P-Sesq 40mg Tablet 14 ‘S

Description

About

P-Sesq 40mg Tablet 14 ‘S belongs to a group of drugs known as proton pump inhibitors. P-Sesq 40mg Tablet 14 ‘S is prescribed to treat the symptoms of Erosive Esophagitis associated with GERD (a syndrome in which the stomach’s acid flows backward, causing heartburn and possibly esophageal damage), GERD short-term therapy, and Zollinger-Ellison Syndrome (increased production of stomach acid due to malignancies in the pancreas and small intestine).

P-Sesq 40mg Tablet 14 ‘S is prescribed to adults and children at least 5 years old. P-Sesq 40mg Tablet 14 ‘S can be taken on its own or in combination with other drugs. 

P-Sesq 40mg Tablet 14 ‘S works by lowering the amount of acid produced by the stomach. It treats symptoms like heartburn, difficulties swallowing food, stomach pain, and vomiting by reducing excess acid production in the stomach. 

P-Sesq 40mg Tablet 14 ‘S is administered by trained medical professionals, as P-Sesq 40mg Tablet 14 ‘S is found in solution form to be administered intramuscularly or intravenously. It is usually given once a day for 7-10 days for the treatment of GERD and is given every 8-12hrs in conditions involving excess acid production. P-Sesq 40mg Tablet 14 ‘S is recommended only when oral administration of Pantoprazole is not recommended. 

If you have any significant side effects, such as symptoms of a low magnesium blood level (such as extremely fast/slow/irregular heartbeat, chronic muscle spasms, seizures), or evidence of lupus (such as rash on nose and cheeks, new or worsening joint pain), contact your doctor immediately. 

Indications

P-Sesq 40mg Tablet 14 ‘S is a prescription medicine used to treat the symptoms of:

• Erosive esophagitis (esophageal damage caused by stomach acid associated with Gastroesophageal reflux disease-GERD)
• Zollinger-Ellison syndrome
• Gastric and duodenal ulcers
• Other pathological hypersecretory conditions 

How Does P-Sesq 40mg Tablet 14 ‘S Work

P-Sesq 40mg Tablet 14 ‘S contains Pantoprazole as an active ingredient. P-Sesq 40mg Tablet 14 ‘S is a proton pump inhibitor (PPI) that covalently binds to the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell, suppressing the final step in stomach acid generation. Regardless of the stimulus, this action inhibits both basal and induced stomach acid output. For all doses studied, binding to the (H+, K+)-ATPase results in an antisecretory action that lasts longer than 24 hours (20 mg to 120 mg). 

How To Use P-Sesq 40mg Tablet 14 ‘S

A qualified healthcare practitioner injects P-Sesq 40mg Tablet 14 ‘S into the patient’s muscles (intramuscular route) or in the patient’s vein (intravenously). An alcohol swab or any other disinfectant available at the hospital is used to disinfect the area where the needle will pierce the skin. The needle is then unscrewed, and the solution is injected slowly into the body. P-Sesq 40mg Tablet 14 ‘S is infused intravenously nonstop for a period of time usually given once a day for 7-10 days for the treatment of GERD and is given every 8-12hrs in conditions involving excess acid production. 

A ready-to-use solution is prepared, within 12 hours of obtaining the solution, P-Sesq 40mg Tablet 14 ‘S must be administered. 

P-Sesq 40mg Tablet 14 ‘S should be given intravenously over for 2 to 15 minutes. 

The area of skin where the needle is inserted may bruise or be uncomfortable for up to 24 hours. The needle puncture is pressed down (by hand) for 20 seconds after the injection to ensure there is no bleeding, and then a band-aid is placed on top. It is not recommended that you use P-Sesq 40mg Tablet 14 ‘S with any other medications. P-Sesq 40mg Tablet 14 ‘S is usually given for up to 7days and up to 8 weeks at a time until your esophagus heals.

