Co-Depricap 6mg+25mg Capsule 7 ‘S

Co-Depricap 6mg+25mg Capsule 7 ‘S is prescribed for the treatment of bipolar disease, major depressive disorder, schizophrenia and similar illnesses

Co-Depricap 6mg+25mg Capsule 7 ‘S contains olanzapine and fluoxetine 

Co-Depricap 6mg+25mg Capsule 7 ‘S is commonly prescribed to patients aged 18 years and above 

Co-Depricap 6mg+25mg Capsule 7 ‘S is to be taken orally (via mouth)

A box of 14 capsules of Co-Depricap 6mg+25mg Capsule 7 ‘S come packaged and sold separately.

 

Categories: , ,
Type

Capsule

Feature

6mg+25mg

Unit

'S

Formula

Olanzapine

Composition

Olanzapine 6 mg + Fluoxetine 25 mg

Brand

Nabiqasim Industries(Pvt) Ltd

Prescription Required

Yes

How to use, Side effects, Uses, Formula & Composition

About

Co-Depricap 6mg+25mg Capsule 7 ‘S is a combination drug that belongs to a class of medicines called “antidepressants” used to treat depression associated with bipolar disorder, in patients who do not effectively respond to antidepressants. Co-Depricap 6mg+25mg Capsule 7 ‘S is chemically composed of Fluoxetine (selective Serotonin reuptake inhibitors) and olanzapine (antipsychotic), used to treat disorders like schizophrenia and bipolar disorder.

Co-Depricap 6mg+25mg Capsule 7 ‘S works by increasing the levels of certain neurotransmitters in the brain responsible for emotional well-being in our body. If the levels of noradrenaline and serotonin, also known as “Mood elevator/stabilizer” are running low, it may lead to depression, anxiety, and mood swings. Another chemical released by brain cells is dopamine, associated with a sense of motivation, reward, and satisfaction. All of this causes major depression in case of decreased amount. 

It is available on prescription, as capsules, to be strictly used under a doctor’s supervision. Co-Depricap 6mg+25mg Capsule 7 ‘S has a slow onset of therapeutic effects which may take up to 4-6 weeks before any improvement in symptoms is evident. 

Dosage of Co-Depricap 6mg+25mg Capsule 7 ‘S depends on age, the severity of the condition, the patient’s response to the medicine, and their comorbidities. Co-Depricap 6mg+25mg Capsule 7 ‘S can be safely prescribed to adults,  children 10 years and above, elderly (65 years of age)

Abrupt withdrawal of Co-Depricap 6mg+25mg Capsule 7 ‘S can cause withdrawal symptoms for which reason it is tapered down gradually before stopping the treatment altogether. Common side effects of this medication are nausea, headache, dryness in the mouth, sleepiness, and dizziness.

Patients undergoing therapy with antidepressants should be closely monitored initially for some time to rule out worsening of symptoms.

Indications

Co-Depricap 6mg+25mg Capsule 7 ‘S is prescribed to adults and children (8 years and above)above and it is used in the treatment of:

  • Major depressive disorder associated with bipolar disorder
  • History of failed therapy with other antidepressants 
  • History of drug resistance to other antidepressants

How does Co-Depricap 6mg+25mg Capsule 7 ‘S work?

Co-Depricap 6mg+25mg Capsule 7 ‘S is prescribed to improve emotional imbalance and behavior. Co-Depricap 6mg+25mg Capsule 7 ‘S works by increasing the levels of certain neurotransmitters in the brain responsible for emotional well-being in our body. If the levels of noradrenaline and serotonin are also known as “Mood elevator/stabilizers running low, it may lead to depression, anxiety, and mood swings. Another chemical released by brain cells is dopamine, associated with a sense of motivation, reward, and satisfaction. All of this causes major depression in case of decreased amount. 

How to use Co-Depricap 6mg+25mg Capsule 7 ‘S?

Co-Depricap 6mg+25mg Capsule 7 ‘S is available in the form of capsules. Swallow the capsules with a glass of water without chewing. In general, the treatment with Co-Depricap 6mg+25mg Capsule 7 ‘S is started at the lowest effective dose which is gradually increased over weeks as tolerance develops.

 Co-Depricap 6mg+25mg Capsule 7 ‘S is usually prescribed to be taken once a day usually in the evenings, for depression and bipolar-related anxiety problems. Tolerance is common to develop with such drugs, dosage is titrated accordingly to match the therapeutic dose.

It can be taken with or without food, preferably around the same time each day. Taking higher doses of Co-Depricap 6mg+25mg Capsule 7 ‘S or more often than prescribed will not make it more effective and may increase side effects. Moreover, withdrawal symptoms can occur if the drug is stopped abruptly, therefore it must be gradually tapered down over weeks to months before stopping completely. 

