Amodip Plus 5mg/12.5mg Tablet 20 ‘S
Description
About
Amodip Plus 5mg/12.5mg Tablet 20 ‘S has two main chemical groups that work harmoniously together to bring about low levels of blood pressure in patients who suffer from high blood pressure regularly Amodip Plus 5mg/12.5mg Tablet 20 ‘S combines two separate drug groups into one very efficient tablet. One of the chemical groups is known as Calcium Channel Blockers; this chemical group prevents the narrowing of blood vessels, therefore, easing the flow of blood to the various body organs and easing the flow of blood in the blood vessels themselves. This action coupled with a diuretic (Hydrochlorothiazide) that causes a decrease of excessive fluid in the body (increased amount of urine is produced and excreted by patients taking this drug) efficiently lowers raised levels of blood pressure (hypertension).
Hypertension left untreated can cause severe damage to the brain, heart, kidney, blood vessels, and other body organs. Amodip Plus 5mg/12.5mg Tablet 20 ‘S is prescribed when a single chemical group alone is not able to efficiently treat high blood pressure thus this drug is known as the second line of treatment for hypertension, therefore Amodip Plus 5mg/12.5mg Tablet 20 ‘S dosage is determined by the patient’s stage of illness and their response to treatment with this drug.
It is advised that Amodip Plus 5mg/12.5mg Tablet 20 ‘S should be taken a minimum of 4-5 hours before sleeping at night as it may cause disrupted sleep due to the need to urinate at night time. Amodip Plus 5mg/12.5mg Tablet 20 ‘S is not recommended for expecting or lactating mothers as it causes damage to the fetus. Women planning on starting a family should refer to their doctor, the doctor is likely to change the dosage of the drug, depending on the patient’s health. If the patient is in taking medicines to combat high cholesterol along with Amodip Plus 5mg/12.5mg Tablet 20 ‘S then the physician may ask these patients to have their cholesterol medication 4-6 hours before ingesting Amodip Plus 5mg/12.5mg Tablet 20 ‘S.
One tablet daily is the usual prescribed dose Amodip Plus 5mg/12.5mg Tablet 20 ‘S is to be taken regularly, preferably at the same time each day to help the patient remember their daily dose. The patient ought to discuss this with their physician before ceasing intake of the medicine even if the patient is no longer suffering from common symptoms of hypertension as ceasing the intake of the medicine has been reported in cases of rebound hypertension (the re-emergence of high blood pressure), therefore, physicians taper of the product’s dosage before completely stopping it.
Indications
Amodip Plus 5mg/12.5mg Tablet 20 ‘S can be used to treat:
- Hypertension
How Does Amodip Plus 5mg/12.5mg Tablet 20 ‘S Work
Two things that increase blood pressure levels from the normal (120/80mmHg) range are increased amounts of fluid in the body that leads to a higher than normal amount of blood flowing through vessels that aren’t built to withstand such high amounts of fluid daily. Excessive fluid together with narrowed blood vessels (decrease in diameter) cause Hypertension.
Amodip Plus 5mg/12.5mg Tablet 20 ‘S works by preventing both the unnecessary retention of fluid in the body and the narrowing of blood vessels and therefore, allowing normal amounts of blood flow and easy access of blood to the various organs and easing the flow of blood within the vessel itself.
Amodip Plus 5mg/12.5mg Tablet 20 ‘S can bring about the desired effect by the perfect and unique combination of two chemical groups known as Calcium Channel Blockers (prevent a decrease in blood vessel diameter by blocking the entry of Calcium ions) and Diuretics (prevent fluid retention in the body by allowing excess fluid to be lost via urine).
How To Use Amodip Plus 5mg/12.5mg Tablet 20 ‘S
A tablet a day is most commonly prescribed to patients to be taken either with or without food.
Please note that any alcohol consumption is to be reported to the doctor while undergoing treatment with Amodip Plus 5mg/12.5mg Tablet 20 ‘S as alcohol tends to make the patient dizzy and feel faint. It is advised that Amodip Plus 5mg/12.5mg Tablet 20 ‘S should be taken a minimum of 4-5 hours before sleeping at night as it may cause disrupted sleep due to the need to urinate at night time. If patients find it difficult to swallow the tablet whole, they can break/slice it in half and ingest the tablet in two separate pieces but at the same time.
Ingesting cholesterol-lowering medication along with Amodip Plus 5mg/12.5mg Tablet 20 ‘S decreases its effectiveness and therefore, it is advised that patients use their cholesterol medicine 4-6 hours before having Amodip Plus 5mg/12.5mg Tablet 20 ‘S. It is advised to not stop treatment abruptly without consulting a doctor as the risk of heart failure and stroke is significantly increased without the drug. If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next day, do not double the dose and take your medication as per schedule, leading to serious adverse effects. If this happens very often, try setting an alarm as a reminder.
Dosage
Adult Dosage
One tablet is prescribed to be taken every day, at the beginning of the treatment. The dose of Amodip Plus 5mg/12.5mg Tablet 20 ‘S may be altered after a two-week grace period depending upon the patient’s reaction to the drug.
