Brine 500mg Injection 5 ml

Description

About

Brine 500mg Injection 5 ml belongs to a group of chemicals known as Antifibrinolytics, that aid in forming blood clots; therefore,Brine 500mg Injection 5 ml can be prescribed as a treatment for numerous illnesses varying from simple nose bleeds to hereditary angioedema a.Brine 500mg Injection 5 ml is also commonly prescribed to women facing heavy menstrual bleeding.

The drug comes packaged in an injection vial or an ampule, to be injected into a patient’s vein (intravenously) by a trained healthcare professional. The solution is injected slowly, as to not cause dizziness in a patient. The dosage can be divided into two or three separate doses, given within 24 hours, if need be, keeping a 6–8-hour gap between each dose.

Brine 500mg Injection 5 ml is versatile enough to be easily and safely, diluted/mixed with normal saline solution,5% glucose solution, Dextran solution as well as in Ringer’s lactate solution. Once mixed, the solution ought to be administered immediately; if there is a time lag of 12-24 hours the solution ought to be discarded. The prepared solution may be temporarily stored at 2-8 degrees Celsius.

Brine 500mg Injection 5 ml’s dosage and duration of treatment may differ for each patient, as the treatment regime for each patient depends upon their weight, stage of illness, each patient’s response to Brine 500mg Injection 5 ml and any pre-existing medical condition a patient might have. Brine 500mg Injection 5 ml may be prescribed to pregnant or lactating mothers or to women who are planning to start a family, after discussing the advantages and disadvantages at length with the patient.

Brine 500mg Injection 5 ml might show mild side effects such as fatigue, dizziness, and blurred vision which resolve on their own in a few days. Patients are asked to inform their physician if they’re ingesting other drugs especially if the patient is undergoing treatment with oral contraceptives or blood thinners as they have proved to interact negatively with Brine 500mg Injection 5 ml.

Indications

Brine 500mg Injection 5 ml can be used to treat:

• Prostatectomy 
• Bladder surgery 
• Nose bleeds
• Haematuria 
• Confiscation of the cervix
• Dental surgery 
• Bleeding disorders 
• Blood clotting diseases/disorders
• Leukaemia 
• Internal bleeding in the organs 
• Ulcerative colitis 
• Hereditary angioedema 
• Postpartum bleeding 
• Infants about to undergo cardiac surgery 
• Excessive blood loss due to trauma to the body

How Does Brine 500mg Injection 5 ml Work

Brine 500mg Injection 5 ml works by interfering with the degradation of fibrin (a protein structure that naturally helps form clots) and thereby preserving the fibrin matrix.

How To Use Brine 500mg Injection 5 ml

Brine 500mg Injection 5 ml is injected into the patient’s vein (intravenously) by a trained healthcare professional. The area where the needle is to pierce the skin is first disinfected with an alcohol swab or any other disinfectant that the hospital has. Then the needle was uncapped, and the solution was injected into the body. The solution is injected slowly, as to not cause dizziness in a patient. The dosage can be divided into two or three separate doses, given within 24 hours, if need be, keeping a 6–8-hour gap between each dose. The area of the skin where the needle enters may slightly bruise or remain sore for 24 hours. After the injection the needle prick is pressed down (by hand) for 20 seconds, to make sure there is no bleeding and then a band-aid is placed on top.

Brine 500mg Injection 5 ml is versatile enough to be easily and safely, diluted/mixed with normal saline solution,5% glucose solution, Dextran solution as well as in Ringer’s lactate solution.  Once mixed, the solution ought to be administered immediately; if there is a time lag of 12-24 hours, the solution ought to be discarded. The prepared solution may be temporarily stored at 2-8 degrees Celsius.

Dosage

Adult Dosage

An injection of 500mg is slowly infused at 3.75mg/kg/h into the human body if the drug is mixed with a solution. Brine 500mg Injection 5 ml is to be injected at the rate of 50mg/5ml, if 1 gram of drug is directly injected into the patient’s vein,

Adult Heart Surgery 

Before starting surgery, once the patient has been fully anesthetized,1 gram/kg of the drug is infused slowly into the patient. An additional dose of 4.5mg/Kg/h if need be.

Loading dose: 15 mg/kg

Followed By: Increments of 4.5mg/kg/h 

Additional dose: 0.6mg/kg/h if need be.

Adult Total Hip and Knee Arthroplasty

Before starting surgery, once the patient has been fully anesthetized,1 gram/kg of the drug is infused slowly into the patient. An additional dose of 15mg/Kg/h if need be.

Loading dose:15 mg/kg

Bolus dose (fast infused dose): 15 mg/kg, after 8 hours of the loading dose, if need be.

Child Dosage

For patients 

Aged 2 Years and Above:10mg/kg is initially administered. A dose of 10 mg/kg may be repeated if need be. Dosage may vary from patient to patient depending on everyone’s needs, age, and weight. The physician may alter the dosage accordingly.

Aged Below 2 Years of Age: There isn’t sufficient evidence to prove the safety or efficiency of Brine 500mg Injection 5 ml in this age group. Dosage may be altered especially if the patient has mild to moderate Kidney disease/impairment.

Physicians are advised to discuss all the advantages and disadvantages with the baby’s guardians at length, before administering any drug.

