Glempa Tablet 25mg 7 ‘S

Description

  • Glempa Tablet 25mg 7 ‘S is prescribed to treat type 2 diabetes
  • Glempa Tablet 25mg 7 ‘S contains Empagliflozin
  • Glempa Tablet 25mg 7 ‘S is to be taken orally (via mouth)
  • Glempa Tablet 25mg 7 ‘S is prescribed to adults and children
  • Glempa Tablet 25mg 7 ‘S is not to be ingested without a physician’s advice

 

Categories: ,
Type

Tablet

Feature

25mg

Unit

'S

Formula

Empagliflozin

Composition

Empagliflozin 25 mg

Brand

Nabiqasim Industries(Pvt) Ltd

Prescription Required

Yes

How to use, Side effects, Uses, Formula & Composition

Glempa Tablet 25mg 7 ‘S belongs to a class of drugs called “hypoglycemics” (anti-diabetics, sodium glucose co-transporter 2 (SGLT2) inhibitors) that are used in the treatment of type 2 diabetes 

  • When diet and exercise are inadequate in controlling blood sugar levels
  • As monotherapy (single drug treatment) if metformin is inappropriate, and
  • In combination with insulin or other antidiabetic drugs if the present condition is not suitably controlled.

Type 2 diabetes, also known as non insulin-dependent diabetes, is a condition resulting from a combination of insulin resistance, i.e, body cells failing to respond properly to the insulin produced, inadequate insulin secretion, and excessive production of glucagon. Progression of the disease may lead to insulin deficiency. This causes hyperglycemia. (high blood sugar levels)

This medicine is available in tablet form on prescription. It is prescribed to lower blood sugar levels by removing excess sugar from the body, through urine.

Dosage of Glempa Tablet 25mg 7 ‘S depends on age, severity of condition, patient’s response to medicine and their comorbidities.

Common side effects of this medication are frequent urge to urinate, pain or burning sensation while urinating, mild skin rash and thrush (oropharyngeal candidiasis – fungus growing in the mouth and throat)

Indications

Glempa Tablet 25mg 7 ‘S is prescribed to adults above 18 years of age but is not recommended for those above the age of 85.

It is used in the treatment of type 2 diabetes (high blood sugar levels) 

  • When diet and exercise are inadequate in controlling blood sugar levels
  • As monotherapy (single drug treatment) if metformin is inappropriate, and
  • In combination with insulin or other antidiabetic drugs if the present condition is not suitably controlled.

 

How does Glempa Tablet 25mg 7 ‘S work?

It is an anti-diabetic medication that works by increasing insulin (a natural substance required in breaking down sugar) production by the pancreas and the ability of the body to utilise it effectively.

 

How to use Glempa Tablet 25mg 7 ‘S?

Glempa Tablet 25mg 7 ‘S can be taken with or without meals, any time of the day as long as it’s around the same time everyday. 

Swallow the tablet whole with a glass of water. 

 

Dosage 

  • It is available in tablet form and the usual dose is 1 tablet per day
  • Recommended starting dose is usually 10mg/day which might be increased to 25mg/day if need be.
  • The dosage may vary if you’re taking it in combination with other medicines like metformin and linagliptin
  • Glempa Tablet 25mg 7 ‘S with Metformin (Synjardy)
    • Synjardy comes in 4 different strengths. Each tablet contains 5mg of Glempa Tablet 25mg 7 ‘S and either 850mg or 1g of Metformin. Appropriate strength will be prescribed to you by your doctor.
    • Usually 1 tablet is taken twice a day, with meals to prevent getting an upset stomach 
  • Glempa Tablet 25mg 7 ‘S with Linagliptin (Glyxambi)
    • Glyxambi comes in 2 different strengths. Each tablet contains 5mg of linagliptin and either 10 or 25mg of Glempa Tablet 25mg 7 ‘S. Appropriate strength will be prescribed to you by your doctor.
    • Usually 1 tablet is taken once a day, with meals to prevent getting an upset stomach

Pregnancy use and lactation

Use of Glempa Tablet 25mg 7 ‘S is not recommended in pregnancy or while breastfeeding. If you are pregnant, think you may be pregnant or are planning to have a baby, please consult your doctor before using Glempa Tablet 25mg 7 ‘S so that they can change your medicine. Usually it is not prescribed while breastfeeding as it could possibly affect the growth and development of the baby’s kidneys.

