Synalar-C 0.025%+3% Ointment 15 gm

Description

About

Synalar-C 0.025%+3% Ointment 15 gm belongs to a class of topical medicines which is a combination of synthetic steroids and antifungal medicine. Synalar-C 0.025%+3% Ointment 15 gm is prescribed for the treatment of several inflammatory skin conditions, suited for superficial skin conditions with an ongoing fungal infection or at risk of being infected, it also prevents and treats superimposed infections due to some bacterial strains. The skin conditions include Dermatitis, eczema, fungal nail infection, athlete’s foot, ringworm infections, open infected wounds, etc.

Synalar-C 0.025%+3% Ointment 15 gm contains Fluocinolone Acetonide, a powerful steroid, and Clioquinol, an antifungal belonging to the Quinoline class, which acts by reducing inflammation exhibited by swelling and redness, as well as possessing bacteriostatic properties against susceptible fungi and some bacteria. Some countries have shown concern over the side effects of Clioquinol and have banned it. It is therefore advised to discuss the safety concern with your doctor first.

Synalar-C 0.025%+3% Ointment 15 gm is available in the form of cream and ointment in a tube, meant for external use only. Synalar-C 0.025%+3% Ointment 15 gm can be applied in a thin coat over the affected area on the skin with clean hands, two to three times daily. Usually, clinical improvements can be seen in a few days and the treatment may last up to 2 weeks or less, as advised by your doctor. Do not use it for more than 2 weeks if there is no improvement. Common side effects of Synalar-C 0.025%+3% Ointment 15 gm include skin rash, itching, and skin dryness. 

Indications

Synalar-C 0.025%+3% Ointment 15 gm is prescribed for the management of a variety of skin conditions including:

• Dermatitis (contact/atopic)
• Infected dermatoses 
• Severe eczema 
• Psoriasis (non- plaque form)
• Infectious wounds/burns
• Fungal nail infection
• Ringworm  infection
• Other fungal infections of the skin

How Does Synalar-C 0.025%+3% Ointment 15 gm Work?

Synalar-C 0.025%+3% Ointment 15 gm is prescribed for inflammatory skin conditions with concurrent fungal infection. It works by acting on the skin via two basic mechanisms. Firstly, Fluocinolone being a corticosteroid controls the production of proteins that lead to inflammation by binding to Glucocorticoid receptors while also exerting vasoconstrictive action on blood vessels and controlling nitric oxide production, responsible for promoting inflammation. Also, it controls the infiltration and migration of inflammatory cells like leukocytes. It also inhibits Phospholipase A2 which speeds up the process of prostaglandin formation, a key mediator in inflammatory reactions. Synalar-C 0.025%+3% Ointment 15 gm thus decreasing the inflammation. Secondly, Clioquinol has antifungal and antiprotozoal action. The exact model of action for Clioquinol is not very clear yet, however its clinical effectiveness against yeast infection and bacteriostatic is well established.

How to use Synalar-C 0.025%+3% Ointment 15 gm?

Synalar-C 0.025%+3% Ointment 15 gm is available in the form of ointment and cream meant for external use only to be applied with clean hands usually two to three times daily after washing the affected skin properly and gently drying afterward. Synalar-C 0.025%+3% Ointment 15 gm is safe for use in adults and children above 2 years of age. Doctors must always be consulted first when using Synalar-C 0.025%+3% Ointment 15 gm in children, careful application and monitoring are thus advised to avoid accidental ingestion. Fluocinolone is a steroid, thus a prolonged application is not advised. 

Available Potency and forms of Synalar-C 0.025%+3% Ointment 15 gm 

Ointment – 15 g

Cream – 15 g

Usage

• Wash and gently pat dry your skin before applying the Synalar-C 0.025%+3% Ointment 15 gm. 
• Remove the cap by gently rotating it, break the top seal with the help of the pointed end given on the outer cap
• Take out a small amount of {{product} on fingertips and gently rub it in to form a thin, even coat over the affected area.
• Wash your hands after application, an additional amount can be reapplied if Synalar-C 0.025%+3% Ointment 15 gm gets wiped off from any part.
• {{product} is applied to the skin commonly three to four times a day for 7-10 days or as per the doctor’s suggestion

Dosage

Synalar-C 0.025%+3% Ointment 15 gm is not used for very long periods. Treatment is commonly prescribed for 7-10 days, if there’s no improvement in your symptoms after 7 days of application, consult your doctor who may consider changing the medicine for you. Dosage for the cream/ointment form can be estimated on the fingertips

Adult Dosage

A thin film of Synalar-C 0.025%+3% Ointment 15 gm is to be applied two to three times a day, or as instructed by a physician.

A small amount on the fingertips should be gently rubbed in. Application on the face is not advised for more than 5 days.

