Moduretic 5mg+50mg Tablet 10 ‘S

Moduretic 5mg+50mg Tablet 10 ‘S is prescribed to treat high blood pressure (hypertension) and heart failure

Moduretic 5mg+50mg Tablet 10 ‘S is also commonly prescribed to reduce fluid (water) retention in the body 

Moduretic 5mg+50mg Tablet 10 ‘S contains Hydrochlorothiazide and Amiloride

Moduretic 5mg+50mg Tablet 10 ‘S is to be taken orally (via mouth)

Moduretic 5mg+50mg Tablet 10 ‘S is to be ingested under doctor’s advisement 

Moduretic 5mg+50mg Tablet 10 ‘S is safe to be prescribed to adults (aged 18 years and above)

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Description

Moduretic 5mg+50mg Tablet  is most commonly prescribed for the treatment of high blood pressure (hypertension), heart attacks, and kidney problems. Moduretic Tablet performs the function of lowering high blood pressure. Furthermore, it also helps prevent strokes and is also recommended during the treatment of edema, and water retention which may occur in patients with congestive heart failure. Moduretic Tablet belongs to the category of potassium-sparing diuretics, also known as water pills. 

Moduretic Tablet is most commonly recommended to patients who have such low levels of potassium that it starts to become dangerous for them, Moduretic Tablet helps the unneeded water and salt in the body to flush down from the kidney through urine. Patients might also be required to adapt to a few lifestyle changes along with the consumption of the medication as it would help control blood pressure and bring about a healthy diet. 

Moduretic Tablet should not be taken without consultation of a doctor if the patient has any liver diseases, kidney diseases, diabetes, is pregnant, or plans on getting pregnant. Some common adverse effects might occur during the consumption of medicine such as thirst, rash, respiratory disease, tremors, nausea, insomnia, dizziness, and a few more. 

Indications 

Moduretic Tablet can be used to treat: 

  • Hypertension 
  • Congestive heart failure 
  • Oedema and ascites in cirrhosis of the liver 
  • Kidney problem

How To Use Moduretic Tablet

Moduretic 5mg+50mg Tablet 10 ‘S is to be ingested orally with water to help the tablet flow down the throat easily. It can be consumed with or without food and should not be chewed or crushed. Moduretic 5mg+50mg Tablet 10 ‘S should be ingested only as directed by the medical expert. The medicine should be consumed daily if instructed by the doctor, if another medicine is recommended along with Moduretic 5mg+50mg Tablet 10 ‘S by the doctor then it should not be forgotten and ingested accordingly as many times as directed by the doctor.

How Does Moduretic Tablet Work 

Moduretic 5mg+50mg Tablet 10 ‘S contains both elements which help the patients with low levels of potassium which might be harmful to them. Moduretic Tablet helps the excessive and unwanted water and salt in the body to pass out of the body through urine. This further helps in reducing the quantity of fluid flowing through the blood resulting in lowered blood pressure. 

Dosage 

Adult Dosage 

  • Hypertension: Initially 2.5/25mg daily which could be increased to 5/50mg daily.
  • Congestive Heart Failure:  Initially 2.5/25mg daily which could be increased to 10/100mg daily and reduced dose for maintenance if needed.
  • Oedema and Ascites in cirrhosis of the liver: Initially 5/50mg daily which could be increased to 10/100mg, reduce dose for maintenance if needed.

Not recommended for children.

Pregnancy Use And Lactation

Medicine has shown potential risks and can be harmful to the fetus hence should be avoided during pregnancy. If a patient gets pregnant during the administration then she should consult his doctor. 

Moduretic Tablet is advised to not be administered to the nursing mother as it may be exerted into the breastmilk and cause infant harm. There has been no potential evidence of harm but there are potential risks therefore Moduretic Tablet is advised to be avoided. It is unsure whether Amiloride does get excreted into breast milk but hydrochlorothiazide does get excreted, hence if it is consumed by a nursing mother it should be done so in small doses. 

