Co-Aprovel 300mg+25mg Tablet 14 ‘S

Co-Aprovel 300mg+25mg Tablet 14 ‘S is prescribed for the treatment of hypertension (high blood pressure)

Co-Aprovel 300mg+25mg Tablet 14 ‘S contains irbesartan (angiotensin receptor blocker) and hydrochlorothiazide (a diuretics)

Co-Aprovel 300mg+25mg Tablet 14 ‘S is to be taken orally (via mouth)

Co-Aprovel 300mg+25mg Tablet 14 ‘S is prescribed to adults only 

 

Description

About

Co-Aprovel 300mg+25mg Tablet 14 ‘S has two main chemical groups that work harmoniously together to bring about low levels of blood pressure in patients who suffer through high blood pressure on a regular basis.Co-Aprovel 300mg+25mg Tablet 14 ‘S combines two separate drug groups in one very efficient tablet.One of the chemical groups is known as Angiotensin II Receptor Blockers;this chemical group prevents the narrowing of blood vessels therefore easing the flow of blood to the various body organs and easing the flow of blood in the blood vessels themselves.This action coupled with a diuretic that causes a decrease of fluid in the body (increased amount of urine is produced and excreted by patients taking this drug) efficiently lowers raised levels of blood pressure (hypertension).

Hypertension left untreated can cause severe damage to the brain, heart, kidney,blood vessels and other body organs.Co-Aprovel 300mg+25mg Tablet 14 ‘S is prescribed when a single chemical group alone is not able to efficiently treat high blood pressure thus this drug is known as a second line of treatment for hypertension,therefore,Co-Aprovel 300mg+25mg Tablet 14 ‘S dosage is determined by the patient’s stage of illness and their response to treatment with this drug.

It is advised that Co-Aprovel 300mg+25mg Tablet 14 ‘S should be taken a minimum of 4-5 hours before sleeping at night as it may cause disrupted sleep due to the need to urinate at night time.Co-Aprovel 300mg+25mg Tablet 14 ‘S is not recommended to expecting or lactating mother as it causes damage to the fetus.Women planning on starting a family should refer to their doctor,the doctor is likely to change the dosage or the drug depending of the patient’s health.If patient is intaking medicines for combat high cholesterol along with Co-Aprovel 300mg+25mg Tablet 14 ‘S then the physician may ask these patients to have their cholesterol medication 4-6 hours prior to Co-Aprovel 300mg+25mg Tablet 14 ‘S.

One tablet daily is the usual prescribed dose.Co-Aprovel 300mg+25mg Tablet 14 ‘S is to be taken regularly,preferably at the same time each day to help the patient remember their daily dose.The patient ought to discuss with their physician before ceasing intake of the medicine even if the patient is no longer suffering from common symptoms of the hypertension as ceasing the intake of the medicine has reported in cases of rebound hypertension (the re-emergence of high blood pressure),therefore, physicians taper of the Co-Aprovel 300mg+25mg Tablet 14 ‘S’s dosage before completely stopping it.

Indications

Co-Aprovel 300mg+25mg Tablet 14 ‘S can be used to treat

  • High Blood Pressure (Hypertension) 

How Does Co-Aprovel 300mg+25mg Tablet 14 ‘S Work

Two things that increase blood pressure levels from the normal (120/80mmHg) range are increased amounts of fluid in the body that leads to a higher than normal amount of blood flowing through vessels that aren’t built to withstand such high amounts of fluid on a daily basis.

Excessive fluid together with narrowed blood vessels (decrease in diameter) cause Hypertension. Co-Aprovel 300mg+25mg Tablet 14 ‘S works by preventing both the unnecessary retention of fluid in the body and the narrowing of blood vessels and therefore,allowing normal amounts of blood flow and easy access of blood to the various organs and easing the flow of blood within the vessel itself.

 Co-Aprovel 300mg+25mg Tablet 14 ‘S is able to bring about the desired effect by the perfect and unique combination of two chemical groups known as Angiotensin II Receptor Blockers (prevent decrease in blood vessel diameter by blocking angiotensin,a natural hormone found in the human body that works by narrowing blood vessels) and Diuretics (prevent fluid retention in the body by allowing excessive  fluid to be lost via urine).

How To Use Co-Aprovel 300mg+25mg Tablet 14 ‘S

A tablet a day is most commonly prescribed to patients to be taken either with or without food.

