Lowplat 75mg Tablet 10 ‘S

Description

Lowplat 75mg Tablet 10 ‘S belongs to a class of drugs called “antithrombotic agents” used for prevention of heart attacks and strokes. It helps decrease the chances of having another heart attack or stroke in patients who have a history of a heart disease. 

It is an antiplatelet medicine or blood thinner that makes your blood flow through your veins easily. Moreover Lowplat 75mg Tablet 10 ‘S helps prevent the formation of blood clots in patients who have a high risk of having them. 

It is available on prescription, as tablets. Lowplat 75mg Tablet 10 ‘S works by decreasing the formation of blood clots by preventing platelets from sticking together. Thereby, lowering the chance of heart attack or stroke.

Common side effects of this medication are prolonged bleeding (you may have nosebleeds, heavier periods, bleeding gums or bruising) and upset stomach when taken with alcohol.

Dosage of Lowplat 75mg Tablet 10 ‘S depends on age, severity of condition, patient’s response to medicine and their comorbidities. It is not recommended for children below 18 years of age.

Indications

It can be used:

• For prevention of atherothrombotic events (formation of clots in arteries due to build-up of fats) in patients suffering from
• myocardial infarction – heart attack (from a few days until less than 35 days),
• ischaemic stroke – blood clot that blocks the vessel in the brain (from day 7 until less than 6 months) or 
• established peripheral artery disease (narrowed arteries reducing blood flow to limbs)
• In combination with aspirin in non-ST segment elevation in acute coronary syndrome; when heart muscle can not function properly or dies due to decreased blood flow in the arteries supplying it (unstable angina-chest pain or non-Q-Wave MI-heart attack).

How does Lowplat 75mg Tablet 10 ‘S work?

It is an antithrombotic agent used for prevention of heart attacks and strokes. It helps decrease the chances of having another heart attack or stroke in patients who have a history of a heart disease. Lowplat 75mg Tablet 10 ‘S works by decreasing the formation of blood clots by preventing platelets from sticking together. Thereby, lowering the chances of heart attack or stroke.

How to use Lowplat 75mg Tablet 10 ‘S?

• Lowplat 75mg Tablet 10 ‘S is available as tablets.
• Lowplat 75mg Tablet 10 ‘S is usually prescribed to be taken once a day around the same time every day, with or without food. 
• Take Lowplat 75mg Tablet 10 ‘S as prescribed by your doctor. 
• Do not chew or crush the tablet.
• To allow your body to adjust to the medication, your doctor will probably start you on a low dose of risperidone and then gradually increase it with time. 

Dosage

Form and Strength

Tablets

• 75mg
• 300mg

 

Usual dose is 75 mg daily with or without food.

Non-ST segment elevation acute coronary syndrome: 300 mg loading dose followed by 75 mg daily given in combination with 75-100 mg aspirin daily.

Doses are modified accordingly if a patient has renal or hepatic impairment.

Pregnancy use and lactation

If you are pregnant, think you may be pregnant or are planning to have a baby, please consult your doctor before using Lowplat 75mg Tablet 10 ‘S as it is contraindicated.

If you are breastfeeding, please consult your doctor before taking Lowplat 75mg Tablet 10 ‘S as it is contraindicated.

Contraindications

Please inform your doctor if you have a history of any before using Lowplat 75mg Tablet 10 ‘S:

• Allergic reaction to Lowplat 75mg Tablet 10 ‘S – indicated by skin rash, swelling around face area, wheezing, chest tightness and breathing difficulty
• Severe hepatic (liver) impairment
• Active bleeding such as peptic ulcer (stomach sore) or intracranial haemorrhage (brain bleed)
• Myocardial infarction (heart attack); do not initiate therapy within first few days
• PTCA (stenting)
• CABG (surgery improving blood flow to heart)
• Acute ischaemic stroke (blood clot in a vessel in the brain) of less than 7 days.

Precautions

Please tell your doctor about any of the following conditions while using Lowplat 75mg Tablet 10 ‘S:

• Elderly
• Renal impairment
• Hepatic impairment
• Surgery
• Risk of bleeding and blood dyscrasias (disorders); perform blood counts promptly if suspected and when used with other drugs or conditions that affect bleeding. Warn patients to report unusual bleeding
• Risk of acquired haemophilia (condition characterized by inability of blood to clot); discontinue if confirmed

Interaction with other medications

Certain medications could interact with Lowplat 75mg Tablet 10 ‘S, hence, in that case your doctor might alter your dosage and make sure to monitor blood sugar levels more closely.