Dosage

Form and strength

Intravenous Infusion: 40mg

Adult Dosage 

Gastric and duodenal ulcers, and reflux esophagitis: the recommended adult dosage of P-Sesq 40mg Tablet 14 ‘S is one vial per day for 7-10days

Zollinger-Ellison syndrome and other pathological hypersecretory conditions: P-Sesq 40mg Tablet 14 ‘S can be given every 8-12hrs or as recommended by your doctor.

Child Dosage

Children’s experience is limited. As a result, until further data is available, P-Sesq 40mg Tablet 14 ‘S is not recommended for use in individuals under the age of 18. 

P-Sesq 40mg Tablet 14 ‘S is used in some cases to treat GERD in children who are at least 5 years old.

Elderly Dosage  

The elderly and individuals with a low body weight do not require any dosage adjustments. 

Pregnancy Use and Lactation

Because there is limited evidence on the use of P-Sesq 40mg Tablet 14 ‘S during pregnancy, as a precautionary measure it should only be used if a doctor has recommended it. 

P-Sesq 40mg Tablet 14 ‘S is a drug that can pass through breast milk. Avoid unless your doctor has recommended it. 

Contraindications

Before using P-Sesq 40mg Tablet 14 ‘S, consult your doctor if you have a medical history of any of the following:

• Allergic/hypersensitive to P-Sesq 40mg Tablet 14 ‘S and its contents
• If you are taking Rilpivirine for the treatment of HIV

Precautions

Please tell your doctor about any of the following conditions before using {{product}:

• Pregnancy and breast feeding
• Personal or family history of stomach cancer
• Avoid driving as you may feel dizzy and experience visual disturbances
• Avoid alcohol consumption as it may be associated with increased acid production
• P-Sesq 40mg Tablet 14 ‘S may worsen the symptoms if you have a history of systemic lupus erythematosus, contact your doctor if you experience any rash, painful joints, or lesions on the skin.
• P-Sesq 40mg Tablet 14 ‘S decreases your magnesium levels in the blood, contact your doctor if you experience dizziness, shivering, irregular heartbeat, muscle pain, seizures or shivering
• Long-term use of P-Sesq 40mg Tablet 14 ‘S can decrease absorption of Calcium in the body leading to thinning of bones, weak and brittle bones, and thus increased risk of bone fractures. It is advisable to consume Vitamin D and calcium supplements while using this medicine

Interactions With Other Medications

Consult your doctor about the use of the following medicines before using P-Sesq 40mg Tablet 14 ‘S:

• Neflinavinir
• Warfarin
• Digoxin 
• Methotrexate
• Atazanavir
• Ampicillin
• Medicines for fungal infections such as itraconazole and ketoconazole
• Iron salts

This document does not contain all probable drug reactions, it is advisable to keep a list of medicines in use and discuss it with your doctor (this includes prescription/nonprescription and herbal products). 

Adverse Effects

Rare Adverse Effects

Because P-Sesq 40mg Tablet 14 ‘S may induce serious and fatal infusion responses followed by cardiac collapse, the following side effects may require rapid attention and report to your doctor:

• Signs of allergic reaction such as itching, hives, swelling of face, lips and tongue, etc.
• Chest pain/tightness
• Breathing problems
• Bone, joint, or muscle pain
• Dark yellow/brown urine
• Stomach polyps 
• Fast or irregular heartbeat
• Dizziness
• Feeling fainted or lightheaded
• Muscle spasm
• Palpitations
• Fever and sore throat
• Rash on arms and cheeks that gets worse in the sun
• Tiredness
• Unusual signs of bleeding or bruising
• Yellowing of eyes or skin

Common Adverse Effects

Following side effects may not require immediate medical attention until becomes troublesome:

• Constipation
• Dry mouth
• Diarrhea
• Headache
• Nausea
• Pain or inflamation at injection site