Please note that any and all alcohol consumption is to be reported to the doctor while undergoing treatment with Co-Aprovel 300mg+25mg Tablet 14 ‘S as alcohol tends to make the patient dizzy and to feel faint.It is advised that Co-Aprovel 300mg+25mg Tablet 14 ‘S should be taken a minimum of 4-5 hours before sleeping at night as it may cause disrupted sleep due to the need to urinate at night time.If patients find it difficult to swallow the tablet whole,they can break/slice it in half and ingest the tablet in two separate pieces but at the same time.

It is advised to not stop treatment abruptly without consulting a doctor as the risk of heart failure and stroke is significantly increased without the drug.If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next day, do not double the dose and take your medication as per schedule as that will lead to serious adverse effects. If this happens very often, try setting an alarm as a reminder.

Dosage

Adult Dosage  

One tablet is to be ingested per day by adults between the ages of 18-65.

Child Dosage

Co-Aprovel 300mg+25mg Tablet 14 ‘S is for adult use only and is therefore not prescribed to individuals under the age of 18 years.

Elderly Dosage

For elderly patients above the age 65 years or for patients suffering from mild to moderate kidney impairment,the dosage may be lowered.Co-Aprovel 300mg+25mg Tablet 14 ‘S is not prescribed to patients suffering from severe kidney impairment.

Pregnancy Use And Lactation

This drug is not to be taken or prescribed to expecting and lactating mothers as it may have fatal consequences for the unborn child.If you are taking the drug and become pregnant,inform your doctor immediately,the doctor will ask you to stop using Co-Aprovel 300mg+25mg Tablet 14 ‘S and is likely to replace it with a different pregnancy safe drug.Small amounts of this drug can be transferred to the child through breast milk and therefore cause low blood pressure in the child thus Co-Aprovel 300mg+25mg Tablet 14 ‘S isn’t recommended to lactating mothers.If you are planning to conceive and are taking losartan as treatment, then refer to the doctor.The physician is likely to change your medicine and dosage.

Contraindications

Please tell your doctor if you have a history of any of the following before using Co-Aprovel 300mg+25mg Tablet 14 ‘S:

  • Allergic to Co-Aprovel 300mg+25mg Tablet 14 ‘S or any medication or food substance
  • Kidney impairment 
  • Dehydration (loss of fluids and minerals due to excessive sweating,diarrhea or vomiting)
  • Gout (excessive amount of uric acid in the body)
  • Lupus (an autoimmune disorder)
  • Cancer (especially skin cancer)
  • Cholestasis (decreased bile flow)
  • Pregnancy
  • Mineral imbalance (increased/decreased levels of potassium,magnesium and calcium)
  • Severe hepatic impairment (liver damage)
  • Heart condition
  • Diabetes mellitus
  • Glaucoma

Precautions

Please tell your doctor about any of the following conditions before using Co-Aprovel 300mg+25mg Tablet 14 ‘S

  • Mild to moderate hepatic (liver) impairment
  • Biliary obstruction (blockage of bile ducts)
  • Salt or volume depletion
  • Aortic or mitral stenosis (heart valve narrowing)
  • Malignant hyperthermia (severe reaction to certain drugs used for anesthesia)
  • Hypertensive crisis (severe increase in blood pressure)
  • Moderate to severe renal (kidney) impairment 
  • Renal artery stenosis (narrowing of blood vessels in kidney)
  • Heart failure or post MI (heart attack)
  • Old age
  • Diabetes

Please monitor serum potassium in the elderly and in renal impairment (kidney damage) before taking the Co-Aprovel 300mg+25mg Tablet 14 ‘S.

Interactions With Other Medications

Please tell your doctor about the use of the following before using Co-Aprovel 300mg+25mg Tablet 14 ‘S:

  • K+ supplements
  • NSAIDs (Aspirin, Ibuprofen,Naproxen)
  • Lithium  (Prescribed for bipolar and/or depression)
  • Other hypertensive medicines
  • Skeletal muscle relaxants (such as barbiturates)
  • Diabetic drugs (such as insulin,glipizide)
  • Cyclosporine (immunosuppressant drug)
  • Cholestyramine (cholesterol controlling medicine)

Adverse Effects

Common Adverse Effects

Like most medicines,Co-Aprovel 300mg+25mg Tablet 14 ‘S has certain side effects which include:

  • Lightheadedness
  • Dizziness
  • Dehydration (leads to extreme thirst and dry mouth)
  • Muscle Cramps
  • Headaches
  • Stomach problems (diarrhea,nausea,vomiting)

These effects tend to be mild and resolve in a few days of taking Co-Aprovel 300mg+25mg Tablet 14 ‘S.

