Dynaquin 500mg Injection 100 ml

Description

About

Dynaquin 500mg Injection 100 ml belongs to a class of drugs called “quinolone antibacterials” (fluoroquinolones). These are antibiotics that are used in the treatment of serious infections when other antibiotics fail to work. It is used to fight against bacterial infections and infections of the urinary tract, tonsils, sinus, nose, throat, female genital organ, skin and soft tissues, and lungs (pneumonia).

This medicine is available on prescription as an intravenous infusion to be administered into veins by a healthcare professional, commonly this is done in the hospital. Common side effects of this medication are nausea, diarrhea, headache, dizziness, and constipation. Dosage of Dynaquin 500mg Injection 100 ml depends on age, the severity of the condition, patient’s response to the medicine and their comorbidities.

Indications

Dynaquin 500mg Injection 100 ml is prescribed to adults and children above 1 year.

It is used in the treatment of:

• Infections caused by pathogens sensitive to levofloxacin
• Lower respiratory infection (infections in lungs or below the voicebox)
• Nosocomial pneumonia (hospital-acquired lung infection)
• Upper respiratory infection (infections above the voice box)
• Sinusitis (inflammation of the sinuses)
• Skin infection
• Urinary tract infection (UTI)
• Chronic bacterial prostatitis (swollen and inflamed prostate gland)
• Anthrax (serious infectious disease caused by gram-positive bacteria)
• Plague (serious bacterial infection).

How Does Dynaquin 500mg Injection 100 ml Work

It is an antibiotic that prevents bacterial cells from dividing and repairing. It works by inhibiting the action of a bacterial enzyme called DNA-gyrase, thereby, killing the bacteria. 

How To Use Dynaquin 500mg Injection 100 ml

The way you take your medicine depends on the type of Dynaquin 500mg Injection 100 ml and what you’re taking it for. It is available in form of oral tablets, syrup, and IV infusion vials. Follow the instructions that come with the medicine. Make sure to divide your doses evenly throughout the day. Make sure not to miss any dose and complete the full course of treatment. Dynaquin 500mg Injection 100 ml is available in liquid/injectable form, the anesthetic is administered into a patient’s vein (intravenously) by a trained healthcare professional or nurse as a slow IV infusion over a period of 60 minutes.

Dosage

Dosage is completely dependent on the age, the severity of the condition, the patient’s response to the medicine, and their comorbidities. Your doctor may vary your dosage to regulate your blood sugar levels.

Form and strength:

Premix, ready-to-use injection

• 250mg/50mL
• 500mg/100mL
• 750mg/150mL

Adults

• Lower respiratory infection: 

500 mg IV once daily for 7-14 days or 

750 mg IV once daily for 5 days.

• Nosocomial pneumonia: 

750 mg IV once daily for 7-14 days.

Community-acquired pneumonia:

500 mg IV twice daily 

• Upper respiratory infection- sinusitis: 

500 mg IV once daily for 10-14 days or

750 mg IV once daily for 5 days. 

• Skin infection: 

Uncomplicated: 500 mg IV once daily for 7-10 days

Complicated: 500 mg IV twice daily for 7-14 days.

• Urinary tract infection: 

Complicated UTI/Acute pyelonephritis: 250 mg IV once daily for 10 days. 

Uncomplicated UTI: 250 mg IV once daily for 3 days.

• Chronic bacterial prostatitis: 

500 mg IV once daily for 28 days.

• Anthrax (inhalational): 

500 mg IV once daily for 60 days, starting as soon as possible after exposure. 

• Plague (prophylaxis and treatment): 

500 mg IV once daily for 10-14 days, starting as soon as possible after exposure. 

A dose of 750 mg once daily may be considered if clinically warranted.

Children:

Anthrax (inhalational): 

Infants = 6 months and children = 50 kg: 8 mg/kg or IV twice daily for 60 days (do not exceed 250 mg/dose), beginning as soon as possible after exposure

Children >50 kg: 500 mg IV once daily for 60 days, beginning as soon as possible after exposure.

Plague (prophylaxis and treatment): 

Infants = 6 months and children = 50 kg: 8 mg/kg IV twice daily for 10-14 days (do not exceed 250 mg/dose), beginning as soon as possible after exposure

Children >50 kg: 500 mg IV once daily for 10-14 days, beginning as soon as possible after exposure. 

Pregnancy and Lactation

If you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor before using Dynaquin 500mg Injection 100 ml as it is contraindicated.

