Refobacin 20mg Injection 1 ml

Description

About

Refobacin 20mg Injection 1 ml is used to treat serious bacterial infections that may not be responsive to other treatments. Refobacin 20mg Injection 1 ml belongs to a group of drugs known as aminoglycoside antibiotics that works by inhibiting the production of bacterial proteins thereby killing bacteria. 

Refobacin 20mg Injection 1 ml is available in injectable form and is given to the patient’s vein or muscle by a healthcare professional usually every 8hrs. The dosage of Refobacin 20mg Injection 1 ml is dependent upon the patient’s age, medical condition, patient’s response to the drug, any medications the patient might be having along with Refobacin 20mg Injection 1 ml and any adverse effects felt by the patient. Adjunct laboratory tests may be performed to help select the appropriate dosage (such as kidney function).

Refobacin 20mg Injection 1 ml is known to cause serious side effects such as damage to kidneys or hearing problems, so it is not recommended in newborn infants and elderly patients.

Indications

Refobacin 20mg Injection 1 ml can be used for:

• Bone infections
• Endocarditis
• Meningitis
• Pneumonia
• Urinary Tract Infections
• Pelvic inflammatory disease
• Sepsis

How Does Refobacin 20mg Injection 1 ml Work:

Refobacin 20mg Injection 1 ml belongs to a group of chemicals known as Aminoglycoside antibiotics. These drugs possess properties of both immediate and delayed bactericidal effects through membrane disruption and impaired protein synthesis. This works by inhibiting the production of bacterial proteins thereby killing bacteria.

How To Use Refobacin 20mg Injection 1 ml: 

Refobacin 20mg Injection 1 ml is available in liquid/injectable form, the anesthetic is administered into a patient’s vein (intravenously) or patient muscle (intramuscularly) by healthcare professionals and doctors usually every 8 hrs.

• Adjunct laboratory tests may be performed to help select the appropriate dosage (such as drug levels in blood and kidney function).
• Refobacin 20mg Injection 1 ml should be clear without any particulate matter or discoloration. 
• Make sure to divide your doses evenly throughout the day and at the same time each day.
• Make sure not to miss any dose and complete the full course of treatment.

Dosage

Form and strength 

• Injection: 10mg/1ml, 20mg/2ml, 40mg/1ml, 80mg/2ml, 160mg/2ml.

 For susceptible infections:

• Adult Dosage: 3-5mg/kg/day intravenously or intramuscularly every 8 hrs(Conventional dosing).

                                  4-7mg/kg/day IV every 24 hrs. (extended dosing interval).

• Pediatric Dosage: Children above 5yrs: 2-2.5mg/kg/dose IM/IV.

                                       Children below 5yrs: 2.5mg/kg/dose IV/IM every 8hrs.

• Infants: Under 30 weeks of gestation: 2.5-3 mg/kg/day IV/IM

                       Above 30 weeks of gestation: 3-5 mg/kg/day IV/IM           

Pregnancy and Lactation

Refobacin 20mg Injection 1 ml is not recommended to be prescribed to pregnant women until there is a life-threatening condition because it can harm the unborn baby. Use Refobacin 20mg Injection 1 ml with caution during breastfeeding as it is found in breast milk in trace amounts.                              

Contraindications

Please tell your doctor if you have a history of any of the following before using Refobacin 20mg Injection 1 ml:

1. Allergy to Refobacin 20mg Injection 1 ml or any other medicine (especially any antibiotic) or food substance.
2. Low levels of calcium, potassium, and magnesium in the blood (electrolytes imbalance)
3. Parkinson’s disease (movement disorder)
4. Myasthenia gravis (skeletal muscle disorder)
5. Hearing problems (decreased hearing, deafness)
6. Kidney problems
7. Pregnant women
8. Breastfeeding women

Precautions

Please tell your doctor about any of the following conditions before using Refobacin 20mg Injection 1 ml:

1. Elderly patients
2. Before a surgery (gentamicin can interact with other anesthetic agents and can cause serious side effects)
3. Do not take other medicines with Refobacin 20mg Injection 1 ml (includes prescription medicines, non-prescription medicines, vitamins, and herbal products).