Rare Adverse Effects

If any of the following adverse effects are seen or felt,the patient is advised to immediately contact their doctor.

  • Extreme fatigue
  • Feeling faint
  • Change in amount of urine
  • Shortness of breath 
  • Allergic symptoms (Such as rash,swelling on lips or face)
  • Difficulty with vision (eye pain)
  • Joint pain
  • Swelling of hands and/or feet

How To Cope With Some Of The Adverse Effects

  • Feeling dizzy (lightheaded) or weak -If the medication makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Feeling or being sick (nausea or vomiting) or diarrhoea -Avoid eating rich or spicy food. It might help to take medication after food. If you’re sick, try drinking small, frequent sips of water. If you have diarrhoea, replenish with plenty of water or other fluids. 
  • Headache– In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe.
  • Dehydration- Patients are recommended to always care around a water bottle with them wherever they go and periodically keep sipping to prevent thirst and extremely dry mouth.Ice pops in hot weather and energy drinks (verified by the doctor) are helpful in combating dehydration

 Key Facts About Co-Aprovel 300mg+25mg Tablet 14 ‘S

  • Co-Aprovel 300mg+25mg Tablet 14 ‘S is prescribed when treatment with either angiotensin II blockers alone or with a diuretic alone isn’t effective in treating high blood pressure.
  • Co-Aprovel 300mg+25mg Tablet 14 ‘S is not safe to be given to pregnant or lactating mothers.
  • Co-Aprovel 300mg+25mg Tablet 14 ‘S may cause increased amounts of urine.
  • One tablet of Co-Aprovel 300mg+25mg Tablet 14 ‘S per day is prescribed. 
  • Co-Aprovel 300mg+25mg Tablet 14 ‘S is not to be taken without a doctor’s prescription.

FAQS

#1.CAN I CONSUME ALCOHOL WITH Co-Aprovel 300mg+25mg Tablet 14 ‘S?

Alcohol is also known to lower your blood pressure which if taken with the medication may lead to extreme dizziness. It is best to avoid the intake of alcohol during the course of your treatment.

#2.CAN LIFESTYLE CHANGES HELP ME WITH MY CONDITION?

Yes. you can adopt certain healthy lifestyle changes in order to help with high blood pressure. These include quitting smoking, avoiding alcohol, eating a wholesome diet consisting of fresh vegetables and fruits with the cut down of salt, and incorporating physical activity in your daily routine.

#3.CAN I TAKE Co-Aprovel 300mg+25mg Tablet 14 ‘S DURING MY PREGNANCY?

No. This medication has been known to cause harm to the fetus and cause complications during your pregnancy.Hence, it is advised to consult your doctor if you are pregnant or planning to become pregnant or may think you are pregnant.

#4.WHAT IF I TAKE TOO MUCH OF Co-Aprovel 300mg+25mg Tablet 14 ‘S?

In case of too much consumption by accident, kindly contact your doctor or nearby hospital straight away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

#5.WHAT IF I FORGET TO TAKE THE Co-Aprovel 300mg+25mg Tablet 14 ‘S?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next day, do not double the dose and take your medication as per schedule as that will lead to serious adverse effects. If this happens very often, try setting an alarm as a reminder.

#6.CAN I TAKE Co-Aprovel 300mg+25mg Tablet 14 ‘S DURING MY PREGNANCY?

No. This medication has been known to cause harm to the fetus and cause complications during your pregnancy.Hence, it is advised to consult your doctor if you are pregnant or planning to become pregnant or may think you are pregnant.

#7.WHAT IF I TAKE TOO MUCH OF Co-Aprovel 300mg+25mg Tablet 14 ‘S?

In case of too much consumption by accident, kindly contact your doctor or nearby hospital straight away. The amount of medication that can result in severe side effects varies from person to person. An overdose results in slowing down of heart rate and difficulty breathing accompanied by dizziness and fainting spells.

#8.WHAT IF I FORGET TO TAKE THE Co-Aprovel 300mg+25mg Tablet 14 ‘S?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next day, do not double the dose and take your medication as per schedule as that will lead to serious adverse effects. If this happens very often, try setting an alarm as a reminder.