If you are breastfeeding, please consult your doctor before taking Dynaquin 500mg Injection 100 ml as it is contraindicated.

Contraindications

Please inform your doctor if you have a history of any before using Dynaquin 500mg Injection 100 ml:

• Allergic reaction to Dynaquin 500mg Injection 100 ml – indicated by skin rash, swelling around the face area, wheezing, chest tightness, and breathing difficulty
• Pregnancy and breastfeeding
• Tendon disorders
• Epilepsy (recurrent fits)
• Myasthenia gravis (an autoimmune disease characterized by muscle weakness and fatigue)
• MRSA infection (methicillin-resistant Staphylococcus aureus). 

Precautions

Please tell your doctor about any of the following conditions while using Dynaquin 500mg Injection 100 ml :

• Renal impairment (kidney damage)
• G6PD deficiency (genetic disorder mostly affecting males)
• Porphyria (rare inherited disorders)
• Risk of pseudomembranous colitis (inflamed large intestine) – discontinue if the patient has persistent diarrhea 
• History of tendon disorder (tendinitis – inflamed tendons)
• Diabetes (Dynaquin 500mg Injection 100 ml may affect blood sugar levels)
• Epilepsy (recurrent fits/seizures)
• History to CNS disorder – suffering from psychosis or a history of psychiatric disease
• Risk factors for QT prolongation (electrical disturbance in the heart)
• Avoid prolonged exposure to UV and refrain from driving or operating machinery. 

Interactions With Other Medications

Certain medications could interact with Dynaquin 500mg Injection 100 ml, hence, in that case, your doctor might alter your dosage and make sure to monitor blood sugar levels more closely.

Please inform your doctor about the use of the following before taking Dynaquin 500mg Injection 100 ml:

• Iron
• Antacids
• Sucralfate
• NSAIDs
• Fenbufen
• Probenecid
• Cimetidine
• Corticosteroids
• Vit K antagonists
• Drugs that prolong QT interval or lower seizure threshold
• Cyclosporin
• Theophylline

This document does not contain all probable drug reactions, it is advisable to keep a list of medicines in use and discuss it with your doctor ( this includes prescription/nonprescription and herbal products). 

Adverse Effects

Like most medicines, Dynaquin 500mg Injection 100 ml has some side effects which include:

Common Adverse Effects

Following side effects may not require immediate medical attention until becomes troublesome:

• Nausea 
• Indigestion (stomach ache)
• Diarrhea after taking tablets or liquid 
• Headache
• Dizziness 

Rare Adverse Effects

Side effects to report to your doctor or health care provider as soon as possible include: 

• Hypersensitivity/allergic skin reactions; in this case, discontinue 
• Raised liver enzymes
• Tendon disorders (discontinue use)
• Insomnia (inability to sleep)
• Anorexia (an eating disorder characterized by weight loss)
• Dysgeusia (distorted sense of taste)
• Dyspnoea (difficulty breathing)
• Arthralgia (joint pain)
• Myalgia (muscle pain)
• Tinnitus (ringing in ears)
• Asthenia (physical weakness)
• Pyrexia (fever)
• Visual disturbances
• Hepatic (liver) injury
• Severe skin disorders
• Peripheral neuropathy (damage to nerves outside the brain and spinal cord) – discontinue use 

How To Cope With Some Of The Adverse Effects

• Soreness at the site of injection- a cold compress can be used for 5 minutes to ease out the soreness.
• Headaches– In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe.
• Feeling dizzy (lightheaded) or weak -If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Flatulence- Can be eased by consuming smaller,more frequent meals that don’t trigger your flatulence.Getting a minimum of 30 minutes of daily exercise has shown great results in combating flatulence.
• Feeling or being sick (nausea or vomiting) or diarrhoea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. If you have diarrhea, replenish with plenty of water or other fluids. 
• Fatigue– Patients experiencing this adverse effect, are advised to take deep breaths,intake tea or coffee,get a good night’s rest and not to overburden themselves for a few days.
• Muscular Aches And Pains- A hot or cold compress can be placed at the area of discomfort to bring relief;an over the counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high intensity exercise while suffering from muscular pain.
• Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream.Apply a cold compress to the rash helps reduce itchiness and redness caused by rash.An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Blurred vision- This side effect tends to go away on its own if a few days;patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime.If blurred vision persists,please contact your doctor.