How To Cope with Some of The Adverse Effects

• Feeling or being sick (nausea or vomiting) or diarrhea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water.
• Headaches- In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
• Feeling dizzy (lightheaded) or weak –If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Muscular Aches and Pains- A hot or cold compress can be placed at the area of discomfort to bring relief; an over-the-counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain
• Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Soreness at the site of injection- a cold compress can be used for 5 minutes to ease out the soreness.
• Dry Mouth- Can be helped by sipping water throughout the day, chewing sugarless gum and using alcohol-free mouthwash, allowing ice to melt in the mouth, or using a saliva substitute.
• Sore throat – Can be eased by adding honey to warm drinks and having oral lozenges, to provide soothing relief to an irritated throat. Ginger tea has been known to decrease inflammation of an irritated throat thus, providing relief.

FAQs

#1. How to store P-Sesq 40mg Tablet 14 ‘S?

Keep this drug out of children’s sight and reach. Do not use this drug after the expiration date, which is printed on the bottle and carton labels. Do not store below room temperature. 

Use as soon as possible after opening and/or dilution. This item is intended for one-time usage only. Any solution that has not been used should be discarded. 

Precipitation may form at chilly storage temperatures, but it will dissolve at normal temperatures. If you observe any visible particle matter or if the solution is hazy, do not use P-Sesq 40mg Tablet 14 ‘S

#2. What is P-Sesq 40mg Tablet 14 ‘S composed of?

P-Sesq 40mg Tablet 14 ‘S contains Pantoprazole as an active ingredient.

#3. What if I take too much of P-Sesq 40mg Tablet 14 ‘S?

If you’ve taken too much medicine, seek medical attention or call your doctor right away. 

#4. What if I miss a dose of P-Sesq 40mg Tablet 14 ‘S?

Contact your doctor for any missed dose.

#5. Will P-Sesq 40mg Tablet 14 ‘S affect my fertility??

Following some investigations, there was no evidence of diminished fertility concurrent the administration of P-Sesq 40mg Tablet 14 ‘S. 

#6. Can I take P-Sesq 40mg Tablet 14 ‘S during breastfeeding?

P-Sesq 40mg Tablet 14 ‘S is a drug that can pass through breast milk. Avoid unless your doctor has recommended it. 

#7. How long does P-Sesq 40mg Tablet 14 ‘S take to take effect?

Within 2-6 hours of dosing, P-Sesq 40mg Tablet 14 ‘S reaches its peak effect. 

#8. What is the duration of this medicine’s effects? 

The impact of P-Sesq 40mg Tablet 14 ‘S lasts for around 24 hours. 

#9. Is it okay to drink alcohol while taking P-Sesq 40mg Tablet 14 ‘S? 

Alcohol hasn’t been tested for interaction however it can be associated with increased acid production. Before consuming, it is essential to seek medical advice. 

#10. Is P-Sesq 40mg Tablet 14 ‘S a habit-forming medicine?

No, P-Sesq 40mg Tablet 14 ‘S has been found to have no addictive properties. 

#11. What lab tests will be prescribed while treatment with P-Sesq 40mg Tablet 14 ‘S?

Your doctor may prescribe you adjunct laboratory tests including magnesium levels in the blood at regular intervals.

#12. Why must I protect my skin from the sun while taking P-Sesq 40mg Tablet 14 ‘S?

Treatment with P-Sesq 40mg Tablet 14 ‘S may lead to the skin becoming sensitive to sun damage and it is therefore recommended to patients to always wear sunscreen, along with hats and gloves whenever possible to protect themselves from sun damage.

#13. Is it normal to feel lightheaded after getting injected with P-Sesq 40mg Tablet 14 ‘S?

 Yes, If P-Sesq 40mg Tablet 14 ‘S makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.

#14. What dietary instructions are to be followed when using P-Sesq 40mg Tablet 14 ‘S?

Continue to eat normally until your doctor tells you to switch to a specific diet.