Available Potency of Co-Depricap 6mg+25mg Capsule 7 ‘S 

Capsules – 6/25mg 

Dosage

Adult dose

Starting dose 6/25 mg, once a day orally (Olanzapine/Fluoxetine)

(Maximum safe dose 12/50 mg per day)

Pediatric dose 

Co-Depricap 6mg+25mg Capsule 7 ‘S  can be safely prescribed to children and adolescents 10-17 years old. Child dose depends on weight and health status, commonly starting dose is 3/25 mg (Olanzapine/Fluoxetine)

10 years old and above: 3/25 mg/ day, once orally

Maximum safe dose: 12/50 mg per day, once orally

Elderly Dose

Starting dose 6/25 mg, once a day orally (Olanzapine/Fluoxetine)

A lower dose of 3/25 mg is given to patients who are at risk of low blood pressure and other systemic irregularities. Moreover, caution must be exercised in patients with dementia associated with psychosis, in which case there is a high risk of stroke and other neurological complications. Dose adjustment is required in patients with chronic liver conditions or inadequacy. 

IMPORTANT: Initially all the starting doses are kept low which may be increased gradually over weeks as per requirement.

Pregnancy use and lactation

Co-Depricap 6mg+25mg Capsule 7 ‘S is FDA pregnancy risk category C (Harmful to the fetus in animal studies ), therefore it should not be taken during pregnancy unless the benefits outweigh the risks. If you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor before using Co-Depricap 6mg+25mg Capsule 7 ‘S. If you are breastfeeding, please consult your doctor before taking Co-Depricap 6mg+25mg Capsule 7 ‘S.

Contraindications

Please inform your doctor if you have a history of any before using Co-Depricap 6mg+25mg Capsule 7 ‘S:

  • Allergic reaction to Co-Depricap 6mg+25mg Capsule 7 ‘S or other SSRIs – indicated by skin rash, swelling around the face area, wheezing, chest tightness, and breathing difficulty
  • Have a history of taking MAO inhibitors (e.g., isocarboxazid, phenelzine, selegiline, tranylcypromine) in the last 14 days
  • Dementia associated with bipolar disorder
  • Kidney impairment
  • Liver impairment
  • Glaucoma
  • Patients with suicidal tendencies

Precautions

Please tell your doctor about any of the following conditions while using Co-Depricap 6mg+25mg Capsule 7 ‘S:

  • Co-Depricap 6mg+25mg Capsule 7 ‘S can alter platelet count in the blood which may put you at risk of easy bruising, nosebleeds
  • Elderly patients must practice caution due to age-related conditions
  • There may be an increase in blood cholesterol levels (triglycerides)
  • Precautions must be exercised if you have taken antidepressants like MAO inhibitors within the last 15 days
  • Dementia associated with bipolar disorder in elderly patients, who are at risk of stroke or transient ischemic attack
  • Co-Depricap 6mg+25mg Capsule 7 ‘S may alter heart rhythm(prolonged QT interval), which must be closely monitored especially if you have an existing heart condition. 
  • Hyperglycemia may occur, regular monitoring of blood sugar levels should be done
  • History of mania or seizures, risk of exacerbation exists
  • Uncontrolled movements can occur such as spontaneous lip puckering or smacking, consult a physician if you notice any abnormal bodily movements.
  • Raised intraocular pressure/ glaucoma
  • Renal impairment
  • Concomitant use with other antidepressants or anxiolytics 

Interaction with other medications

Certain medications could interact with Co-Depricap 6mg+25mg Capsule 7 ‘S, hence, in that case, your doctor might alter your dosage. A few of the interacting drugs are given below:

Please inform your doctor about the use of the following before taking Co-Depricap 6mg+25mg Capsule 7 ‘S:

  • MAO inhibitors (phenelzine, selegiline, tranylcypromine, etc.)
  • TCAs (amitriptyline, doxepin, imipramine, etc.)
  • Other SSRIs like sertraline 
  • Electroconvulsive Therapy (ECT)
  • Antipsychotics like pimozide 
  • Cimetidine 
  • Levodopa, dopamine agonists
  • CNS active drugs e.g., carbamazepine, diazepam, phenytoin
  • Clozapine 
  • Haloperidol 
  • Tryptophan 
  • Anti-clotting like Clopidogrel, warfarin
  • Alcohol 

Adverse effects

Like most medicines, Co-Depricap 6mg+25mg Capsule 7 ‘S has some side effects which include:

Common Side effects

  • Nausea 
  • Headache 
  • Fatigue 
  • Weakness
  • Insomnia or drowsiness 
  • Dizziness
  • Agitation 