#9.IS IT SAFE TO HAVE Co-Aprovel 300mg+25mg Tablet 14 ‘S BEFORE UNDERGOING ANY SURGICAL PROCEDURE?

If the surgical procedure involves general anesthesia, the surgeon may ask the patient to stop their intake of the drug for 24 hours as general anesthesia also tends to lower blood pressure levels in a few patients.

#10.HOW IS Co-Aprovel 300mg+25mg Tablet 14 ‘S SUPPOSED TO BE TAKEN?

The medicine can be ingested orally (from the mouth) either with or without food and is to be taken with water to ease the medicine into the throat.

#11.HOW DOES Co-Aprovel 300mg+25mg Tablet 14 ‘S WORK?

Co-Aprovel 300mg+25mg Tablet 14 ‘S works by preventing both the unnecessary retention of fluid in the body and the narrowing of blood vessels and therefore, allowing normal amounts of blood flow and easy access of blood to the various organs and easing the flow of blood within the vessel itself.

 Co-Aprovel 300mg+25mg Tablet 14 ‘S is able to bring about the desired effect by the perfect and unique combination of two chemical groups known as Angiotensin II Receptor Blockers (prevent decrease in blood vessel diameter by blocking angiotensin,a natural hormone found in the human body that works by narrowing blood vessels) and Diuretics (prevent fluid retention in the body by allowing excessive  fluid to be lost via urine).

#12.HOW TO STORE Co-Aprovel 300mg+25mg Tablet 14 ‘S?

Co-Aprovel 300mg+25mg Tablet 14 ‘S is to be kept away from the reach of children,in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.

#13.WHY MUST I PROTECT MY SKIN FROM THE SUN WHILE TAKING Co-Aprovel 300mg+25mg Tablet 14 ‘S?

Co-Aprovel 300mg+25mg Tablet 14 ‘S can make the skin susceptible to certain non-melanoma cancers of the lip and skin.Patients are advised to wear sunscreen along with hats and gloves whenever possible to protect themselves from sun damage.

#14.CAN Co-Aprovel 300mg+25mg Tablet 14 ‘S CAUSE DIZZINESS? IF SO, HOW SHOULD I MANAGE IT?

Yes. It can cause dizziness as one of the most common side effects. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during the course of your treatment, as it may worsen the dizziness.

#15.WHAT COMMON ADVERSE EFFECTS WILL I HAVE WITH Co-Aprovel 300mg+25mg Tablet 14 ‘S?

Some common adverse effects are as follows,

  • Lightheadedness
  • Dizziness
  • Dehydration (leads to extreme thirst and dry mouth)
  • Muscle Cramps
  • Headaches
  • Stomach problems (diarrhea,nausea,vomiting)

These effects are mild and tend to resolve on their own in a few days time;if the patient is unable to deal with the adverse effects they ought to call their doctor,it is likely that they might change the dosage of the drug or change the drug altogether. 

#16.IS IT NORMAL TO HAVE INCREASED FREQUENCY OF URINATION WITH Co-Aprovel 300mg+25mg Tablet 14 ‘S?

Yes.It is completely normal as this drug includes a diuretic which works by decreasing unnecessary fluid retention in the body and thus,lowering raised levels of blood pressure back to normal.

#17.WHAT LAB TESTS WILL BE PRESCRIBED WHILE TREATMENT WITH Co-Aprovel 300mg+25mg Tablet 14 ‘S AND HOW OFTEN?

Kidney and liver function tests along with blood tests to keep a check on serum potassium levels are advised to be done periodically.It is also advised that patients learn to monitor their own blood pressure levels daily from the comfort of their homes and inform their doctor of any changes seen.

#18.IS IT SAFE TO TAKE CHOLESTEROL MEDICINES ALONG WITH Co-Aprovel 300mg+25mg Tablet 14 ‘S?

Ingesting cholesterol lowering medication along with Co-Aprovel 300mg+25mg Tablet 14 ‘S decreases its effectiveness and therefore,it is advised that patients use their cholesterol medicine 4-6 hours before having ‘product’

#19.CAN I DRIVE AFTER TAKING THIS MEDICATION?

This medication is known to make you dizzy hence, if that happens kindly avoid driving or operating any heavy machinery.

Additional information

Type

Tablet

Feature

300mg+25mg

Unit

'S

Formula

Irbesartan

Composition

Hydrochlorothiazide 25 mg + Irbesartan 300 mg

Brand

Sanofi-aventis

Prescription Required

Yes