 

Contraindications

Please inform your doctor if you have a history of any before using Glempa Tablet 25mg 7 ‘S:

  • Type 1 diabetes mellitus (condition in which your body does not produce insulin) 
  • Elderly, 85 years and above
  • Allergic reaction (hypersensitivity) to the product or other medicines in the past
  • Severe liver disease
  • Severe kidney disease – eGFR (estimated glomerular filtration rate) <45mL/min/1.73msq
  • Heart problem
  • Breathing difficulties 
  • History of UTI (urinary tract infection)
  • About to have surgery
  • Alcoholism
  • Diabetic ketoacidosis (abnormally fast breakdown of fat into blood acids called ketones)

 

Precautions

Please tell your doctor about any of the following conditions while using Glempa Tablet 25mg 7 ‘S:

  • Pregnant, trying to get pregnant or breastfeeding
  • Elderly, above 75 years
  • Renal (kidney) impairment – kidney function needs to be monitored
  • Volume depletion – monitor volume status and electrolyte balance
  • Risk of diabetic ketoacidosis (abnormally fast breakdown of fat into blood acids called ketones) – test level of ketone bodies if symptoms occur
  • Pyelonephritis (inflammation of the kidney)
  • Urosepsis (body’s severe response to an infection of the urinary tract)
  • Glycosuria (abnormal presence of glucose in urine).
  • Cardiovascular (heart or its blood vessels related) diseases

 

Interaction with other medications

Certain medications could interact with Glempa Tablet 25mg 7 ‘S, hence, in that case your doctor might alter your dosage and make sure to monitor blood sugar levels more closely.

Please inform your doctor about the use of the following before taking Glempa Tablet 25mg 7 ‘S:

  • Diuretics (e.g furosemide)
  • Antihypertensives 
  • Antidepressants
  • Nitrates (for chest pain)
  • Baclofen (muscle relaxant)
  • Tamsulosin (for enlarged prostate)
  • Co-careldopa or levodopa (for parkinsons)
  • Agents that affect renal function
  • UGT enzyme inducers
  • Hypoglycemics (lower blood sugar) such as insulin and gliclazide – dosage will have to be decreased to avoid hypoglycemic events

 

Adverse effects

Like most medicines, Glempa Tablet 25mg 7 ‘S has some side effects which include:

Common:

  • Frequent urge to urinate
  • Pain or burning sensation while urinating
  • Mild skin rash
  • Thrush (oropharyngeal candidiasis – fungus growing in the mouth and throat)

Serious:

  • Hypoglycemia (low blood sugar) manifested as dizziness, weakness, drowsiness, headache and sweating
  • Anaphylaxis (allergic) reactions – difficulty breathing, swelling of your throat or tongue, hives, or difficulty swallowing
  • Diabetic ketoacidosis (abnormally fast breakdown of fat into blood acids called ketones) – indicated by nausea, vomiting, diarrhoea, excessive thirst, state of confusion or tiredness, stomach ache, fruity breath and rapid and deep breathing. 
  • Dehydration – characterised by dry mouth, excessive thirst, sleepy/tired, oliguria (decreased output of urine)
  • Urinary tract infection (UTI) – signs include high temperature, shivering, burning sensation while passing urine, pain in the back or side, hematuria (blood in urine)

 

How to cope with some of the adverse effects

  • Thrush – Apply an antifungal, if it persists even after a week, inform your doctor
  • Pain or burning sensation while urinating – This is usually a sign of UTI. Have plenty of fluids (it helps flushing out bacteria), have paracetamol (pain killer and rest. If it does not get better in 2-3 days, consult your doctor immediately 
  • Frequent urination – sign that you’re passing out more sugar in your urine. Contact your doctor if it is bothersome.
  • Mild skin rash – Take an antihistamine and inform your doctor if it does not go away. 
  • Hypoglycemia – Carry fast acting carbohydrates (like sweets and juice) to prevent your body from going into a state of hypoglycemia (low blood sugar)

Inform your doctor immediately if you experience any of the serious side effects.