Elderly Dosage 

No change in dose is required for patients aged 65 years and above unless the patient is suffering from mild to moderate kidney disease/impairment.

Pregnancy Use and Lactation

Brine 500mg Injection 5 ml may be prescribed to expectant mothers only, when necessary, otherwise, the physician may prescribe an alternative drug to combat the same disease. Some studies show Brine 500mg Injection 5 ml having detrimental effects on the infant; therefore, before administering any drug, patients are advised to discuss the advantages and disadvantages of each drug at length with their physician.

Brine 500mg Injection 5 ml may pass to the infant via breastmilk but has not proved to have detrimental effects on the baby; patients are advised to consult a physician before starting treatment with any drug.

Contraindications

Please tell your doctor if you have a history of any of the following before using Brine 500mg Injection 5 ml:

• Allergic reaction to Brine 500mg Injection 5 ml or any other drug or ingredient
• Patients undergoing treatment for heat stroke 
• Moderate to severe kidney disease/impairment 
• Seizures 
• Coagulopathy 
• History of seizures 
• Deep vein thrombosis 
• Difficulty in viewing/differentiating colors 
• Brain hemorrhage 
• History of Brain hemorrhage
• Patients undergoing treatment for blood clots in the body 

Precautions 

Please tell your doctor if you have a history of any of the following before using Brine 500mg Injection 5 ml:

• Mild to moderate kidney disease/impairment
• Mild to moderate heart disease/impairment
• Irregular menstrual cycles 
• Certain types of birth control devices 
• Chain smokers 
• Easy bruising 

Interactions With Other Medications

Please tell your doctor about the use of the following before using Brine 500mg Injection 5 ml:

• Factor IX complex concentrates 
• Blood thinners 
• Certain oral contraceptives 
• NSAIDS 
• Estrogen hormone 
• Tretinoin
• Chlorpromazine 
• Medroxyprogesterone 

Adverse Effects

Common Adverse Effects

Like most medicines,Brine 500mg Injection 5 ml has certain side effects which include:

• Dizziness 
• Skin rash 
• Blurred vision 
• Headache 
• Stomach problems  (such as nausea, vomiting, and/or diarrhea)

These effects tend to be mild and resolve in a few days of taking Brine 500mg Injection 5 ml.

Rare Adverse Effects

If any of the following adverse effects are seen or felt, the patient is advised to immediately contact their doctor

• Difficulty in swallowing 
• Irritation/soreness at the site of injection
• Changes in perception of color
• Seizures 
• Extreme fatigue 

How To Cope with Some of The Adverse Effects

•  Headaches- In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
• Feeling or being sick (nausea or vomiting) or diarrhea –Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water.
• Feeling dizzy (lightheaded) or weak –If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
• Skin Rash- can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash helps reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Blurred vision – This side effect tends to go away on its own if a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.

FAQs

#1. Can I Take Brine 500mg Injection 5 ml During My Pregnancy?

There isn’t enough evidence to suggest that Brine 500mg Injection 5 ml is safe to be prescribed to expectant mothers, therefore, if you are pregnant or planning to start a family while undergoing treatment with Brine 500mg Injection 5 ml, it’s best to consult a physician before ingesting any drug

#2. How to Store Brine 500mg Injection 5 ml?

Brine 500mg Injection 5 ml is to be kept at temperatures of 2-8° Celsius. If Brine 500mg Injection 5 ml is mixed with other solutions; then it’s advised to dispose of the mixture after 24 hours.

#3. What Are Common Side Effects Caused By Brine 500mg Injection 5 ml?

• Dizziness 
• Stomach problems (such as nausea, vomiting, and/or diarrhea)
• Headache 
• Skin rash 
• Blurred vision

#4. Will Brine 500mg Injection 5 ml Affect My Fertility?

No, there isn’t sufficient evidence to suggest that patients experience a decrease in fertility.

#5. Is It Safe to Have Brine 500mg Injection 5 ml Along with Oral Contraceptives?

Not all oral contraceptives are safe to be taken while undergoing treatment with Brine 500mg Injection 5 ml as certain oral contraceptives (birth control pills) may negatively interact with Brine 500mg Injection 5 ml.

#6. Is It Normal to Feel Lightheaded After Getting Injected With Brine 500mg Injection 5 ml?

Yes, if Brine 500mg Injection 5 mlmakes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.

#7. Can Brine 500mg Injection 5 ml Be Administered to Infants?

Yes,Brine 500mg Injection 5 ml may be prescribed to patients aged 2 years and above. For patients aged 2 years and below, there isn’t sufficient evidence to prove the safety of Brine 500mg Injection 5 ml; the drug may be administered after discussing the advantages and disadvantages at length with the guardians of the patient.

#8. What Is Brine 500mg Injection 5 ml Composed Off?

Brine 500mg Injection 5 ml is composed of Tranexamic acid.

#9. Is Brine 500mg Injection 5 ml Safe to Give to Elderly Patients?

Yes. This drug can be easily and safely prescribed to patients above 18 years of age. For elderly patients, the dosage of the drug may be lower than normal due to decreased kidney function.

#10. Can I Drive After Taking This Medication?

This medication is known to make you dizzy hence if that happens kindly avoid driving or operating any heavy machinery.