Key Facts About Dynaquin 500mg Injection 100 ml

• Dynaquin 500mg Injection 100 ml belongs to a class of drugs called “quinolone antibacterials” (fluoroquinolones). These are antibiotics that are used in the treatment of serious infections when other antibiotics fail to work
• It is prescribed to adults and children above 1 year.
• It is an antibiotic that prevents bacterial cells from dividing and repairing. It works by inhibiting the action of a bacterial enzyme called DNA-gyrase, thereby, killing the bacteria.
• Common side effects of this medication are nausea, indigestion (stomach ache), diarrhea, headache, and dizziness.
• Take Dynaquin 500mg Injection 100 ml at least 2 hours before or 2 hours after taking other products that may interact with it.
• Keep yourself hydrated when taking Dynaquin 500mg Injection 100 ml to prevent crystal formation in urine. 
• Matter of concern arises if you get a rash, itchy skin, swelling on the face,  difficulty breathing, pain in tendons, numbness or tingling sensation, in which case you need to inform your doctor immediately. 
• Use of Dynaquin 500mg Injection 100 ml is not recommended in pregnancy or while breastfeeding.

FAQs

#1. What exactly does Dynaquin 500mg Injection 100 ml do?

Dynaquin 500mg Injection 100 ml belongs to a class of drugs called “quinolone antibacterials” (fluoroquinolones) that prevent the bacterial cells from dividing and repairing. It works by inhibiting the action of a bacterial enzyme called DNA-gyrase, thereby, killing the bacteria.

#2. How long does it take for Dynaquin 500mg Injection 100 ml to start working?

For most infections, you will start feeling better in 2-3 days depending on the type of infection. Inform your doctor if you do not feel better or your condition starts to get worse.

#3. Can Dynaquin 500mg Injection 100 ml Increase the risk of muscle damage?

Yes, it is known to affect your muscles, commonly in the ankle (Achilles tendon). It can happen in patients of all ages, significantly more in patients above 60 years of age; inform your doctor if you feel any sort of muscle pain. 

#4. How long will I have to take Dynaquin 500mg Injection 100 ml for?

Dynaquin 500mg Injection 100 ml should be taken for as long as it is prescribed by your doctor. It is usually given for 1-2 weeks but it varies depending on the type of infection and its severity.

#5. Is there any food or drink I need to avoid?  

Avoid taking the tablets or liquid together with dairy products like milk, cheese, and yogurt because they prevent the Dynaquin 500mg Injection 100 ml from entering the body from the stomach. 

#6. When can I stop taking Dynaquin 500mg Injection 100 ml?

Do not just stop taking the medicine, make sure to complete your treatment course even if you feel better 

#7. Can I drink alcohol with Dynaquin 500mg Injection 100 ml?

It is safe to drink alcohol as there are no interactions that are known to occur.

#8. What if I take too much of Dynaquin 500mg Injection 100 ml?

If you have taken too much of the prescribed tablet or liquid form of dosage you may experience common side effects like nausea, vomiting, diarrhea, and an irregular heartbeat. 

#9. What if I forget to take Dynaquin 500mg Injection 100 ml?

In case you miss a dose, take your next dose on time and do not try making up for the missed dose by doubling it up. If it helps to remind you, set an alarm so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

#10. Can I take Dynaquin 500mg Injection 100 ml during pregnancy or breastfeeding?

Use of Dynaquin 500mg Injection 100 ml is not recommended in pregnancy or while breastfeeding. Please inform your doctor if you are pregnant, planning to conceive, or breastfeeding so that they can prescribe you a medicine accordingly without causing any complications for you or your baby.

#11. Is it safe to take Dynaquin 500mg Injection 100 ml for a long time?

It is usually prescribed for the short term. It has the potential to cause some serious long-term side effects like tendon rupture and hence should only be taken for the prescribed time duration and in cases where other antibacterials have failed to work.

#12. Can I drive or ride a bike after taking Dynaquin 500mg Injection 100 ml?

Make sure you know how your body reacts while using Dynaquin 500mg Injection 100 ml as it is known to make you feel dizzy, tired, and less alert. Do not drive or use any machinery until you feel normal again

#13. How should Dynaquin 500mg Injection 100 ml be stored? 

Keep this medicine tightly closed in the container or the pack it came in. Store it according to the instructions mentioned and dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people. Dynaquin 500mg Injection 100 ml is usually stored at temperatures between 15-30 degrees celsius in well-closed containers. Do not store it in moist or damp areas, such as the bathroom.