 

Key facts about Glempa Tablet 25mg 7 ‘S

  • Glempa Tablet 25mg 7 ‘S is used for the treatment of type 2 diabetes mellitus (condition resulting in elevated levels of sugar in the blood) when diet and exercise are inadequate in controlling blood sugar levels, as monotherapy (single drug treatment) if metformin is inappropriate and In combination with insulin or other antidiabetic drugs if the present condition is not suitably controlled.
  • It is prescribed to adults above 18 but less than 85 years of age.
  • It works by increasing insulin (a natural substance required in breaking down sugar) production by the pancreas and the ability of the body to utilise it effectively.
  • It works on your kidneys by removing excess sugar from the body, through urine
  • When using Glempa Tablet 25mg 7 ‘S with other medicines it can cause hypoglycemia, (low blood sugar) hence, carry something sweet in case that happens.
  • Some people have shown to lose weight when taking Glempa Tablet 25mg 7 ‘S
  • Glempa Tablet 25mg 7 ‘S is best known to be taken with meals to prevent getting an upset stomach
  • Matter of concern arises when you experience constant dizziness, joint pain, cold-like symptoms, pain or burning sensation while urinating or unexplained nausea/vomiting. In that case contact your doctor immediately.
  • It is important for your doctor to monitor your blood sugar levels regularly, along with repeated tests to prevent you from any complications

FAQs

 

1. WHAT EXACTLY DOES Glempa Tablet 25mg 7 ‘S DO?

It is a sodium glucose co-transporter 2 (SGLT2) inhibitor that works by lowering blood sugar levels by removing excess sugar from the body, through urine.

2. HOW LONG DOES IT TAKE FOR Glempa Tablet 25mg 7 ‘S TO START WORKING?

It starts working almost immediately but might take upto a week to become fully effective. Initially, you might not feel that it is effective, but that does not mean you stop taking the medicine thinking it is not working. Make sure to continue taking Glempa Tablet 25mg 7 ‘S as directed by your doctor.

3. HOW LONG WILL I HAVE TO TAKE Glempa Tablet 25mg 7 ‘S FOR?

Glempa Tablet 25mg 7 ‘S is usually prescribed for long term use, possibly life long. Your dosage and time period is decided by your doctor after knowing the severity of your condition.

4. CAN I STOP TAKING Glempa Tablet 25mg 7 ‘S?

This medicine largely controls your blood sugar levels, but does not cure your condition. Hence, do not just stop taking the medicine without consulting your doctor, otherwise your condition could possibly get worse.

5. DOES Glempa Tablet 25mg 7 ‘S CAUSE WEIGHT GAIN OR WEIGHT LOSS?

Unlike most hypoglycemics it doesn’t cause weight gain but some individuals have shown to lose weight while taking Glempa Tablet 25mg 7 ‘S.

6. WHAT IF I TAKE TOO MUCH OF Glempa Tablet 25mg 7 ‘S?

An overdose of Glempa Tablet 25mg 7 ‘S can cause hypoglycemia (low blood sugar) indicated by feeling hungry, trembling or shaking, sweating, feeling confused and having problems concentrating. Contact your doctor immediately if you experience any of these signs.

7. WHAT IF I FORGET TO TAKE Glempa Tablet 25mg 7 ‘S?

Incase you miss a dose, take your next dose on time and do not try making up for the missed dose by doubling it up. If it helps to remind you, set an alarm so you do not miss any dose.

8. IS IT SAFE TO TAKE Glempa Tablet 25mg 7 ‘S WITH PAINKILLERS?

Yes, taking Glempa Tablet 25mg 7 ‘S with everyday painkillers like paracetamol and ibuprofen is safe.

9. CAN I DRINK ALCOHOL WHILE TAKING Glempa Tablet 25mg 7 ‘S?

Drinking alcohol in moderation is not harmful. However, alcohol intake increases the risk of hypoglycemia especially when you drink it on an empty stomach.

10. CAN I TAKE Glempa Tablet 25mg 7 ‘S BEFORE SURGERY ?

Inform your doctor that you are using Glempa Tablet 25mg 7 ‘S before surgery as he/she might ask you to stop taking the medicine before your operation. This is important as with the use of Glempa Tablet 25mg 7 ‘S there is a high risk of diabetic ketoacidosis (life threatening condition that occurs when blood glucose levels are too high)

11. CAN I DRIVE OR RIDE A BIKE AFTER TAKING Glempa Tablet 25mg 7 ‘S?

Glempa Tablet 25mg 7 ‘S alone might not affect your ability to drive or ride a bike, but when given in combination with other medicines, it could result in low blood sugar levels resulting in loss of concentration vision impairment (your eyesight is affected). To be on the safe side, always carry fast acting carbohydrates (like sweets and juice) to prevent your body from going into a state of hypoglycemia (low blood sugar)

12. HOW SHOULD Glempa Tablet 25mg 7 ‘S BE STORED?

Keep the medicine at room temperature in a cool, dry place, away from direct sunlight. Make sure to keep it away from pets, children and other people.