Child Dosage
For patients under the age of 18 years, Amodip Plus 5mg/12.5mg Tablet 20 ‘S is not considered safe and is therefore not prescribed.
Elderly Dosage
For patients under the age of 65 years, due to decreased kidney function, Amodip Plus 5mg/12.5mg Tablet 20 ‘S may not be effectively removed from the body and so, in such cases the doctor may prescribe a lower dose of the Amodip Plus 5mg/12.5mg Tablet 20 ‘S.
Pregnancy Use And Lactation
This drug is not to be taken or prescribed to expecting and lactating mothers as it may have fatal consequences for the unborn child. If you are taking the drug and become pregnant, inform your doctor immediately. Small amounts of this drug can be transferred to the child through breast milk and therefore cause low blood pressure in the child thus this Amodip Plus 5mg/12.5mg Tablet 20 ‘S isn’t recommended to lactating mothers. If you are planning to conceive and are taking Amodip Plus 5mg/12.5mg Tablet 20 ‘S as treatment, then refer to the doctor. The physician is likely to change your medicine and dosage.
Contraindications
Please tell your doctor if you have a history of any of the following before using Amodip Plus 5mg/12.5mg Tablet 20 ‘S:
- Allergic reaction to Amodip Plus 5mg/12.5mg Tablet 20 ‘S or any other drug or ingredient
- Biliary cirrhosis (scarring)
- Cholestasis (reduced bile flow from the liver)
- Severe hepatic impairment (liver damage)
- Moderate to severe Kidney disease/impairment
- Moderate to severe Heart disease/impairment
- Mineral imbalance (increased/decreased levels of potassium, magnesium, and calcium)
- Dehydration
- Gout
- Cancer (especially skin cancer)
- Autoimmune disorder (especially lupus)
Precautions
Please tell your doctor if you have a history of any of the following before using Amodip Plus 5mg/12.5mg Tablet 20 ‘S:
- Mild to moderate hepatic (liver) impairment
- Biliary obstruction (blockage of bile ducts)
- Salt or volume depletion
- Aortic or mitral stenosis (heart valve narrowing)
- Malignant hyperthermia (severe reaction to certain drugs used for anesthesia)
- Hypertensive crisis (severe increase in blood pressure)
- Moderate to severe renal (kidney) impairment
- Renal artery stenosis (narrowing of blood vessels in the kidney)
- Heart failure or post-MI (heart attack)
- Old age
- Diabetes
- Primary hyperaldosteronism (excessive aldosterone production)
Interactions With Other Medications
Please tell your doctor about the use of the following before using Amodip Plus 5mg/12.5mg Tablet 20 ‘S:
- Fibrates (cholesterol controlling medicine)
- Cyclosporine (an immunosuppressant drug)
- Cholestyramine (cholesterol controlling medicine)
- Colestipol (cholesterol controlling medicine)
- Azole antifungals (used to prevent diseases caused by various fungi)
- Niacin (Vitamin B3)
- Drugs metabolized by cytochrome P450 3A4,
- Digoxin (used to treat certain heart conditions such as atrial fibrillation)
- Erythromycin (an antibiotic used to treat bacterial infections)
- Oral contraceptives
- Antacids (used to treat heartburn, indigestion, and other stomach ailments)
- Warfarin (anticoagulant)
- Lithium
Adverse Effects
Common Adverse Effects
Like most medicines, Amodip Plus 5mg/12.5mg Tablet 20 ‘S has certain side effects which include:
- Muscle cramps
- Dizziness
- Dehydration
- Fatigue
- Stomach pain (nausea, diarrhea, vomiting)
- Headaches
These effects tend to be mild and resolve in a few days of taking Amodip Plus 5mg/12.5mg Tablet 20 ‘S.
Rare Adverse Effects
If any of the following adverse effects are seen or felt, the patient is advised to immediately contact their doctor
- Hypotension
- Blurred vision
- Extreme thirst
- Sleep disturbances
How To Cope With Some Of The Adverse Effects
- Feeling dizzy (lightheaded) or weak -If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
- Feeling or being sick (nausea or vomiting) or diarrhea -Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. If you have diarrhea, replenish with plenty of water or other fluids.
- Headaches– In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe.
- Dehydration– Patients are recommended to always care around a water bottle with them wherever they go and periodically keep sipping to prevent thirst and extremely dry mouth. Ice pops in hot weather and energy drinks (verified by the doctor) help combat dehydration.
- Fatigue- Patients experiencing this adverse effect, are advised to take deep breaths, intake tea or coffee, get a good night’s rest, and not overburden themselves for a few days.
FAQ’s
#1. Can Lifestyle Changes Help Me With My Condition?
Yes. you can adopt certain healthy lifestyle changes to help with high blood pressure. These include quitting smoking, avoiding alcohol, eating a wholesome diet consisting of fresh vegetables and fruits with the cut down on salt, and incorporating physical activity into your daily routine.
#2. What If I Take Too Much Of Amodip Plus 5mg/12.5mg Tablet 20 ‘S?
In case of too much consumption by accident, kindly contact your doctor or nearby hospital straight away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.
