Zampicillin Dry 125mg Suspension 60 ml

Description

About

Zampicillin Dry 125mg Suspension 60 ml belongs to a class of drugs called “beta-lactam antibacterials/penicillins” whose working action is categorized as broad-spectrum. Zampicillin Dry 125mg Suspension 60 ml is used to treat various bacterial infections, such as chest infections (including pneumonia), urinary tract infections, dental abscesses, ear infections, wound infections, septicemia, bone infections, meningitis. Zampicillin Dry 125mg Suspension 60 ml is an antibiotic from the penicillin group of medicines that works by preventing the formation of a key component of the bacterial cell wall, essential for the survival of the bacteria. 

Zampicillin Dry 125mg Suspension 60 ml is chemically composed of ampicillin. It is effective against a variety of gram-positive and gram-negative infections. Zampicillin Dry 125mg Suspension 60 ml works by targeting bacterial cell walls, leading to bacterial cell death. Dosage of Zampicillin Dry 125mg Suspension 60 ml depends on age, body weight, the severity of the condition, patient’s response to the medicine, and their comorbidities. 

It is available on prescription in oral suspension to be used as per prescription and is more suited to children younger than 12 years of age with dosage-dependent upon body weight and severity of infection. Zampicillin Dry 125mg Suspension 60 ml is the best-prescribed for the treatment of bacterial infections in patients who are not allergic to Zampicillin Dry 125mg Suspension 60 ml or penicillin groups of drugs. Common side effects of this medication are nausea, vomiting, diarrhea, fatigue, oral ulcers, thrush, etc.

Indications

It is used in the treatment of:

• Infections of the respiratory tract (nose, throat, larynx, trachea, bronchi, and lungs)
• ENT (eyes, nose, and throat) infections
• Urinary tract infections
• Skin and soft tissue infections.
• Dental infections (dental abscesses – buildup of pus inside teeth and gums)
• Meningitis 
• Prophylaxis of bacterial endocarditis (bacterial infection of the inner layer of the heart or heart valves)
• Septicemia 
• Pelvic infections
• Post-surgical infections
• Wound infections 

How does Zampicillin Dry 125mg Suspension 60 ml work

Zampicillin Dry 125mg Suspension 60 ml chemically is composed of Ampicillin which belongs to the penicillin group of medicines that works by preventing the formation of a key constituent of the protective bacterial cell wall, peptidoglycan through Penicillin-binding proteins associated with its formation. The cell wall is essential for the survival and growth of the bacteria thereby, preventing its spread.

How To Use Zampicillin Dry 125mg Suspension 60 ml

Zampicillin Dry 125mg Suspension 60 ml is to be ingested orally (by mouth) thrice, daily, or as directed by the doctor. It can be ingested preferably without food, for better absorption of the medicine take it at least 1 hour before your meal. The patient is advised to take each dose at the same time each day keeping a 6-hour gap in between each dose. Zampicillin Dry 125mg Suspension 60 ml is available as an oral suspension for use in pediatric patients. Make sure to follow the doctor’s advice carefully regarding dosage and proper use. Dry powder is packaged in a glass bottle to be re-assembled as a suspension by adding the prescribed amount of water, given on the label, read it carefully. Make sure to shake the bottle well before each use. A calibrated spoon/device is provided or can be bought from a pharmacy for dosing purposes. Do not use household spoons/devices for dosing out Zampicillin Dry 125mg Suspension 60 ml.

If you miss a dose of the medication, make sure you take it as soon as possible on that same day except if less than 4 hours are remaining till the next dose. If you don’t remember taking your dose on schedule until the next dose time or the next day, do not double the dose and take your medication as per prescribed timings. Zampicillin Dry 125mg Suspension 60 ml is to be ingested for a specific number of days determined by the physician depending on the patient’s illness and their response to treatment. It is imperative not to stop Zampicillin Dry 125mg Suspension 60 ml earlier than the specified time as that may lead to a return of the infection or ineffective therapy in the future due to bacterial resistance. Dry suspension when not constituted can be kept at room temperature in a cool environment but after assembly into suspension, it must be stored in a refrigerator at 2 to 8 *C and must be used within a month

Dosage 

Dosage is completely dependent on the weight, age, severity of infection, patient’s response to the medicine, and their comorbidities. Your doctor may vary your dosage accordingly.

Dosage forms and potencies:

Zampicillin Dry 125mg Suspension 60 ml is available as a dry powder in the following potency:

• 125 mg/5 ml   

Adult Dosage

Capsules and IV injections work more efficiently in adults

Pediatric Dosage

Zampicillin Dry 125mg Suspension 60 ml is prescribed after carefully calculating per patient’s weight and severity of ongoing infection. Zampicillin Dry 125mg Suspension 60 ml can be given to children under 12 years:

Neonates < 3 months 

Dosing should be carefully calculated due to less developed kidneys. Follow doctors’ prescriptions tailored for your child. The maximum dose must not exceed 30 mg/kg in divided doses, 12 hours apart

3 months and older

Mild to Moderate infections: 20 to 25 mg/kg, 8 to 12 hours apart

Severe infections: 40 to 50 mg/kg, 8 to 12 hours apart

The maximum dose must not exceed 100 mg/kg in divided doses, per day

Children over 40 kg: should be prescribed capsules/ tablets – 500 mg orally, thrice a day every 6 to 8 hours

Elderly Dosage

Capsules and IV injections work more efficiently in adults. Doses must be adjusted keeping in mind comorbidities. 