Child Dosage

Synalar-C 0.025%+3% Ointment 15 gm must not be used on children without consulting a doctor. It is not considered safe for application in patients aged 2 years and younger. Synalar-C 0.025%+3% Ointment 15 gm is not recommended for use for more than 7 days. Smaller amounts should be applied to a child’s body due to height and physique differences. Moreover, infants and children are likely to absorb more through the skin which can potentially result in side effects.

Only a pea-sized quantity on the fingertip is sufficient to cover the affected skin. Do not use Synalar-C 0.025%+3% Ointment 15 gm to treat diaper rash in infants.

Elderly Dosage 

For elderly patients the dosage of the drug may be lower than normal due to decreased kidney function, although Synalar-C 0.025%+3% Ointment 15 gm is absorbed through the skin in insignificant amounts but may pose a problem in elderly patients so, in such cases the doctor may prescribe an altered dose of the Synalar-C 0.025%+3% Ointment 15 gm.

Pregnancy use and lactation

Clioquinol contained in Synalar-C 0.025%+3% Ointment 15 gm is absorbed in greater amounts than other topical and should not be applied during pregnancy, therefore if you are pregnant, or are planning to start a family, please do discuss Synalar-C 0.025%+3% Ointment 15 gm with your doctor before using it, who will only prescribe if deemed necessary. In case you are a lactating mother, the full effects of Synalar-C 0.025%+3% Ointment 15 gm in breastfed infants are not yet known therefore if you are breastfeeding an infant, please make sure to consult your doctor first before using it.

 Contraindications

Please inform your doctor if you have a history of any before using Synalar-C 0.025%+3% Ointment 15 gm:

• Allergy to Synalar-C 0.025%+3% Ointment 15 gm or one of its constituents
• Skin lesions due to viral infection (for example herpes)
• Skin lesions due to Primary bacterial infection 
• Tuberculosis lesion on the skin
• Cushing’s disease
• Pregnancy 
• Glaucoma (especially avoid application near eyes)
• Diaper Rash
• Any skin condition likely to aggravate with  Synalar-C 0.025%+3% Ointment 15 gm such as acne
• Open wounds/ skin
• Raised intracranial pressure

Precautions‌ ‌

Please‌ ‌tell‌ ‌your‌ ‌doctor‌ ‌about‌ ‌any‌ ‌of‌ ‌the‌ ‌following‌ ‌conditions‌ before starting or during the treatment with ‌Synalar-C 0.025%+3% Ointment 15 gm:‌ 

• There has been a safety warning and eventual ban in some countries due to few reported cases of my-optic neuropathy with clioquinol, a component of ‌Synalar-C 0.025%+3% Ointment 15 gm. Discuss the safety risk with your doctor
• If there is a history of allergy to similar medicines such as other Quinolines or steroids
• Make sure to wash your hands thoroughly after application, to avoid getting ‌Synalar-C 0.025%+3% Ointment 15 gm in your eyes
• Do not use ‌Synalar-C 0.025%+3% Ointment 15 gm for long durations in continuity, if there is no noticeable difference in your condition after a week contact your doctor
• ‌Synalar-C 0.025%+3% Ointment 15 gm contains steroids which may put you at risk of infections or slow wound healing due to immunosuppression, if used for prolonged periods, take precautions accordingly 
• Diabetic patients or cases with borderline high blood sugar should be very careful while using Synalar-C 0.025%+3% Ointment 15 gm, monitor blood sugar regularly
• Avoid applying to open wounds or cracked skin except if advised by the doctor
• Fluocinolone in ‌Synalar-C 0.025%+3% Ointment 15 gm is a steroid that when used for a longer duration can cause suppression of adrenal gland function
• Avoid applying to sensitive parts like inside the nose, mouth or around the mouth, genitals, near eyes 
• Discuss with your doctor if you also have an existing thyroid condition
• Avoid going near fire or open flames to avoid risking burns
• Synalar-C 0.025%+3% Ointment 15 gm may initially cause exacerbation of existing symptoms or cause itching, redness, or irritation of the skin which should subside on its own
• Synalar-C 0.025%+3% Ointment 15 gm is best applied on naked skin without any bandages except if advised to cover it by your doctor
• As compared to other topical drugs Synalar-C 0.025%+3% Ointment 15 gm has shown greater absorption through the skin, do not apply more than prescribed time and quantity

Interaction with other medications

Topical medicines are minimally affected by interaction with other drugs. But some drugs may increase or decrease their absorption. Make sure to inform your doctor about all the drugs you’re currently taking, in which case, your doctor might alter the treatment. 