Please inform your doctor about the use of the following before taking Lowplat 75mg Tablet 10 ‘S:

• Anticoagulants
• Glycoprotein IIb/IIIa inhibitors
• Thrombolytics
• NSAIDs
• SSRIs
• Pentoxifylline
• PPIs and other moderate or strong CYP2C19 inhibitors
• CYP2C8 substrates (e.g repaglinide).

Adverse effects

Like most medicines, Lowplat 75mg Tablet 10 ‘S has some side effects which include:

Common:

• prolonged bleeding (you may have nosebleeds, heavier periods, bleeding gums or bruising) 
• Diarrhoea
• Indigestion or heartburn
• Stomach ache

Serious:

• Hypersensitivity/allergic skin reactions; in this case discontinue 
• Bleeding episodes
• Gastrointestinal (stomach and bowel) disorder
• Haematoma (localized bleeding outside a blood vessel)
• Nervous system disorder
• hepatic (liver) impairment
• Biliary disorder 
• Haematological (blood-related) disorders
• Rarely, thrombotic thrombocytopenic purpura (rare blood disorder characterized by clotting in small blood vessels) and Stevens-Johnson syndrome (serious skin disorder of the skin or mucous membranes in reaction to medication).

How to cope with some of the adverse effects

• Bleeding more easily than normal – Be cautious of taking part in activities that could result in an injury or a deep cut. Always wear a helmet while cycling, gloves while using sharp objects like scissors and knives, use an electric razor instead of wet shaving, a soft toothbrush while brushing and a waxed dental floss. Contact your doctor if more than normal bleeding occurs. 

• Diarrhoea – Keep yourself hydrated by having lots of fluids and if the problem persists, consult your doctor before taking any medication for vomiting and diarrhoea

• Indigestion/heartburn – Avoid food items that cause wind. Try having smaller and more frequent meals.

• Stomach ache – Try to rest as much as possible and have smaller and more frequent meals. Using a heat pack or hot water bottle over the area in pain might help in giving some relief. If the pain still persists and is severe, speak to your doctor.

Inform your doctor immediately if you experience any of the serious side effects.

Key facts about Lowplat 75mg Tablet 10 ‘S

• {{product}} belongs to a class of drugs called  “antithrombotic agents” used for prevention of heart attacks and strokes. It helps decrease the chances of having another heart attack or stroke in patients who have a history of a heart disease. 
• It is an antiplatelet medicine or blood thinner that makes your blood flow through your veins easily. Moreover Lowplat 75mg Tablet 10 ‘S helps prevent the formation of blood clots in patients who have a high risk of having them. 
• It is prescribed to adults only. 
• Common side effects of this medication are prolonged bleeding (you may have nosebleeds, heavier periods, bleeding gums or bruising) and upset stomach when taken with alcohol.
• Your doctor may prescribe clopidogrel with or instead of low dose aspirin.
• Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you’re taking Lowplat 75mg Tablet 10 ‘S, unless advised by the doctor as it could increase the chance of bleeding.
• Matter of concern arises if you get a rash, itchy skin, swelling on the face and difficulty breathing, in which case you need to inform your doctor immediately. 
• Contact your doctor if:
• • you’re coughing up blood, or find blood in your urine, stool or vomit. 
  • Your skin or whites of the eyes turn yellow as it could be a sign of liver problem. 
  • You feel exhausted or have signs of an infection, such as a fever or sore throat; these could be a sign of a blood or bone marrow disorder

FAQs

 

1. WHAT EXACTLY DOES Lowplat 75mg Tablet 10 ‘S DO?

It is an antithrombotic agent used for prevention of heart attacks and strokes. It helps decrease the chances of having another heart attack or stroke in patients who have a history of a heart disease. Lowplat 75mg Tablet 10 ‘S works by decreasing the formation of blood clots by preventing platelets from sticking together. Thereby, lowering the chances of heart attack or stroke.

2. HOW LONG DOES IT TAKE FOR Lowplat 75mg Tablet 10 ‘S TO START WORKING?

It starts working within 2 hours of taking it. 