* NOTE: Doses may vary and can be adjusted if considered appropriate for the given patient or infection. Given above are doses according to the guidelines generally prescribed to treat infections. Always follow the doses advised by your doctor according to your condition

Pregnancy use and lactation

 Zampicillin Dry 125mg Suspension 60 ml is classified as a pregnancy category B drug by FDA (meaning no evidence of any risk to the human fetus in controlled animal trials but insufficient data on humans is available). If you are pregnant, think you may be pregnant, or are planning on conceiving a baby, please consult your doctor before using Zampicillin Dry 125mg Suspension 60 ml regarding its safe use. Zampicillin Dry 125mg Suspension 60 ml is also secreted in human milk, if you are breastfeeding, please consult your doctor before taking Zampicillin Dry 125mg Suspension 60 ml. 

Contraindications

Please tell your doctor if you have a history of any of the following before using Zampicillin Dry 125mg Suspension 60 ml:

• Allergy to Zampicillin Dry 125mg Suspension 60 ml or other penicillins
• Kidney impairment
• Severe liver disease
• History of Zampicillin Dry 125mg Suspension 60 ml associated or penicillin associated jaundice or hepatic (liver) dysfunction.
• Infectious mononucleosis (glandular fever caused by EBV virus).
• If you have recently had, or are about to have, any vaccinations as it may decrease the effectiveness of the vaccine.
• Hereditary phenylketonuria (The liquid form is not suitable as it may contain aspartame which may be harmful to you)
• Immunizations /live bacterial vaccines such as Typhoid vaccine
• Patients with drug resistance to Penicillins

Precautions

Please tell your doctor about any of the following conditions before using Zampicillin Dry 125mg Suspension 60 ml:

• History of allergy to antibiotics and drugs
• Mild to moderate liver impairment
• Mild to moderate kidney impairment
• Conditions such as mononucleosis caused by EBV or leukemia, affecting the lymphoid gland, there is a risk of having toxic reactions in such patients. Report to your doctor if you notice a rash on the skin, pruritus, or any unusual symptom
• Long-term use of Zampicillin Dry 125mg Suspension 60 ml can put you at risk of developing inflammation of the intestine (Pseudomembranous colitis). If you experience unusual diarrhea or prolonged diarrhea with Zampicillin Dry 125mg Suspension 60 ml, report to your doctor immediately
• There can be a superimposed infection with opportunistic microbes, consult your doctor if you notice an increased or an unusual infection in your body 
• Neonates must be monitored carefully for jaundiced appearance other than physiological jaundice. Zampicillin Dry 125mg Suspension 60 ml has the potential to raise blood bilirubin levels
• It is a good approach to regularly monitor kidney, liver, and blood cell function and bilirubin if you are on a long-term prescription with Zampicillin Dry 125mg Suspension 60 ml
• In case of moderate to severe infections, avoid getting vaccine shots till you have completed the antibiotic cover to avoid unpleasant results
• Clostridium Difficile associated diarrhea can occur with the use of certain antibiotics. Immediately contact tor doctor
• While having lab work done on blood, always tell the laboratory personnel about current drugs that you are taking since it can affect the results, like glucose tests, LFTs, clotting time, etc
• There is a likelihood of developing antibiotic resistance with improper use, make sure you complete the entire course even if you feel better 

Interaction with other medications

Certain medications could interact with Zampicillin Dry 125mg Suspension 60 ml, hence, in that case, your doctor might alter your dosage, so please inform your doctor about the use of the following before taking Zampicillin Dry 125mg Suspension 60 ml:

• Anticoagulants such as warfarin
• Sulphonamides 
• Acetylsalicylic acid
• Allopurinol and probenecid (used to treat gout)
• Tetracyclines, doxycycline
• Methotrexate (used to treat cancer or rheumatic diseases)
• Other antibiotics
• Vaccines (BCG, Typhoid, cholera)
• Thiazide diuretics 
• Erythromycin 

Adverse effects

Like most medicines, Zampicillin Dry 125mg Suspension 60 ml has some side effects which include:

Common Side Effects

• Nausea 
• Diarrhea 
• Abdominal pain
• Skin rash
• Pruritus

Serious Side Effects

• Hypersensitivity/allergic skin reactions
• Hepatitis (inflamed or infected liver)
• Hematological (blood-related) – affects blood cells
• CNS effects
• Pseudomembranous colitis (inflamed large intestine)
• Oral ulcers 
• Agranulocytosis/ hemolytic anemia
• Increased INR 
• Bruising or skin discoloration
• Crystal formation in the skin 
• Glossitis 
• Thrombocytopenia purpura 