• Other skin medications (you can apply such drugs at different timings)
• Cosmetics (may decrease the efficacy, especially on the face)
• Skin products that might irritate the skin
• Vigabatrin (for seizures)

Adverse effects

Like most medicines, Synalar-C 0.025%+3% Ointment 15 gm has some side effects which include:

Common Side effects

• Itching/ pruritis
• Redness
• Dryness of skin 
• Flaky skin
• Tingling/ burning sensation at the site of application

Rare Side effects

• Anaphylactic reaction
• Headache 
• Blurred vision
• Pain in eyes 
• Dizziness 
• Blistering
• Temporary exacerbation of symptoms
• High intraocular pressure in eyes (if used in large amounts / near the eye)

List Of How to Deal with Adverse Effects

• Allergic Reactions – Allergic reactions to the drug may be mild to severe or potentially could be life-threatening. If allergy is suspected immediately take anti-allergy (antihistamine) medicine which will stop the mild reaction. If a serious allergic reaction is suspected rush to the nearby hospital and avoid Synalar-C 0.025%+3% Ointment 15 gm and drugs with similar compounds in the future.
• Skin Rash/ Blisters – can be eased by applying soothing and healing lotions or creams such as calamine or organic aloe vera lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Dryness – apply a moisturizer to the skin and wait for 10-15 minutes after which apply Synalar-C 0.025%+3% Ointment 15 gm onto the skin. This will prevent skin from getting dry and flaky.
• Headaches – In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
• Feeling or being sick (nausea or vomiting) or diarrhea – Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. 
• Feeling dizzy (lightheaded) or weak – If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Blurred vision- This side effect tends to go away on its own in a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.
• Photosensitivity – patients are asked to wear sun-protective clothes when going outside including gloves and a hat, to apply generous amounts of broad-spectrum sunblock along with wearing sunglasses. Patients are advised to do all necessary work after sunset to reduce or eliminate sun exposure while undergoing treatment with Synalar-C 0.025%+3% Ointment 15 gm.

FAQs

#1. How To Store Synalar-C 0.025%+3% Ointment 15 gm?

Synalar-C 0.025%+3% Ointment 15 gm is to be kept away from the reach of children and pets, in a cool dry place above 25°C,  away from direct sunlight and humidity as that tends to change the chemical nature of certain drugs.

#2. What If I Use Too Much Of Synalar-C 0.025%+3% Ointment 15 gm?

In case of excessive usage or accidental ingestion, kindly contact your doctor or nearby hospital right away. The amount of medication that can result in severe side effects varies from person to person. Toxicity results in slowing down of heart rate and difficulty breathing accompanied by dizziness and abdominal pain. 

#3. How Is Synalar-C 0.025%+3% Ointment 15 gm Supposed to Be Taken?

Synalar-C 0.025%+3% Ointment 15 gm  is available in ointment and cream form to be applied topically only over the affected area only.

#4. Can I Use Other Skincare Products Alongside Synalar-C 0.025%+3% Ointment 15 gm?

In case you want to use other skin creams or ointments, make sure these do not interact and use those products at a different time. Avoid applying make-up as well while using Synalar-C 0.025%+3% Ointment 15 gm.

#5. Can I Take Synalar-C 0.025%+3% Ointment 15 gm During My Pregnancy?

Synalar-C 0.025%+3% Ointment 15 gm should not be used in pregnancy due to unknown effects on the unborn baby. Consult your doctor regarding the safety of Synalar-C 0.025%+3% Ointment 15 gm first.

#6. Will Synalar-C 0.025%+3% Ointment 15 gm Affect My Fertility?

No, there isn’t sufficient evidence to suggest that patients experience a decrease in fertility.

#7. Can I Take Synalar-C 0.025%+3% Ointment 15 gm While Breastfeeding?

The full effects of Synalar-C 0.025%+3% Ointment 15 gm in breastfed infants are not yet known therefore if you are breastfeeding an infant, please make sure to consult your doctor first before using it. 

#8. Can Synalar-C 0.025%+3% Ointment 15 gm Cause Dizziness? If So, How Should I Manage It?

No, in general Synalar-C 0.025%+3% Ointment 15 gm does not cause dizziness but may occur as a rare side effect or may experience blurred vision. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during your treatment, as it may worsen the dizziness.

#9. How long Will I Have to Continue Taking  Synalar-C 0.025%+3% Ointment 15 gm?

It may be used twice or thrice a day. Treatment can last up to 7-10 days depending on your condition and response to the Synalar-C 0.025%+3% Ointment 15 gm. Treatment must not continue for longer periods in continuity, consult a doctor if there is no improvement in your condition after 1 week.

#10. Can I go Outside After Applying Synalar-C 0.025%+3% Ointment 15 gm?

Commonly Synalar-C 0.025%+3% Ointment 15 gm may be prescribed for application 2-3 times daily, you should avoid sun or UV exposure. Sensitivity to the sun may develop therefore If it is necessary to step outside make sure to protect your skin from direct sun or wear sunblock or clothes covering your skin.

#11. What if I accidentally get Synalar-C 0.025%+3% Ointment 15 gm in my eyes?

Careful application of Synalar-C 0.025%+3% Ointment 15 gm is necessary to avoid getting in your eyes because it can aggravate pre-existing glaucoma. If you accidentally get it in your eyes, thoroughly wash/rinse your eyes with cold tap water and immediately seek a doctor if necessary.