Less Common Side effects

  • Hypersensitivity/allergic skin reactions 
  • Hallucinations 
  • Appetite changes 
  • Anxiety 
  • Dyspepsia/Flatulence
  • Sexual dysfunction
  • Erectile dysfunction in males
  • Nervousness
  • Attention-deficit
  • Palpitations
  • Paresthesia
  • Pruritis
  • Sweating
  • Tremors
  • Visual disturbances
  • Vomiting
  • Increased hostility
  • Weight gain
  • Hypertension
  • Movement disorders
  • Muscle twitching
  • Musculoskeletal pain (especially in limbs)
  • Photosensitivity
  • Cardiac arrhythmias 
  • Taste disturbances
  • Suicidal thoughts 
  • Neuroleptic malignant syndrome

HOW TO DEAL WITH SOME OF THE SIDE EFFECTS

  • Fatigue- Patients experiencing this adverse effect are advised to take deep breaths, intake tea or coffee, get a good night’s rest, and not overburden themselves for a few days.
  • Feeling drowsy – If the medication makes you feel drowsy or sleepy, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Headaches- In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
  • Feeling or being sick (nausea or vomiting) or diarrhea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. 
  • Feeling dizzy (lightheaded) or weak –If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Muscular Aches and Pains- A hot or cold compress can be placed at the area of discomfort to bring relief; an over-the-counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.
  • Constipation – Can be combated by adding more fibers to the patient’s diet, asking the patient to drink plenty of fluids, and increasing their physical activity to trigger contractions in the intestines.
  • Flatulence- This can be eased by consuming smaller, more frequent meals that don’t trigger your flatulence. Getting a minimum of 30 minutes of daily exercise has shown great results in combating flatulence. 
  • Heartburn – can be dealt with by chewing on mint-flavored gum that’ll help neutralize the acid in the body. Standing up straighter, adding ginger to the daily diet, elevating the patient’s upper body, and having licorice supplements has shown to provide relief.
  • Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
  • Change in taste- this tends to go away as soon as the patient stops taking the medicine but while treatment; saltwater with baking soda (half a teaspoon of salt and baking soda in water) rinses and chewing on sugar-free gum can help dissipate the change in taste.
  • Blurred vision- this side effect tends to go away on its own if a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.
  • Dehydration- Patients are recommended to always care around a water bottle with them wherever they go and periodically keep sipping to prevent thirst and extremely dry mouth. Ice pops in hot weather and energy drinks (verified by the doctor) help combat dehydration.
  • Soreness at the site of injection- a cold compress can be used for 5 minutes to ease out the soreness.
  • Dryness- apply a moisturizer to the skin and wait for 10-15 minutes after which apply Co-Depricap 6mg+25mg Capsule 7 ‘S onto the skin. This will prevent skin from getting dry and flaky.
  • Redness Of the Skin- This can be combated by applying a cold pack to the affected area.
  • Photosensitivity – patients are asked to wear sun-protective clothing when going outside including gloves and hats, to apply generous amounts of broad-spectrum sunblock along with wearing sunglasses. Patients are advised to do all necessary work after sunset to reduce or eliminate sun exposure while undergoing treatment with Co-Depricap 6mg+25mg Capsule 7 ‘S.

Key facts

  • Co-Depricap 6mg+25mg Capsule 7 ‘S is an antidepressant drug used to treat conditions including moderate to severe depression, eating disorders like bulimia nervosa, obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder.
  • Co-Depricap 6mg+25mg Capsule 7 ‘S is a chemical composition of Fluoxetine(Selective serotonin reuptake inhibitor (SSRI)) and olanzapine (antipsychotic)
  • Co-Depricap 6mg+25mg Capsule 7 ‘S can be prescribed to adults and children (10 years and above)
  • Co-Depricap 6mg+25mg Capsule 7 ‘S is to be taken orally in doses as prescribed by the doctor and must not be stopped abruptly to avoid withdrawal symptoms.
  • Extreme precaution is advised while taking this drug.
  • Normally takes 2-4 weeks for Co-Depricap 6mg+25mg Capsule 7 ‘S to show its effect
  • Consuming alcohol when taking Co-Depricap 6mg+25mg Capsule 7 ‘S may cause excessive drowsiness and could increase the risk of liver damage, hence should be avoided. 
  • Monitor your blood pressure and blood sugar levels regularly as it may cause an increase in levels.
  • Commonly Co-Depricap 6mg+25mg Capsule 7 ‘S is prescribed to patients with depression associated with bipolar disorder or those with a history of treatment resistance with other antidepressants
  • Common side effects of this medication are nausea, headache, dryness in the mouth, sleepiness, and dizziness

FAQs

#1. WHAT EXACTLY DOES Co-Depricap 6mg+25mg Capsule 7 ‘S DO?