#3. Is It Safe To Have Amodip Plus 5mg/12.5mg Tablet 20 ‘S Before Undergoing Any Surgical Procedure?
If the surgical procedure involves general anesthesia, the surgeon may ask the patient to stop their intake of the drug for 24 hours as general anesthesia also tends to lower blood pressure levels in a few patients.
#4. How Is Amodip Plus 5mg/12.5mg Tablet 20 ‘S Supposed To Be Taken?
Amodip Plus 5mg/12.5mg Tablet 20 ‘S is to be ingested orally one to two times daily or as per the doctor’s prescription. Amodip Plus 5mg/12.5mg Tablet 20 ‘S is to be taken either with or without food, preferably with water to ease the tablet’s passage to the patient’s throat.
#5. How Does Amodip Plus 5mg/12.5mg Tablet 20 ‘S Work?
Amodip Plus 5mg/12.5mg Tablet 20 ‘S can bring raised blood pressure levels by combining two chemical groups; Calcium Channel Blockers (prevent a decrease in blood vessel diameter by blocking the entry of Calcium ions) and Diuretics (prevent fluid retention in the body by allowing excess fluid to be lost via urine).
#6. Can I Take Amodip Plus 5mg/12.5mg Tablet 20 ‘S During My Pregnancy?
No. Amodip Plus 5mg/12.5mg Tablet 20 ‘S has been known to cause harm to the fetus and cause complications during pregnancy. Hence, it is advised to consult your doctor if you are pregnant or planning to become pregnant or may think you are pregnant. Small amounts of this drug can be transferred to the child through breast milk and therefore cause low blood pressure in the child thus Amodip Plus 5mg/12.5mg Tablet 20 ‘S isn’t recommended to lactating mothers. If you are planning to conceive and are taking Amodip Plus 5mg/12.5mg Tablet 20 ‘S as treatment, then refer to the doctor. The physician is likely to change your medicine and dosage.
#7. How To Store Amodip Plus 5mg/12.5mg Tablet 20 ‘S?
Amodip Plus 5mg/12.5mg Tablet 20 ‘S is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.
#8. Does Amodip Plus 5mg/12.5mg Tablet 20 ‘S Cause Addiction?
No. This drug has shown no evidence to prove addiction of any kind in any patient.
#9. What Lab Tests Will Be Prescribed While Treatment With Amodip Plus 5mg/12.5mg Tablet 20 ‘S And How Often?
Kidney and liver function tests along with blood tests to keep a check on serum potassium levels are advised to be done periodically. It is also advised that patients learn to monitor their blood pressure levels daily from the comfort of their homes and inform their doctor of any changes seen.
#10. Can I Consume Alcohol With Amodip Plus 5mg/12.5mg Tablet 20 ‘S?
Alcohol is also known to lower your blood pressure which if taken with the medication may lead to extreme dizziness. It is best to avoid the intake of alcohol during your treatment.
#11. How Long Will I Have To Continue Taking The Medication?
It is a long-term treatment and you might have to continue taking the medication even for the rest of your life
#12. What If I Forget To Take The Amodip Plus 5mg/12.5mg Tablet 20 ‘S?
It is advised that the drug is taken at the same time each day, an alarm can be placed to remind patients to take Amodip Plus 5mg/12.5mg Tablet 20 ‘S at the proper time and at least an hour before having any meal. If the patient misses a dose of Amodip Plus 5mg/12.5mg Tablet 20 ‘S, they should take it immediately but if the time for the next dose of the drug is near then it’s beneficial for patients to skip the missed dose and take the tablets as per schedule, doubling of doses has proven to cause severe side effects.
#13. Is Amodip Plus 5mg/12.5mg Tablet 20 ‘S Safe To Give To Elderly Patients?
Yes. This drug can be easily and safely prescribed to patients above 18 years of age. For elderly patients the dosage of the drug may be lower than normal due to decreased kidney function, Amodip Plus 5mg/12.5mg Tablet 20 ‘S may not be effectively removed from the body and so, in such cases, the doctor may prescribe an altered dose of the Amodip Plus 5mg/12.5mg Tablet 20 ‘S.
#14. Can Amodip Plus 5mg/12.5mg Tablet 20 ‘S Interfere With Fertility?
There is no evidence to support the above statement. If a patient does become pregnant it is imperative that they inform their doctor immediately as Amodip Plus 5mg/12.5mg Tablet 20 ‘S can have fatal effects on the developing fetus.
#15. What Are Common Side Effects Caused By Amodip Plus 5mg/12.5mg Tablet 20 ‘S?
- Muscle cramps
- Dizziness
- Dehydration
- Fatigue
- Stomach pain (nausea, diarrhea, vomiting)
- Headaches
#16. Can I Drive After Taking This Medication?
This medication is known to make you dizzy hence if that happens kindly avoid driving or operating any heavy machinery.
Additional information
| Type | Tablet |
|---|---|
| Feature | 5mg/12.5mg |
| Unit | 'S |
| Formula | Amlodipine |
| Composition | Amlodipine 5 mg + Hydrochlorothiazide 12.5 mg |
| Brand | Mass Pharma (Pvt) Ltd |
| Prescription Required | Yes |