Interactions With Other Medications

Please tell your doctor about the use of the following before using Refobacin 20mg Injection 1 ml:

1. Amikacin
2. Tobramycin
3. Amphotericin B
4. Cidofovir
5. Cisplatin
6. Polymyxin B
7. Cephalosporins (such as Cephaloridine)
8. Non-steroidal anti-inflammatory drugs NSAIDs (such as Ibuprofen)

Adverse Effects

Common Adverse Effects

1. Neurotoxicity (uncontrolled bodily movements, spinning sensation/vertigo)
2. Ototoxicity (Vestibular, auditory)
3. Kidney damage
4. swelling/ edema
5. Rash/itching
6. Injection site reactions (redness, irritation, pain)

Less common Adverse Effects

1. Increased salivation
2. Weight loss
3. Nausea, vomiting, stomach upset, loss of appetite
4. Burning, stinging
5. Tremors
6. Muscle cramps
7. Shortness of breath
8. Low platelets count (thrombocytopenia)

Serious Side Effects

1. Hearing loss
2. Ringing or roaring sounds in the ear
3. Reduced urinary output

How To Cope with Some of The Adverse Effects 

1. Muscular Aches and Pains- A hot or cold compress can be placed at the area of discomfort to bring relief; an over-the-counter pain reliever such as paracetamol or ibuprofen can be ingested to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.
2. Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
3. Dehydration- Patients are recommended to always carry around a water bottle with them wherever they go and periodically keep sipping to prevent thirst and extremely dry mouth. Ice pops in hot weather and energy drinks (verified by the doctor) help combat dehydration.
4. Soreness at the site of injection- a cold compress can be used for 5 minutes to ease out the soreness.
5. Feeling or being sick (nausea or vomiting) or diarrhea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. If you have diarrhea, replenish with plenty of water or other fluids. 

Key Facts About Refobacin 20mg Injection 1 ml

• Refobacin 20mg Injection 1 ml is an antibiotic 
• Refobacin 20mg Injection 1 ml is used to treat several bacterial infections
• Refobacin 20mg Injection 1 ml is safe to be prescribed to children.
• Refobacin 20mg Injection 1 ml is given to the patient’s vein or muscle by a healthcare professional usually every 8hrs.
• Continue using Refobacin 20mg Injection 1 ml until fully prescribed.

FAQs

#1. HOW DOES Refobacin 20mg Injection 1 ml WORK?

{product}} belongs to a widespread chemical group known as antibiotics. Refobacin 20mg Injection 1 ml works by preventing the growth/multiplication of the bacteria in the human body thus eradicating the infection. Refobacin 20mg Injection 1 ml essentially stops the production of bacterial cell walls, making the microorganism susceptible to elimination by the body’s defense system.

#2. HOW TO USE Refobacin 20mg Injection 1 ml?

Refobacin 20mg Injection 1 ml comes in a solution form that is injected into the muscle (intramuscularly) or vein (intravenously) by a health professional usually every 8hrs. When injected intravenously Refobacin 20mg Injection 1 ml is infused at a slower speed in a period of about 30mins to 2 hrs. once every 6-8 hrs.

#3. CAN Refobacin 20mg Injection 1 ml BE USED IF PATIENT IS HAVING FLU SYMPTOMS?

Refobacin 20mg Injection 1 ml is not deemed to be effective against viruses as Refobacin 20mg Injection 1 ml is an antibiotic and therefore works on bacteria to eliminate bacterial infections.

#4. HOW TO STORE Refobacin 20mg Injection 1 ml?

Refobacin 20mg Injection 1 ml is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.

#5. CAN I DRIVE AFTER TAKING THIS MEDICATION?

This medication is known to make you dizzy hence if that happens kindly avoid driving or operating any heavy machinery.

#6. WHAT DIETARY INSTRUCTIONS TO BE FOLLOWED WHEN USING Refobacin 20mg Injection 1 ml?

 Continue with the normal diet until you are instructed by your doctor to follow a special diet.

#7. WHAT IF I TAKE TOO MUCH OF Refobacin 20mg Injection 1 ml?

In case of overdose, kindly contact your doctor or nearby hospital right away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

#8. WHAT IF I MISS A DOSE OF Refobacin 20mg Injection 1 ml?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next dosage time or the next day, do not double the dose and take your medication as per schedule.            

#9. CAN I TAKE Refobacin 20mg Injection 1 ml DURING MY PREGNANCY?

No, Refobacin 20mg Injection 1 ml is deemed unsafe to be ingested during pregnancy until life-threatening conditions are present.

#10. WHAT LAB TESTS WILL BE PRESCRIBED WHILE TREATMENT WITH Refobacin 20mg Injection 1 ml?

Adjunct laboratory tests may be performed to help select the appropriate dosage (such as drug levels in blood and kidney function).

#11. IS IT SAFE TO HAVE PAINKILLERS WHILE TAKING Refobacin 20mg Injection 1 ml?

Yes. Over-the-counter painkillers such as paracetamol are safe to be ingested along with Refobacin 20mg Injection 1 ml under the supervision of a doctor.