3. HOW LONG WILL I HAVE TO TAKE Lowplat 75mg Tablet 10 ‘S FOR?

The duration for using Lowplat 75mg Tablet 10 ‘S depends on the severity of your condition. It could be prescribed for a few weeks or months, or you may have to take it for lifetime.

4. CAN I STOP TAKING Lowplat 75mg Tablet 10 ‘S?

Do not just stop taking the medicine, make sure to complete your treatment course even if you feel better. Stopping it will result in the re-formation of blood clots at a rate at which they were before you started taking Lowplat 75mg Tablet 10 ‘S. As a result you will be at a higher risk of serious problems like heart attacks or strokes. 

5. CAN I DRINK ALCOHOL WITH Lowplat 75mg Tablet 10 ‘S?

Avoid consuming alcohol when taking Lowplat 75mg Tablet 10 ‘S to prevent the risk of stomach problems.

6. WHAT IF I TAKE TOO MUCH OF Lowplat 75mg Tablet 10 ‘S?

If you have accidentally taken 1 or 2 extra tablets, it is unlikely to harm you but the amount of Lowplat 75mg Tablet 10 ‘S that can lead to overdose varies from person to person. Hence, contact your doctor immediately if you have taken extra tablets and notice any sign of bleeding. 

7. WHAT IF I FORGET TO TAKE Lowplat 75mg Tablet 10 ‘S?

Incase you miss a dose, take your next dose on time and do not try making up for the missed dose by doubling it up. If it helps to remind you, set an alarm so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

8. CAN I TAKE Lowplat 75mg Tablet 10 ‘S DURING PREGNANCY OR BREASTFEEDING?

If you are pregnant, think you may be pregnant or are planning to have a baby, please consult your doctor before using Lowplat 75mg Tablet 10 ‘S as it is contraindicated.

If you are breastfeeding, please consult your doctor before taking Lowplat 75mg Tablet 10 ‘S as it is contraindicated.

9. HOW DOES Lowplat 75mg Tablet 10 ‘S COMPARE WITH OTHER ANTIPLATELET MEDICINES LIKE TICAGRELOR?

They both work to prevent blood clots and future heart attacks (if you have already had one) but the latter is not approved to prevent further strokes (if you have already had one). Lowplat 75mg Tablet 10 ‘S is usually taken once a day unlike ticagrelor which is taken twice a day and Lowplat 75mg Tablet 10 ‘S is known to cause less bleeding when compared to ticagrelor. 

10. IS THERE ANY FOOD OR DRINK I NEED TO AVOID WHILE TAKING Lowplat 75mg Tablet 10 ‘S?

Grapefruit juice may increase the blood-thinning effect of your medicine, hence it is advised not to drink it when taking Lowplat 75mg Tablet 10 ‘S. 

11. IS IT SAFE TO USE Lowplat 75mg Tablet 10 ‘S FOR A LONG TIME?

Lowplat 75mg Tablet 10 ‘S is generally safe to take for a long time. In fact, it works best if you take it for many months or even years. At times it may result in a stomach ulcer, but for that your doctor may prescribe a medicine to help prevent any ulcers from forming while taking Lowplat 75mg Tablet 10 ‘S.

12. WILL I HAVE TO STOP TAKING Lowplat 75mg Tablet 10 ‘S BEFORE SURGERY OR DENTAL TREATMENT?

Do not stop taking Lowplat 75mg Tablet 10 ‘S without consulting with your doctor or dentist. You will be informed if you need to stop taking it before any procedure. You might be advised to stop taking it for a short time before a procedure because of the risk of bleeding. 

13. DOES Lowplat 75mg Tablet 10 ‘S AFFECT BLOOD PRESSURE?

It may cause a decrease in blood pressure as a side effect. However, this is very rare and is not experienced by everyone. Consult your doctor if you feel dizzy, lightheaded, weak or have a blurred vision as these could be symptoms of low blood pressure. 

14. CAN I DRIVE OR RIDE A BIKE AFTER TAKING Lowplat 75mg Tablet 10 ‘S?

Lowplat 75mg Tablet 10 ‘S doesn’t affect your concentration, so you can drive or ride a bike while you’re taking it.

15. HOW SHOULD Lowplat 75mg Tablet 10 ‘S BE STORED?

Keep the medicine at room temperature in a cool, dry place, away from direct sunlight. Make sure it is not consumed by pets, children and other people. Dispose of the unused medicine when it is expired or no longer needed.