How to cope with some of the adverse effects

• Nausea (feeling sick) – Take Zampicillin Dry 125mg Suspension 60 ml with meals to avoid feeling sick.
• Vomiting/Diarrhea – Keep yourself hydrated by having lots of fluids and if the problem persists, consult your doctor before taking any medication for vomiting and diarrhea
• Skin Rash – This can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. Antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
• Oral Thrush – Thia can develop in cases of prolonged antibiotic therapy, consult your doctor if this happens. Usually, patients are advised to swish and spit through their oral cavities with dispersible antifungal tablets or drops/ mouthwash as prescribed by a doctor, at least twice daily after ingesting Zampicillin Dry 125mg Suspension 60 ml
• Flatulence – Can be eased by consuming smaller, more frequent meals that don’t trigger your flatulence. Getting a minimum of 30 minutes of daily exercise has shown great results in combating flatulence. 
• Heartburn – can be dealt with by chewing on mint-flavored gum that’ll help neutralize the acid in the body. Standing up straighter, adding ginger to the daily diet, elevating the patient’s upper body, and having licorice supplements has shown to provide relief.

FAQ’s

#1. What Exactly Does Zampicillin Dry 125mg Suspension 60 ml Do?

Zampicillin Dry 125mg Suspension 60 ml is an antibiotic from the penicillin group of medicines that works by preventing the formation of the protective bacterial wall, essential for the survival of the bacteria, 

#2. How Long Does It Take For Zampicillin Dry 125mg Suspension 60 ml To Start Working?

Antibiotics start working almost immediately. It takes around an hour for Zampicillin Dry 125mg Suspension 60 ml to start working in your body. However, you will feel symptom relief and show improvement within 1-3 days of taking Zampicillin Dry 125mg Suspension 60 ml.

#3. For How Long Will I Have To Take Zampicillin Dry 125mg Suspension 60 ml?

The duration for using Zampicillin Dry 125mg Suspension 60 ml depends on the type and severity of the infection. You will probably be prescribed to take it for 5-14 days. If you do not feel better after completing your course of medicine, or if you feel worse at any time, contact your doctor.

#4. Can I Stop Taking Zampicillin Dry 125mg Suspension 60 ml?

Do not just stop taking the medicine, make sure to complete your treatment course even if you feel better. Stopping it suddenly may cause the bacteria to start multiplying again and the infection could come back. The bacteria could also develop resistance to the antibiotic which will make it ineffective in the future.

#5. Can I Drink Alcohol With Zampicillin Dry 125mg Suspension 60 ml?

Consuming alcohol when taking Zampicillin Dry 125mg Suspension 60 ml is not known to cause any problems. However, it is a good practice to avoid consuming it simultaneously 

#6. What If I Take Too Much Of Zampicillin Dry 125mg Suspension 60 ml?

If you have taken one extra dose of Zampicillin Dry 125mg Suspension 60 ml it is unlikely to harm you. Side effects of taking Zampicillin Dry 125mg Suspension 60 ml more than the prescribed dose are upset stomach, nausea, vomiting and diarrhea, severe abdominal pain, or increased sweating. Contact your doctor immediately if you have taken 2 or more doses and experience serious symptoms. 

#7. What If I Forget To Take Zampicillin Dry 125mg Suspension 60 ml?

In case you miss a dose, take it as soon as you remember unless the time remaining till the next dose is less than 4 hours in which case do not try to make up for the missed dose by doubling it up. If it helps to remind you, set an alarm, mobile phone application, or a pill organizer, so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

#8. Can I Take Zampicillin Dry 125mg Suspension 60 ml During Pregnancy Or Breastfeeding?

It is generally considered safe but if you are pregnant, or are planning to conceive a baby, please consult your doctor before using Zampicillin Dry 125mg Suspension 60 ml. If you are breastfeeding, please consult your doctor before taking Zampicillin Dry 125mg Suspension 60 ml.

#9. Is It Safe To Use Zampicillin Dry 125mg Suspension 60 ml For A Long Term?

Zampicillin Dry 125mg Suspension 60 ml is usually generally recommended for 5-14 days, therefore, do not take it for any longer than the prescribed period. 

#10. What If Zampicillin Dry 125mg Suspension 60 ml Gives Me Thrush?

At times people develop a fungal infection called thrush after taking a course of antibiotics like Zampicillin Dry 125mg Suspension 60 ml. This is because antibiotics kill the normal harmless bacteria that help to protect you against such infections to allow opportunistic microbes to show overgrowth. Antifungal rinses prescribed by the doctor will help treat this

#11. Can I Drive Or Ride A Bike After Taking Zampicillin Dry 125mg Suspension 60 ml?

Zampicillin Dry 125mg Suspension 60 ml shouldn’t affect your being able to drive or ride a bike. If you experience dizziness kindly avoid such activities

#12. How Should Zampicillin Dry 125mg Suspension 60 ml Be Stored?

Keep the medicine tightly closed in the packet it came in. Dry suspension when not constituted can be kept at room temperature, away from excess heat and moisture.  But after assembly into suspension, it must be stored in a refrigerator at 2 to 8 *C and must be used within a month