Precautions 

The doctor should be informed about the following conditions before using Moduretic 5mg+50mg Tablet 10 ‘S:

  • Diabetes 
  • Acidosis 
  • Gout 
  • renal/hepatic impairment 
  • Hyperaldosteronism 
  • Malnourishment 
  • Nephrotic syndrome 
  • Systemic lupus erythematosus 
  • Hypokalemia 

Contraindications 

The doctor should be informed about the following/history of any of these before using Moduretic Tablet:

  • Addison’s disease 
  • Anuria 
  • Hypercalcaemia 
  • Hyponatraemia 
  • Refractory hypokalemia 
  • Symptomatic hyperuricemia 
  • Unable to urinate 
  • Glaucoma 
  • High level of cholesterol 
  • Breathing disorder 

Interactions With Other Medicines

  • K+ supplement 
  • K+ sparing diuretics 
  • Digitalis 
  • Lithium 
  • Antihypertensives 
  • ACE inhibitors 
  • Tacrolimus 
  • Blood pressure medications 

Adverse Effects 

Common effects 

  • Nausea 
  • Dizziness 
  • upset stomach
  • diarrhea
  • loss of appetite
  • stomach pain
  • gas
  • Headache
  • Restlessness 
  • Sexual dysfunction 
  • Thirst
  • Rash 
  • Dry mouth

Rare side effects 

  • slow or irregular heartbeat
  • unusual bleeding or bruising
  • yellowing of the skin or eyes
  • hives
  • itching
  • difficulty breathing or swallowing
  • Fever 
  • Jaundice 
  • Respiratory disturbances 
  • Ocular pressure 
  • Tinnitus 
  • Visual disturbances 
  • Malaise 
  • Dyspnea 
  • Angina 
  • urinary disturbances

How To Cope With Some Adverse Effects 

Headaches- In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe

Nausea or Diarrhea -Avoid eating rich or spicy food. It might help to take medication after food. If you are sick, try drinking small, frequent sips of water.

Feeling dizzy-If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.

Skin Rash- Can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash helps reduce itchiness and redness caused by the rash. An antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.

Fever- Patients are asked to ingest over-the-counter painkillers (such as Paracetamol), partake in plenty of fluids, and rest for a couple of days till the symptoms pass. 

Dry Mouth – Can be helped by sipping water throughout the day, chewing sugarless gum, using alcohol-free mouthwash, allowing ice to melt in the mouth, or using a saliva substitute.

FAQ’s

Q1.HOW TO STORE Moduretic 5mg+50mg Tablet 10 ‘S?

Moduretic 5mg+50mg Tablet 10 ‘S is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.

Q2. WHAT IF I TAKE TOO MUCH OF Moduretic 5mg+50mg Tablet 10 ‘S?

An extra dose or two of Moduretic 5mg+50mg Tablet 10 ‘S is not known to cause any harm but excess ingestion of Moduretic 5mg+50mg Tablet 10 ‘S is a cause for concern and should be avoided and immediately reported to the doctor

Q3.WHAT IF I MISS A DOSE OF Moduretic 5mg+50mg Tablet 10 ‘S?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next dosage time or the next day, do not double the dose and take your medication as per schedule.

Q4.HOW IS Moduretic 5mg+50mg Tablet 10 ‘S SUPPOSED TO BE TAKEN?

Moduretic 5mg+50mg Tablet 10 ‘S is to be ingested orally with water to help the tablet flow down the throat easily. It can be consumed with or without food

Q5.WILL Moduretic 5mg+50mg Tablet 10 ‘S AFFECT MY SEXUAL ACTIVITY?

Yes. As Moduretic 5mg+50mg Tablet 10 ‘S may lead to difficulty in maintaining an erection or cause a painful erection.

Q6. Can I Take Moduretic 5mg+50mg Tablet 10 ‘S During My Pregnancy?

No,Moduretic 5mg+50mg Tablet 10 ‘S is not advised to be ingested during pregnancy.

Q7. CAN Moduretic 5mg+50mg Tablet 10 ‘S CAUSE DIZZINESS? IF SO, HOW SHOULD I MANAGE IT?

Yes. It can cause dizziness as one of the most common side effects. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during your treatment, as it may worsen the dizziness.

Q8. DOES Moduretic 5mg+50mg Tablet 10 ‘S CAUSE ADDICTION?

No. This drug has shown no evidence to prove addiction of any kind in any patient.

 

 

 

 

Additional information

Feature

5mg+50mg

Unit

'S

Formula

Amiloride

Composition

Amiloride 5 mg + Hydrochlorothiazide 50 mg

Brand

OBS Pharma

Prescription Required

Yes