It is an “antidepressant” (serotonin and noradrenaline reuptake inhibitor that works by increasing the levels of natural substances – chemical messengers (serotonin and noradrenaline), required to stop the movement of pain signals in the brain and to maintain mental balance.

#2. HOW LONG DOES IT TAKE FOR Co-Depricap 6mg+25mg Capsule 7 ‘S TO START WORKING?

Normally it takes 4-6 weeks for Co-Depricap 6mg+25mg Capsule 7 ‘S to show its effects.

#3. HOW LONG WILL I HAVE TO TAKE Co-Depricap 6mg+25mg Capsule 7 ‘S FOR?

Time duration depends on why you’re taking Co-Depricap 6mg+25mg Capsule 7 ‘S. For depression or anxiety, you will probably be asked to take it for a further 6 months or more after you start feeling better. Stopping it too soon might bring back your depression or anxiety. 

#4. CAN I STOP TAKING Co-Depricap 6mg+25mg Capsule 7 ‘S?

Do not just stop taking the medicine, make sure to complete your treatment course even if you feel better. Stopping it suddenly may cause withdrawal problems like difficulty sleeping, nausea, vomiting, sweating, and uncontrollable muscle movements. 

#5. IS Co-Depricap 6mg+25mg Capsule 7 ‘S HIGHLY ADDICTIVE?

No, as such it is not considered to be addictive, which means that it will not make you physically or psychologically dependent on it. However, stopping the medicine abruptly can cause undesirable withdrawal symptoms.

#6. DOES Co-Depricap 6mg+25mg Capsule 7 ‘S INTERFERE WITH WARFARIN? IS IT SAFE TO TAKE BOTH TOGETHER?

Taking both together could increase the risk of bleeding or you may experience petechiae or purpura.

#7. CAN I DRINK ALCOHOL WITH Co-Depricap 6mg+25mg Capsule 7 ‘S?

Consuming alcohol when taking Co-Depricap 6mg+25mg Capsule 7 ‘S may cause excessive drowsiness and could increase the risk of liver damage, hence should be avoided. 

#8. WHAT IF I TAKE TOO MUCH OF Co-Depricap 6mg+25mg Capsule 7 ‘S?

If you have taken too much of the prescribed Co-Depricap 6mg+25mg Capsule 7 ‘S you may experience symptoms of overdose for example, fast, pounding, or irregular heartbeat, upset stomach, blurred vision, fainting, dizziness, and seizures. Contact your doctor immediately if you have any of these symptoms. 

#9. WHAT IF I FORGET TO TAKE Co-Depricap 6mg+25mg Capsule 7 ‘S?

If you’re taking Co-Depricap 6mg+25mg Capsule 7 ‘S once a day then take the missed dose as soon as you remember, unless it’s less than 12 hours until your next dose, in which case you should skip the missed dose. If it helps to remind you, set an alarm so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

#10. CAN I TAKE Co-Depricap 6mg+25mg Capsule 7 ‘S DURING PREGNANCY OR BREASTFEEDING?

If you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor before using Co-Depricap 6mg+25mg Capsule 7 ‘S. If you are breastfeeding, please consult your doctor before taking Co-Depricap 6mg+25mg Capsule 7 ‘S. 

#11. CAN THE USE OF Co-Depricap 6mg+25mg Capsule 7 ‘S CAUSE DROWSINESS?

It may cause drowsiness, dizziness, fatigue (tiredness), and visual disturbances. However, it is uncommon and is not reported by many people. If you experience any of these symptoms avoid driving or operating heavy machinery.

#12. WILL Co-Depricap 6mg+25mg Capsule 7 ‘S AFFECT MY BLOOD PRESSURE?

Monitor your blood pressure regularly as it may cause an increase in blood pressure, especially during the first month of treatment. It can cause changes in heart rhythms depicted in ECG readings (prolonged QT interval).

#13. CAN I DRIVE OR RIDE A BIKE AFTER TAKING Co-Depricap 6mg+25mg Capsule 7 ‘S?

Make sure you know how your body reacts while using ‘product’ as it is known to make you feel dizzy. Do not drive or use any machinery until you feel normal again

#14. HOW SHOULD Co-Depricap 6mg+25mg Capsule 7 ‘S BE STORED?

Store it at room temperature, away from excess heat and moisture. Make sure it is not consumed by pets, children, and other people. Dispose of the unused medicine. 

#15. CAN Co-Depricap 6mg+25mg Capsule 7 ‘S AFFECT MY SEXUAL ACTIVITY?

Sexual dysfunction has been reported with Co-Depricap 6mg+25mg Capsule 7 ‘S. It may cause a decrease in libido. You must discuss this with your consultant.