Trusopt Eye 2% Drop 5 ml

Description

Overview

{{Product}} (Dorzolamide) is a topical medication prescribed for the treatment of glaucoma. Glaucoma is an eye ailment in which increased intraocular pressure (hypertension of the eye) causes the risk of visual impairment. So, the core purpose of prescribing this medication is to decrease the pressure in the eye.

How Does Trusopt Eye 2% Drop 5 ml Work

Carbonic anhydrase exists in an isoenzyme form in RBCs and other body tissues, including the eye where it plays a role in the secretion of aqueous humor. Its inhibition reduces the secretion of aqueous humor, reducing the intraocular pressure, and thereby treating glaucoma.

{{Product}} contains Dorzolamide as an active agent which acts as an effective inhibitor of this enzyme (carbonic anhydrase). The result is, reduced intraocular pressure which if remains elevated, can be a risk factor for optic nerve damage and loss of vision. {{Product}} works by reducing the secretion of aqueous humor rather than spasm or pupillary constriction. Therefore, it has no effects on blood pressure and does not show serious side effects like night blindness.

Dosing and Indications

{{Product}} is indicated in the following cases:

• As an adjunct to beta-blockers
• As monotherapy in patients for whom beta-blockers are not responsive or contraindicated
• Ocular hypertension (raised intra-ocular pressure)
• Open-angle glaucoma

Adult dose (Monotherapy)

1 drop three times a day

Adjunct therapy

1 drop two times a day

{{Product}} is not recommended for use in children

How To Use {{Product}}

Avoid touching the tip of the dropper to the fingers or any surfaces to minimize contamination. Administration may blur your vision for a few minutes. Keep the eyes closed for a few seconds to spread the medication entirely. The doses should be administered at regular intervals as prescribed and should not be used more often than directed.

Side Effects

Following are the possible side effects associated with the use of Trusopt Eye 2% Drop 5 ml:

• Temporary blurring of vision
• Itching and stinging sensation
• Tearing
• Headache
• Dizziness
• Crusting in the eyelids
• Transient Myopia (Nearsightedness)
• Corneal Oedema (Swelling of the cornea)

Precautions

• Known hypersensitivity to the active agent or Sulfur drugs
• Closed-angle glaucoma
• Any chronic condition of the cornea
• Hepatic impairment and kidney disease such as kidney stones
• Recent intraocular surgery
• Remove soft contact lenses before application and wear them back after 1t least 15 minutes of application.
• Do not blink at least after 30 seconds of application
• Instill another ophthalmic medication with a gap of at least 10 minutes

Contraindications

• Pregnancy and lactation
• Severe renal impairment 
• Hyperchloraemic acidosis (physiologic PH <7.35)
• Hypersensitivity to sulfur drugs

Interactions

• Oral carbonic anhydrase inhibitors (e.g., Dichlorphenamide)
• Topiramate
• Memantine

FAQs

Q. IS {{PRODUCT}} SAFE TO BE USED IN A PREGNANT WOMAN?

{{Product}} is not recommended for use in pregnant women due to the lack of safety data. Also, teratogenic effects have been observed in animal studies. However, the excretion of the active agent is unknown in breast milk.

Q. CAN {{PRODUCT}} CAUSE ANY SYSTEMIC ADVERSE EFFECTS?

The active agent, Dorzolamide in Trusopt Eye 2% Drop 5 ml is absorbed systemically therefore it renders additive effects of oral carbonic anhydrase inhibitors or in patients with a history of renal calculi. This is due to acid-base disturbances in vulnerable individuals.

Q. HOW {{PRODUCT}} IS USED AS AN ADJUNCTIVE TREATMENT?

Topical administration of beta-blockers (e.g., timolol) results in the reduction of intra-ocular pressure by a different mechanism of action. {{Product}} is prescribed topical beta-blockers as an adjunct when an additional reduction in the intraocular pressure is desired.

Q. WHAT WOULD HAPPEN IF I DON’T REMOVE CONTACT LENSES PRIOR APPLICATION OF {{PRODUCT}}?

The color of contact lenses is changed due to the absorption of Benzalkonium chloride by soft contact lenses and it can also lead to irritation and dryness of the eyes. Therefore, removal of contact lenses is advised 15 minutes before application.

Q. HOW DO I HAVE TO STORE {{PRODUCT}}?

Store at room temperature but not above 25°C. Don’t remove the secondary carton to protect the product from light. Avoid freezing.