests when indicated.